
CAS 98015-53-3: Carbonochloridic acid, 1,2,2,2-tetrachloroethyl ester
Formula:C3HCl5O2
InChI:InChI=1S/C3HCl5O2/c4-1(3(6,7)8)10-2(5)9/h1H
InChI key:InChIKey=RINXZIYBNVEZRT-UHFFFAOYSA-N
SMILES:C(OC(Cl)=O)(C(Cl)(Cl)Cl)Cl
Synonyms:- (1R)-1,2,2,2-Tetrachloroethyl chloroformate
- 1,2,2,2,Tetrachloroethyl chloroformate
- 1,2,2,2-Tetrachloroethyl carbonochloridate
- Carbonochloridic acid, 1,2,2,2-tetrachloroethyl ester
- Formic acid, chloro-, 1,2,2,2-tetrachloroethyl ester
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Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester
CAS:Controlled ProductApplications Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester is used in the synthesis of Doxorubicin (D558000), is used as an antineoplastic. Also used in the synthesis of metabolites of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. References Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969), Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)Formula:C3HCl5O2Color and Shape:NeatMolecular weight:246.304