3,5-Difluorobenzenethiol, with the CAS number 99389-26-1, is an organofluorine compound characterized by the presence of two fluorine atoms and a thiol (-SH) group attached to a benzene ring. This compound features a benzene ring substituted at the 3 and 5 positions with fluorine atoms, which can influence its chemical reactivity and physical properties. The presence of the thiol group imparts distinct characteristics, such as the ability to form hydrogen bonds and participate in nucleophilic reactions. 3,5-Difluorobenzenethiol is typically a colorless to pale yellow liquid with a characteristic odor, and it is soluble in organic solvents. Its fluorinated structure may enhance its stability and lipophilicity compared to non-fluorinated analogs. This compound can be utilized in various applications, including as a building block in organic synthesis, in the development of pharmaceuticals, and in materials science. Safety precautions should be taken when handling this substance, as thiols can be toxic and have strong odors.

3,5-difluorobenzenethiol

99389-26-1: Benzenethiol, 3,5-difluoro-, 3,5-Difluorothiophenol

3,5-Difluorothiophenol

BENZENETHIOL, 3,5-DIFLUORO-

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Stability Volatile
Applications 3,5-Difluorothiophenol could be a useful reagent for the design and synthesis of new selective tropomyosin receptor kinase inhibitors
References Duan, Y., et al.: Eur. J. Med. Chem., 203, 112552 (2020)


CAS 99389-26-1: 3,5-difluorobenzenethiol

3,5-Difluorothiophenol

Ref: 10-F023121

BENZENETHIOL, 3,5-DIFLUORO-

Ref: IN-DA0036NH

3,5-Difluorothiophenol

Ref: 3D-FD77589

3,5-Difluorothiophenol

Ref: 54-PC5677

3,5-Difluorothiophenol

Ref: TR-D452080