Boc-Arg(Boc)2-OH, also known as Nα,Nα-bis(Boc)-L-arginine, is a protected form of the amino acid arginine, commonly used in peptide synthesis and biochemistry. The "Boc" (tert-butyloxycarbonyl) groups serve as protecting groups for the amino functionalities, allowing for selective reactions without interference from the amino groups. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its structure includes a guanidinium group characteristic of arginine, which contributes to its basicity and potential interactions in biological systems. The presence of multiple Boc groups enhances stability and facilitates the handling of the compound during synthesis. Boc-Arg(Boc)2-OH is often utilized in the preparation of peptides where the arginine residue needs to be protected until the desired stage of synthesis, making it a valuable intermediate in the field of medicinal chemistry and peptide research.

Boc-Arg(Boc)2-OH

Boc-Arg(Boc)₂-OH

(S)-5-(1,3-Bis(tert-butoxycarbonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoic acid

11-Oxa-2,4,9-triazatridecanoic acid,8-carboxy-4-[(1,1-dimethylethoxy)carbonyl]-3-imino-12,12-dimethyl-10-oxo-, 1-(1,1-dimethylethyl) ester, (8S)-

Boc-Arg(Boc)2-OH is a protected derivative of the amino acid arginine. The Boc (tert-butyloxycarbonyl) groups shield both the amino group and the side chain's guanidine functionality. This protection scheme allows for its selective incorporation during peptide synthesis while offering stability under various reaction conditions. Boc-Arg(Boc)2-OH has been also used in the synthesis of amino acid prodrugs of cytotoxic anthraquinones, demonstrating its potential utility in developing targeted cancer therapies.

CAS 97745-69-2: Boc-Arg(Boc)2-OH

Boc-Arg(Boc)₂-OH

Ref: 01-4011878

(S)-5-(1,3-Bis(tert-butoxycarbonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoic acid

Ref: 10-F544619

11-Oxa-2,4,9-triazatridecanoic acid,8-carboxy-4-[(1,1-dimethylethoxy)carbonyl]-3-imino-12,12-dimethyl-10-oxo-, 1-(1,1-dimethylethyl) ester, (8S)-

Ref: IN-DA00IJZ5

Boc-Arg(Boc)2-OH

Ref: 3D-FB111237