CAS 959763-06-5: CH5138303

CH5138303 is a compound that binds to the influenza virus and inhibits its replication. CH5138303 inhibits the activity of both transcription-polymerase chain reaction and ribonucleotide reductase, which are enzymes essential for viral RNA synthesis. This compound also binds to the influenza virus receptor, inhibiting binding and subsequent entry into the cell. In addition, CH5138303 has been shown to have anti-inflammatory effects in animal models of bowel disease and inflammatory bowel disease. The hydroxyl group on this molecule may be important for these biological properties because it can form hydrogen bonds with other molecules or ions.

CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.