CAS 998-39-0: Tri-n-butylgermanium

Tributylgermanium hydride is a monomeric organometallic compound that is used in the synthesis of cationic polymers. It is an enzyme inhibitor that can be used to modulate protein interactions with DNA. Tributylgermanium hydride has been shown to inhibit the polymerization of epoxide-functionalized olefins and form cross-linked networks. This product also has anti-inflammatory properties due to its inhibition of prostaglandin synthesis. Tributylgermanium hydride has been shown to be capable of reducing or catalyzing the rate of chemical reactions, such as radical coupling, electrochemical methods, and silicon surface modification.

Germanium-Base Reducing Agent Tri-n-butylgermane; Tributylgermanium hydride Reduces acid chlorides to aldehydes in presence of Pd(0)Effects free-radical reductive addition of alkyl halides to olefinsReduces benzylic chlorides 70x faster than silyl hydrides

Tri-n-butylgermanium hydride is used in the reduction of benzylic chlorides. It is also used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.