CAS: 97399-71-8

3α-Hydroxytanshinone IIA (Compound 5), an isolatable compound from the roots of Salvia miltiorrhiza [1], exhibits specific characteristics.

3Alpha-Hydroxytanshinone IIA is a bioactive compound derived from Salvia miltiorrhiza, a plant commonly known as Danshen. This compound is characterized as a diterpenoid, which boasts a diverse range of biological activities. As an active constituent of this traditional medicinal herb, 3Alpha-Hydroxytanshinone IIA exerts its effects primarily through the modulation of oxidative stress pathways and various signaling cascades involved in inflammation and apoptosis. Its mode of action includes the inhibition of key enzymes and pathways such as the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK), which are crucial in inflammatory responses and cellular stress management. These properties make it a molecule of significant interest in scientific research, particularly for its potential therapeutic applications. The compound has been investigated for its uses in treating conditions related to oxidative stress and inflammation, such as cardiovascular diseases, cancer, and neurodegenerative disorders. Its ability to modulate complex cellular processes underpins its potential as a therapeutic agent, warranting further exploration in preclinical and clinical studies.