CAS: 97024-74-3

Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that is used to relieve the symptoms of osteoarthritis and rheumatoid arthritis. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), which are enzymes that produce prostaglandins in the body. Rofecoxib has been shown to inhibit COX-1 in the cardiovascular system, which may be responsible for its cardioprotective effects. This drug also has the ability to stabilize platelets and prevent blood from clotting, which may be due to its inhibition of COX-2.