Thrombin
Thrombin inhibitors are compounds that block thrombin, an enzyme involved in the blood coagulation process that also has a role in promoting angiogenesis. Thrombin can stimulate the formation of new blood vessels in tumors, aiding in their growth and metastasis. By inhibiting thrombin, these compounds can reduce angiogenesis and tumor progression. Thrombin inhibitors are important in both cancer research and the study of vascular diseases. At CymitQuimica, we provide a selection of high-quality thrombin inhibitors to support your research in hemostasis, oncology, and angiogenesis.
Products of "Thrombin"
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Ozagrel hydrochloride
CAS:Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contractionFormula:C13H12N2O2·HClPurity:99.80%Color and Shape:White Or Off White Crystalline PowderMolecular weight:264.71Protamine sulfate
CAS:Protamine sulfate: polycationic peptide, antiheparin, neutralizes anticoagulant effect, aids gene transfer.Purity:98%Color and Shape:SolidNQ301
CAS:NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).Formula:C18H12ClNO3Purity:99.76% - 99.81%Color and Shape:SolidMolecular weight:325.75Naroparcil
CAS:Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.Formula:C19H17NO4S2Purity:98.11% - 99%Color and Shape:SolidMolecular weight:387.47AEBSF hydrochloride
CAS:AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.Formula:C8H11ClFNO2SPurity:98% - 99.61%Color and Shape:White PowderMolecular weight:239.69Pirodomast
CAS:Pirodomast is a thromboxane A (TXA2) synthase inhibitor.Formula:C18H17N3O2Purity:99.34%Color and Shape:SolidMolecular weight:307.35SCH79797 dihydrochloride
CAS:SCH79797 dihydrochloride is a PAR1 antagonist with IC50 70 nM, Ki 35 nM, antiproliferative, and pro-apoptotic properties.Formula:C23H27Cl2N5Purity:98.58%Color and Shape:SolidMolecular weight:444.4Argatroban Monohydrate
CAS:Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.Formula:C23H38N6O6SPurity:99.51%Color and Shape:SolidMolecular weight:526.65Anti-Coagulation Factor II Antibody (8M286)
Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA.Color and Shape:Odour LiquidDabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Formula:C25H25N7O3Purity:97.44% - 98.70%Color and Shape:Tan SolidMolecular weight:471.51OM-189
CAS:OM-189 is a selective inhibitor of synthetic thrombin.Formula:C24H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:488.65NFPS
CAS:NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.Formula:C24H24FNO3Purity:98%Color and Shape:SolidMolecular weight:393.45Thrombin (MW 37kDa)
CAS:Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Purity:98%Color and Shape:SolidMolecular weight:37kDaLK-732
CAS:LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.Formula:C25H29N5O3SColor and Shape:SolidMolecular weight:479.59Thrombin inhibitor 1
CAS:Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).Formula:C22H20Cl2F2N4O3Purity:98%Color and Shape:SolidMolecular weight:497.32p-Hydroxycinnamic acid
CAS:p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-inducedFormula:C9H8O3Purity:99.67%Color and Shape:SolidMolecular weight:164.16Avatrombopag
CAS:Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiationFormula:C29H34Cl2N6O3S2Purity:99.01% - 99.41%Color and Shape:SolidMolecular weight:649.65Ref: TM-T7417
1mg59.00€5mg120.00€10mg187.00€25mg339.00€50mg567.00€100mg810.00€200mg1,111.00€1mL*10mM (DMSO)170.00€DS-1040 Tosylate
CAS:DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.Formula:C23H35N3O5SColor and Shape:SolidMolecular weight:465.61Odiparcil
CAS:Odiparcil is an orally active beta-d-thioxyloside analog.Formula:C15H16O6SPurity:98%Color and Shape:SolidMolecular weight:324.35Dermatan sulphate sodium
CAS:Dermatan sulphate sodium (Chondroitin sulfate B sodium salt) is a linear sulfated polysaccharide, a glycosaminoglycan component of several important proteoglycans, and an activating ligand for the kinase of mesenchymal lymphoma. Dermatan sulphate sodium is an anticoagulant, inhibiting thrombus Dermatan sulphate sodium is an anticoagulant that inhibits thrombosis.Color and Shape:SolidCoagulation Factor II Protein, Rat, Recombinant (His)
Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:69.5 kDa (predicted)Eltrombopag Olamine
CAS:Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietinFormula:C29H36N6O6Purity:99.59% - 99.89%Color and Shape:SolidMolecular weight:564.63Ref: TM-T6825
2mg43.00€5mg64.00€10mg90.00€25mg140.00€50mg177.00€100mg230.00€200mg340.00€500mg563.00€1mL*10mM (DMSO)90.00€Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purity:98%Color and Shape:SolidMolecular weight:1322Ozagrel
CAS:Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement ofFormula:C13H12N2O2Purity:97.90% - 99.38%Color and Shape:White PowderMolecular weight:228.25Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purity:99.86% - 99.91%Color and Shape:SolidMolecular weight:738.27Melagatran
CAS:Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.Formula:C22H31N5O4Purity:100% - 98.37%Color and Shape:SolidMolecular weight:429.51Ref: TM-T11994
1mg513.00€5mg1,198.00€10mg1,549.00€25mg2,337.00€50mg3,125.00€100mg4,246.00€1mL*10mM (DMSO)1,130.00€Cycloolivil
CAS:Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees.Formula:C20H24O7Purity:98%Color and Shape:SolidMolecular weight:376.4Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formula:C34H41N7O5Purity:98.19% - 99.12%Color and Shape:White PowderMolecular weight:627.73Anti-Coagulation Factor II Antibody (2P591)
Anti-Coagulation Factor II Antibody (2P591) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (2P591) can be used in WB.Color and Shape:Odour LiquidZ-Gly-Pro-Arg-4MβNA
CAS:Z-Gly-Pro-Arg-4MβNA is a thrombin substrate that, upon cleavage by thrombin, releases 4-methoxy-2-naphthylamine (4MβNA).Formula:C32H39N7O6Purity:98%Color and Shape:SolidMolecular weight:617.7Efegatran sulfate
CAS:Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.Formula:C21H34N6O7SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:514.6Dabigatran Etexilate Mesylate
CAS:Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.Formula:C34H41N7O5·CH4O3SPurity:99.91%Color and Shape:SolidMolecular weight:723.84Ref: TM-T5133
5mg42.00€10mg57.00€25mg74.00€50mg95.00€100mg111.00€200mg169.00€500mg240.00€1mL*10mM (DMSO)64.00€Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Dabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purity:97.63%Color and Shape:SolidMolecular weight:499.56H-D-Phe-Pip-Arg-pNA dihydrochloride
CAS:H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238) is a sensitive and accurate thrombin detection substrate for measuring antithrombin-heparin cofactor (AT-III).Formula:C27H38Cl2N8O5Purity:99.47%Color and Shape:SolidMolecular weight:625.55Ref: TM-T40711
1mg170.00€5mg346.00€10mg515.00€25mg833.00€50mg1,121.00€100mg1,539.00€1mL*10mM (DMSO)655.00€Menadione
CAS:Menadione (Vitamin K3) is a synthetic naphthoquinone, inactive but converts to active Vitamin K2 in vivo.Formula:C11H8O2Purity:99.08% - 99.41%Color and Shape:Bright Yellow Crystals SolidMolecular weight:172.18Hirudin
CAS:Hirudin is an anticoagulant extracted from leeches, a thrombin inhibitor, used in diabetic nephropathy research.Formula:C66H93N13O25Purity:99.75%Color and Shape:SolidMolecular weight:1468.52Ref: TM-T126366
1mg180.00€5mg449.00€10mg655.00€25mg1,026.00€50mg1,388.00€100mg1,872.00€200mg2,527.00€Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formula:C27H30ClN7O3Purity:99.65%Color and Shape:SolidMolecular weight:536.03Heparin
CAS:Heparin (Adomiparin) is a mucopolysaccharide sulfate that has shown partial anti-inflammatory activity in in vivo studies.Formula:C26H42N2O37S5Purity:98%Color and Shape:White Or Pale-Colored Amorphous Powder SolidMolecular weight:1134.9NP-313
CAS:NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.Formula:C12H8ClNO3Purity:98.97%Color and Shape:SolidMolecular weight:249.65Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H38FN3O5Purity:98.25% - 98.5%Color and Shape:SolidMolecular weight:527.63Flovagatran
CAS:Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.Formula:C27H36BN3O7Purity:99.56%Color and Shape:SolidMolecular weight:525.4Bivalirudin
CAS:Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clottingFormula:C98H138N24O33Purity:100.00% - 98.8%Color and Shape:White To Off-White PowderMolecular weight:2180.29Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurity:99.96%Color and Shape:SolidMolecular weight:591.55Ref: TM-TQ0223
1mg74.00€2mg96.00€5mg165.00€10mg255.00€25mg492.00€50mg715.00€100mg1,008.00€1mL*10mM (DMSO)208.00€Metolazone
CAS:Metolazone (SR-720-22) is a quinazoline-sulfonamide derived diuretic that inhibits sodium chloride symporters.Formula:C16H16ClN3O3SPurity:98.14% - 98.5%Color and Shape:Crystals From Ethanol SolidMolecular weight:365.83MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16Imitrodast
CAS:Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, andFormula:C13H12N2O2SPurity:98.04%Color and Shape:SolidMolecular weight:260.31Argatroban
CAS:Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.Formula:C23H36N6O5SPurity:100% - 99.77%Color and Shape:White To Off-White Crystalline SolidMolecular weight:508.63Ref: TM-T0155
5mg39.00€10mg59.00€25mg103.00€50mg160.00€100mg235.00€200mg349.00€500mg567.00€1mL*10mM (DMSO)52.00€Coagulation Factor II Protein, Mouse, Recombinant (His)
Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:69.3 kDa (predicted); 85 kDa (reducing conditions)Ximelagatran
CAS:Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.Formula:C24H35N5O5Purity:95.48% - 98.09%Color and Shape:SolidMolecular weight:473.57
