Syk
Syk (spleen tyrosine kinase) inhibitors are compounds that target Syk, a kinase involved in immune cell signaling and the regulation of angiogenesis. Syk plays a role in the inflammatory responses that can contribute to tumor angiogenesis. Inhibiting Syk can reduce inflammation-induced blood vessel formation in tumors, making these inhibitors valuable in cancer therapy and inflammation research. At CymitQuimica, we offer a diverse range of high-quality Syk inhibitors to support your research in immunology, oncology, and angiogenesis.
Products of "Syk"
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Found 35 products on this category.
MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16Piceatannol
CAS:Formula:C14H12O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light red powder to crystalMolecular weight:244.25PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurity:98.82%Color and Shape:SolidMolecular weight:340.42Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Formula:C23H25N9OPurity:98.35%Color and Shape:SolidMolecular weight:443.5Ref: TM-T11824LL
1mg51.00€2mg74.00€5mg99.00€10mg167.00€25mg290.00€50mg430.00€100mg633.00€1mL*10mM (DMSO)115.00€BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFormula:C20H18N6O3Purity:98.94%Color and Shape:SolidMolecular weight:390.4Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formula:C14H15F3N6OPurity:97.63%Color and Shape:SolidMolecular weight:340.31,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Formula:C9H7NO4Purity:98%Color and Shape:SolidMolecular weight:193.1562RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Formula:C18H25N7OPurity:97.19%Color and Shape:SolidMolecular weight:355.44Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.23%Color and Shape:SolidMolecular weight:482Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg44.00€2mg55.00€5mg79.00€10mg106.00€25mg185.00€50mg283.00€100mg432.00€200mg605.00€500mg938.00€1mL*10mM (DMSO)86.00€Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Formula:C26H31N9O4Purity:98%Color and Shape:SolidMolecular weight:533.58Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purity:97.53% - 98.63%Color and Shape:SolidMolecular weight:450.39Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurity:96.13% - 98.95%Color and Shape:SolidMolecular weight:624.42Ref: TM-T2605
1mg47.00€2mg55.00€5mg88.00€10mg124.00€25mg221.00€50mg374.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)116.00€OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Formula:C27H35N7O9S2Purity:96.16%Color and Shape:SolidMolecular weight:665.741,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Formula:C14H12O4Purity:98%Color and Shape:SolidMolecular weight:244.2427TC-S 7003
CAS:TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.Formula:C31H30N8OPurity:99.74%Color and Shape:SolidMolecular weight:530.62Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formula:C14H12O4Purity:98.66% - 99.57%Color and Shape:Light Tan To Yellow PowderMolecular weight:244.24R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Formula:C22H23FN6O5Purity:97.64% - 99.11%Color and Shape:SolidMolecular weight:470.45Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formula:C23H26FN6O9PPurity:93.08% - 99.38%Color and Shape:SolidMolecular weight:580.46Ref: TM-T6115
1mg43.00€2mg57.00€5mg88.00€10mg118.00€25mg210.00€50mg335.00€100mg548.00€500mg1,198.00€1mL*10mM (DMSO)101.00€Entospletinib
CAS:Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.Formula:C23H21N7OPurity:98.2% - 99.51%Color and Shape:SolidMolecular weight:411.46Ref: TM-T6101
1mg38.00€2mg49.00€5mg81.00€10mg97.00€25mg170.00€50mg259.00€100mg416.00€200mg617.00€1mL*10mM (DMSO)88.00€Syk-IN-8
CAS:Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.Formula:C23H26N10Purity:98%Color and Shape:SolidMolecular weight:442.52Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formula:C24H28N8O2Purity:98.06% - 99.94%Color and Shape:SolidMolecular weight:460.53Ref: TM-T14331
1mg42.00€5mg88.00€10mg123.00€25mg188.00€50mg350.00€100mg522.00€200mg750.00€1mL*10mM (DMSO)116.00€R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purity:99.06% - 99.84%Color and Shape:SolidMolecular weight:312.3Ref: TM-T3185
1mg39.00€2mg51.00€5mg84.00€10mg124.00€25mg219.00€50mg329.00€100mg487.00€500mg1,026.00€1mL*10mM (DMSO)92.00€Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formula:C58H68N18O14Color and Shape:SolidMolecular weight:1241.294Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Formula:C27H31N9O5Purity:98%Color and Shape:SolidMolecular weight:561.59Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurity:99.94%Color and Shape:SolidMolecular weight:217.65TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurity:99.46%Color and Shape:SolidMolecular weight:463.32Ref: TM-T6776
1mg38.00€5mg84.00€10mg116.00€25mg187.00€50mg279.00€100mg406.00€200mg565.00€1mL*10mM (DMSO)87.00€PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formula:C19H23N9O·HClPurity:97.11% - 99.93%Color and Shape:SolidMolecular weight:429.91Ref: TM-T2696
1mg60.00€2mg86.00€5mg127.00€10mg187.00€25mg326.00€50mg500.00€200mg948.00€1mL*10mM (DMSO)139.00€ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFormula:C20H22N2O5Purity:98%Color and Shape:SolidMolecular weight:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Formula:C24H30N6O3SPurity:98.51%Color and Shape:SolidMolecular weight:482.6Ref: TM-T32088
1mg127.00€5mg305.00€10mg459.00€25mg777.00€50mg1,216.00€100mg1,890.00€200mg2,547.00€1mL*10mM (DMSO)324.00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formula:C22H23FN6O5·C6H6O3SPurity:97.67% - 98.82%Color and Shape:SolidMolecular weight:628.63Ref: TM-T6174
1mg48.00€2mg60.00€5mg94.00€10mg150.00€25mg316.00€50mg470.00€100mg683.00€1mL*10mM (DMSO)127.00€Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.Formula:C24H28N4O3SPurity:100% - 97.99%Color and Shape:SolidMolecular weight:452.57MNS
CAS:Formula:C9H7NO4Purity:>98.0%(GC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:193.16
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