Calcitonin gene-related peptide (CGRP) in rats, identified by the CAS number 96827-03-1, is a neuropeptide that plays a significant role in various physiological processes, particularly in the nervous system and cardiovascular regulation. CGRP is derived from the calcitonin gene and is known for its potent vasodilatory effects, contributing to the regulation of blood flow and blood pressure. It is primarily expressed in sensory neurons and is involved in pain transmission and the modulation of inflammatory responses. The peptide exists in two forms, alpha and beta, with the alpha form being more prevalent in the central nervous system. CGRP is also implicated in migraine pathophysiology, making it a target for therapeutic interventions in migraine treatment. Its biological activity is mediated through specific receptors, which are part of the class B G-protein-coupled receptor family. Overall, CGRP is a crucial molecule in neurobiology and has significant implications for understanding and treating various neurological and cardiovascular conditions.

calcitonin gene related peptide rat

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CAS 96827-03-1: calcitonin gene related peptide rat

Calcitonin Gene Related Peptide, Rat

Ref: 02-J66827