EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Products of "EGFR"
Sort by
AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.Formula:C16H14ClN3O2Purity:99.03% - 99.71%Color and Shape:SolidMolecular weight:315.75EGFR-IN-147
CAS:EGFR-IN-147 (compound ID-5841161) is a potent EGFR inhibitor, demonstrating a 14% inhibition rate at a concentration of 1μM. It holds promise for cancer research applications.Formula:C13H13N5OColor and Shape:SolidMolecular weight:255.275Neratinib
CAS:Formula:C30H29ClN6O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:557.05Tyrphostin A1
CAS:Formula:C11H8N2OPurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:184.20Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formula:C32H36N8O3Purity:98.12% - 98.12%Color and Shape:SolidMolecular weight:580.68WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.6%Color and Shape:SolidMolecular weight:376.2Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormula:C23H25ClFN5O3Purity:98.89% - 99.83%Color and Shape:SolidMolecular weight:473.93Alflutinib
CAS:Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.Formula:C28H31F3N8O2Purity:99.61%Color and Shape:SolidMolecular weight:568.59Ref: TM-T22254
1mg213.00€5mg435.00€10mg620.00€25mg938.00€50mg1,320.00€100mg1,786.00€1mL*10mM (DMSO)560.00€EGFR-IN-128
EGFR-IN-128 (compound 28) is a potent and selective molecule targeting wild-type EGFREx20Ins, demonstrating therapeutic efficacy across various human xenograft models and capable of penetrating the blood-brain barrier in preclinical species.Formula:C27H20N4OColor and Shape:SolidMolecular weight:416.47Nezutatug
CAS:Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].Purity:98%Color and Shape:LiquidBPI-15086
CAS:BPI-15086 is an orally active, effective, irreversible inhibitor selective for mutations, targeting both EGFR and the T790M resistance mutation tyrosine kinase. It can be utilized in the study of non-small cell lung cancer.Formula:C29H33ClN8O4Color and Shape:SolidMolecular weight:593.08FRF-06-057
FRF-06-057 is an allosteric ATP EGFR inhibitor targeting both wild-type and mutant EGFR, with IC50 values of 17 nM (LR/TM), 29 nM (LR/TM/CS), 220 nM (LR), and >1000 nM (WT).Formula:C19H13N3O3SColor and Shape:SolidMolecular weight:363.39Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formula:C10H7NO4Purity:99.02%Color and Shape:SolidMolecular weight:205.17Labuxtinib
CAS:Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].Formula:C20H16FN5O2Purity:99.77%Color and Shape:SolidMolecular weight:377.37Ref: TM-T79851
1mg139.00€5mg338.00€10mg540.00€25mg1,074.00€50mg1,549.00€100mg2,080.00€200mg2,802.00€1mL*10mM (DMSO)374.00€Anti-EGFR Monoclonal Antibody-AF488
Anti-EGFR Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting EGFR. Anti-EGFR Monoclonal Antibody-AF488 can be used in FACS.Purity:> 95% as determined by SDS-PAGE.Color and Shape:LiquidMolecular weight:150 kDaDacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purity:100% - 99.72%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2483
1mg38.00€2mg49.00€5mg79.00€10mg127.00€25mg173.00€50mg227.00€100mg354.00€200mg444.00€500mg730.00€1mL*10mM (DMSO)79.00€Rezivertinib
CAS:Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.Formula:C27H30N6O3Purity:99.43% - 99.89%Color and Shape:SolidMolecular weight:486.57Ref: TM-T36644
1mg99.00€5mg226.00€10mg364.00€25mg702.00€50mg947.00€100mg1,264.00€200mg1,700.00€1mL*10mM (DMSO)47.00€JH-XI-10-02
CAS:JH-XI-10-02 selectively degrades CDK8 (IC50: 159 nM) through proteasome, sparing CDK8 mRNA and CDK19.Formula:C53H69N5O9Purity:98%Color and Shape:SolidMolecular weight:920.161
