CAS 99-40-1: 2-Chloro-3′,4′-dihydroxyacetophenone

Noradrenaline impurity E CRS

Applications 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone (cas# 99-40-1) is a compound useful in organic synthesis.

Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoi

3,4-Dihydroxyphenacyl chloride

2-Chloro-3',4'-dihydroxyacetophenone is used as a styptic adrenobazone, quasi adrenaline drug gasp spirit of intermediates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Chloro-3',4'-dihydroxyacetophenone is a potent inhibitor of two enzymes that are involved in the synthesis of fatty acids: 3-ketoacyl-coenzyme A synthase and 3-hydroxyacyl-coenzyme A dehydrogenase. This inhibition leads to the accumulation of acetate and reduced levels of fatty acids, which are important for cell growth. 2-Chloro-3',4'-dihydroxyacetophenone has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, and Serratia epidermidis. 2-Chloro-3',4'-dihydroxyacetophenone inhibits the production of reactive oxygen species (ROS) by inhibiting lipid peroxidation in human liver cells and it has also been shown to have antiradical activity.