CAS 99522-79-9: Pranidipine
Formula:C25H24N2O6
InChI:InChI=1/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+
InChI key:InChIKey=XTFPDGZNWTZCMF-DHZHZOJONA-N
SMILES:C(OC/C=C/C1=CC=CC=C1)(=O)C=2C(C(C(OC)=O)=C(C)NC2C)C3=CC(N(=O)=O)=CC=C3
Synonyms:- (E)-Cinnamyl methyl (+-)-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[(2E)-3-phenyl-2-propen-1-yl] ester
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (2E)-3-phenyl-2-propenyl ester
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 3-phenyl-2-propenyl ester, (E)-
- Acalas
- Brn 5654325
- Ccris 6666
- Frc 8411
- Methyl cinnamyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
- Opc 13340
- Pranidipine [INN]
- See more synonyms
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Found 4 products.
Pranidipine
CAS:Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.Formula:C25H24N2O6Purity:99.89%Color and Shape:Yellow SolidMolecular weight:448.47Pranidipine
CAS:Applications A novel calcium channel antagonist; cardiovascular agent. References Matsumori, A., et al.: Circulation, 66, 355 (1982), Roberts, W., et al.: Am. J. Cardiol., 60, 1340 (1987), Uehara, Y., et al.: J. Cardiovasc. Pharmacol., 23, 970 (1994), Kim, C., et al.: Cardiovasc. Drugs Ther., 13, 455 (1999), Watanabe, K., et al.: Br. J. Pharmacol., 130, 1489 (2000),Formula:C25H24N2O6Color and Shape:NeatMolecular weight:448.47Pranidipine
CAS:Pranidipine is a calcium channel blocker and a positive inotrope. It is used for the treatment of high blood pressure, as well as chronic heart failure. Pranidipine also inhibits the action of cyclase, which is an enzyme that catalyzes the formation of cAMP from ATP. This drug may be used to treat pain due to bowel disease by blocking voltage-dependent calcium channels on neurons in the intestine. The reaction mechanism of pranidipine is inhibition of cyclase, but it also inhibits other enzymes such as phosphodiesterases and lipoxygenases. Significant interactions with other drugs have been observed using rat studies. Pranidipine has been shown to decrease glomerular filtration rate and renal clearance, leading to toxicity in rats at high doses. This drug also causes cardiac arrhythmia, drug interactions, and liver damage at higher doses.Formula:C25H24N2O6Purity:Min. 95%Molecular weight:448.47 g/mol
