N-ω-tosyl-D-arginine is a synthetic amino acid derivative characterized by the presence of a tosyl group, which enhances its reactivity and solubility in organic solvents. This compound is primarily utilized in biochemical research and peptide synthesis due to its ability to act as a substrate or inhibitor for various enzymes, particularly proteases. The presence of the D-arginine configuration allows for specific interactions in biological systems, making it valuable in studying protein structure and function. N-ω-tosyl-D-arginine is typically a white to off-white solid, and it is soluble in polar organic solvents. Its molecular structure includes an amino group, a carboxylic acid group, and a tosyl group, contributing to its unique chemical properties. Safety data indicates that, like many chemical reagents, it should be handled with care, using appropriate personal protective equipment to avoid potential health hazards. Overall, N-ω-tosyl-D-arginine serves as an important tool in the field of biochemistry and molecular biology.

N-ω-tosyl-D-arginine

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Nw-(4-Toluenesulfonyl)-D-arginine

H-D-Arg(Tos)-OH is a synthetic amino acid that has been shown to lower blood pressure. It is an agonist at the alpha2A receptor, which is a pharmacophore that stimulates the release of norepinephrine and epinephrine. H-D-Arg(Tos)-OH also acts as an antagonist at the alpha2B receptor, which is also a pharmacophores for blood pressure regulation. H-D-Arg(Tos)-OH mimics nicotine by binding to nicotinic acetylcholine receptors in the brain. This drug has been shown to reduce symptoms of hypertension, such as headaches, dizziness, and chronic fatigue. The structure of H-D-Arg(Tos)-OH can be modified by changing the c1-c10 alkyl group on its side chain to form analogs with different properties. A data base containing information about these analogs can be found here: https://www.ncbi

CAS 97233-92-6: N-ω-tosyl-D-arginine

Nw-(4-Toluenesulfonyl)-D-arginine

Ref: 10-F492901

H-D-Arg(Tos)-OH

Ref: 3D-FA43054