EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Products of "EGFR"
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Depatuxizumab MMAF
Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized in glioblastoma research.Color and Shape:LiquidMolecular weight:148.24 kDaCP-724714
CAS:CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2Formula:C27H27N5O3Purity:97.10% - 98.82%Color and Shape:SolidMolecular weight:469.54Ref: TM-T4014
1mg44.00€2mg58.00€5mg95.00€10mg157.00€25mg273.00€50mg454.00€100mg660.00€1mL*10mM (DMSO)89.00€EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Formula:C19H15N3O2SPurity:100%Color and Shape:SolidMolecular weight:349.41Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.53%Color and Shape:SolidMolecular weight:554.64Self-assembling peptide pY1
Self-assembling peptide pY1, which aggregates around cancer cells, specifically targets the EGFR receptor. When co-cultured with Ovalbumin (OVA), pY1 effectively inhibits the endocytosis of OVA.Formula:C104H125N24O29PColor and Shape:SolidMolecular weight:2206.22EGFR Protein, Rhesus macaque, Recombinant (His)
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Color and Shape:Lyophilized PowderMolecular weight:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.YS-363
CAS:YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (Formula:C30H30N4O3Purity:98%Color and Shape:SolidMolecular weight:494.58EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37JGK-068S
CAS:Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].Formula:C22H23BrFN5O2Purity:98%Color and Shape:SolidMolecular weight:488.35Tyrphostin AG 1478
CAS:Formula:C16H14ClN3O2Purity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:315.762H-1-Benzopyran-2-one, 7,8-dihydroxy-
CAS:Formula:C9H6O4Purity:90%Color and Shape:SolidMolecular weight:178.1415EGFR-IN-7
CAS:EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.Formula:C32H41BrN9O2PPurity:95.32% - 99.64%Color and Shape:SolidMolecular weight:694.6Chalcone
CAS:Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively asFormula:C15H12OPurity:97.27%Color and Shape:SolidMolecular weight:208.26Pelitinib
CAS:Formula:C24H23ClFN5O2Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:467.93ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05%Color and Shape:SolidMolecular weight:367.91Tesevatinib tosylate
CAS:Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.Formula:C31H33Cl2FN4O5SColor and Shape:SolidMolecular weight:663.59EGFR-IN-5
CAS:EGFR-IN-5 inhibits EGFR & mutants; IC50: EGFR 10.4nM, L858R 1.1nM, L858R/T790M 34nM, L858R/T790M/C797S 7.2nM.Formula:C31H38FN9OPurity:98.17%Color and Shape:SolidMolecular weight:571.69Intetumumab
CAS:Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.Color and Shape:LiquidMolecular weight:145.6 (kDa)Desmethyl Erlotinib
CAS:Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).Formula:C21H21N3O4Purity:97.92% - 98.62%Color and Shape:SolidMolecular weight:379.41Ref: TM-T6328
1mg52.00€2mg77.00€5mg115.00€10mg188.00€25mg331.00€50mg497.00€100mg720.00€1mL*10mM (DMSO)127.00€RTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Formula:C24H22ClF3N2O3SPurity:98.14%Color and Shape:SolidMolecular weight:510.96Ref: TM-T12777
5mg52.00€10mg80.00€25mg169.00€50mg284.00€100mg411.00€500mg867.00€1mL*10mM (DMSO)59.00€
