CAS 960-16-7: Phenyltri-n-butyltin

Stability Moisture Sensitive Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

It is applied in chemical research. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Tributylphenyltin is a protein inhibitor that binds to specific amino acid residues in the active site of enzymes, inhibiting their activity. This compound is used in the treatment of inflammatory diseases and is a potential substitute for the use of sodium salts or nitrogen nucleophiles as protein inhibitors. Tributylphenyltin has been shown to be nanosized, which results in increased efficiency. It also binds at a factor receptor site and inhibits growth factor activity. This agent can be synthesized using cross-coupling reactions between an aromatic hydrocarbon and a halide that are efficient and yield high-quality products.