1-(1H-indol-2-yl)-N-methylethanamine, also known as 5-Methyltryptamine, is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This compound features a methyl group attached to the nitrogen atom of the ethylamine side chain, contributing to its unique properties. It is classified as a tryptamine derivative, which is significant in various biological processes, including neurotransmission. The presence of the indole moiety suggests potential interactions with serotonin receptors, making it of interest in pharmacological research. The compound is typically a colorless to pale yellow liquid or solid, depending on its purity and form. Its solubility in polar solvents indicates its potential for biological activity. As with many tryptamines, it may exhibit psychoactive properties, although specific effects can vary based on dosage and individual response. Safety and handling precautions are essential due to its potential biological activity and the need for further research to fully understand its effects and applications.

1-(1H-indol-2-yl)-N-methylethanamine

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2-[1-(Methylamino)ethyl]indole

Applications Used in synthesis of 3-amino-5H-pyrido[4,3-b]indoles, carcinogenic .gamma.-carbolines.
References Akimoto, H., et al.: Bull. Chem. Soc. Jpn., 58, 123 (1985),


CAS 96286-08-7: 1-(1H-indol-2-yl)-N-methylethanamine

2-[1-(Methylamino)ethyl]indole

Ref: 3D-FM25773

2-[1-(Methylamino)ethyl]indole

Ref: TR-M286150

2-[1-(Methylamino)ethyl] Indole

Ref: 4Z-I-091064