CAS 958852-01-2: GSK1059615
Formula:C18H11N3O2S
Synonyms:- Gsk 1059615
- 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione
- (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
- (Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione
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GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Formula:C18H11N3O2SPurity:≥95% - ≥95%Color and Shape:SolidMolecular weight:333.36(Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione
CAS:(Z)-5-((4-(Pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione is a potent inhibitor of the epidermal growth factor receptor (EGFR). It has been shown to inhibit the growth of solid tumours in animals and human cells. The drug has also been found to be effective against pancreatitis in mice. This agent binds to EGFR and inhibits the function of this receptor, which is involved in many cellular processes such as cell proliferation, differentiation, and apoptosis. It has been shown that (Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4 dione can bind to other proteins that are structurally related to EGFR with high affinity. These proteins include receptors for erythropoietin, prolactin, luteinizing hormone,Purity:Min. 95%
