CAS: 97845-72-2

Penciclovir diacetate is an antiviral compound, which is synthesized as a prodrug derivative of penciclovir. This compound originates from chemical modification processes designed to improve the pharmacokinetic properties of its active metabolite. Once administered, penciclovir diacetate undergoes in vivo conversion to penciclovir, an active nucleoside analog. The mode of action involves selective inhibition of viral DNA polymerase after being phosphorylated to its triphosphate form, thereby impeding viral DNA synthesis and replication. Penciclovir diacetate is extensively used in research focused on the herpes virus, particularly herpes simplex virus (HSV). It offers valuable insights into the development of therapeutic strategies aimed at mitigating viral infections. In experimental settings, penciclovir diacetate serves as an essential tool for evaluating antiviral efficacy and understanding viral resistance mechanisms.