CAS 99-05-8: 3-Aminobenzoic acid

3-Aminobenzoic acid is a cyclic peptide that has been shown to inhibit nitrite ion formation in the human body. Nitrite ions are produced from nitric oxide and bind to hemoglobin, forming methemoglobin. 3-Aminobenzoic acid does not have a direct effect on nitric oxide, but it inhibits the conversion of nitrite ions to nitrate ions by reacting with the hemoglobin in blood. This prevents methemoglobin from being formed and reduces the risk of oxygen deprivation. 3-Aminobenzoic acid is synthesized by humans in response to an infection or other injury and can be found in human serum. The crystal structures of 3-aminobenzoic acid were determined by x-ray crystallography methods, which showed that this molecule forms hydrogen bonds with water molecules. These interactions stabilize its structure and allow for intramolecular hydrogen bonding interactions between its amino acids. The reaction mechanism was determined by kinetic energy

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

It finds its application as crystalline Intermediate for azo dyes, pharmaceuticals, and X-ray contrast media. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

3-Aminobenzoic acid

Impurity Mesalazine EP Impurity D Applications 3-Aminobenzoic Acid, is a chemoattractants against Pseudomonas strains. A reactant used in the preparation of influenza neuraminidase inhibitors, inhibitors of transthyretin amyloid fibril formation and inhibitors of the protein chaperone Hsp90. References Menzella, H. et al.: J. Med. Chem., 52, 1518 (2009); Johnson, S. et al.: J. Med. Chem., 48, 1576 (2005); Parales, R.: App. Environ. Microbiol., 70, 285 (2004);