CAS: 97743-99-2

rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.

1-(4-Fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile hydrochloride is a fluorescent probe that has been extensively studied as a potential diagnostic agent. It has been shown to be a potent inhibitor of human serum and porcine alkaline phosphatase. The optimum flow rate for the assay is 0.2 mL/min. A quinidine binding assay is used to measure the inhibitory potency of 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile hydrochloride. This method can be carried out using a UV spectrophotometer or an HPLC system with fluorescence detection. The reagent should be deionized water and acetonitrile in equal parts for the chrom

Stability Hygroscopic Applications A metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Gnerre, C., et al.: J. Pharm. Pharmacol., 53, 1125 (2001), Hagg, S., et al.: Br. J. Clin. Pharmacol., 51, 169 ( 2001), von Moltke, L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Reis, M., et al.: Ther. Drug Monit., 27, 469 (2005),

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

rac Desmethyl Citalopram Hydrochloride