Glucagon-like peptide-1 (GLP-1) fragment 1-36 amide is a peptide hormone that plays a crucial role in glucose metabolism and appetite regulation. It is derived from the proglucagon gene and is primarily secreted by the intestinal L-cells in response to food intake. This peptide is known for its ability to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, thereby helping to lower blood glucose levels. Additionally, GLP-1 inhibits glucagon release, slows gastric emptying, and promotes satiety, making it a target for diabetes treatment and obesity management. The amide form indicates that the C-terminus of the peptide is amidated, which can enhance its stability and biological activity. GLP-1 and its analogs are utilized in therapeutic applications, particularly in the treatment of type 2 diabetes, due to their beneficial effects on glycemic control and weight loss. The CAS number 99658-04-5 specifically identifies this peptide, facilitating its recognition in scientific literature and regulatory contexts.

glucagon-like peptide I fragment 1-36*amide human

99658-04-5: Glucagon-Like Peptide 1 amide (human), H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat)

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CAS 99658-04-5: glucagon-like peptide I fragment 1-36*amide human

GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat)

Ref: 01-4030651

GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt

Ref: 3D-FG109695