TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Products of "TNF"
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Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Purity:95% - 95%Color and Shape:LiquidCot inhibitor-1
CAS:Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Formula:C27H27Cl2FN8Purity:99.19%Color and Shape:SolidMolecular weight:553.46Ref: TM-T10865
1mg81.00€5mg169.00€10mg246.00€25mg445.00€50mg655.00€100mg998.00€200mg1,349.00€1mL*10mM (DMSO)197.00€Dapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Color and Shape:LiquidMolecular weight:145.5 kDaBMS-561392
CAS:BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.Formula:C27H32N4O4Purity:99.16%Color and Shape:SolidMolecular weight:476.57Siegeskaurolic acid
CAS:Siegeskaurolic acid reduces inflammation and pain by blocking iNOS and COX-2 in macrophages via NF-kappaB inactivation.Formula:C20H32O3Purity:98%Color and Shape:SolidMolecular weight:320.47Trovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formula:C21H19F3N4O6SPurity:99.12%Color and Shape:SolidMolecular weight:512.46Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.73%Color and Shape:White PowderMolecular weight:354.31Hispidol
CAS:Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Ref: TM-T4319
1mg44.00€2mg59.00€5mg87.00€10mg144.00€25mg212.00€50mg274.00€100mg432.00€200mg590.00€500mg1,008.00€1mL*10mM (DMSO)97.00€α-Humulene
CAS:α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatoryFormula:C15H24Purity:97.18% - 97.18%Color and Shape:LiquidMolecular weight:204.35RO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Color and Shape:Odour LiquidConatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145 kDa (average)Linarin
CAS:Linarin inhibits acetylcholinesterase, reduces liver injury via TNF-α, protects neurons via PI3K/Akt, and has enhanced absorption with piperine.Formula:C28H32O14Purity:97.95% - 98.99%Color and Shape:White To Off White PowderMolecular weight:592.557,3',4'-Tri-O-methylluteolin
CAS:7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).Formula:C18H16O6Purity:98.66% - 98.99%Color and Shape:SolidMolecular weight:328.32Ref: TM-TN1291
1mg87.00€5mg170.00€10mg264.00€25mg452.00€50mg647.00€100mg900.00€1mL*10mM (DMSO)187.00€Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%Color and Shape:LiquidMolecular weight:38.44 kDaSTING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Formula:C15H16N2O4Purity:98.61%Color and Shape:SolidMolecular weight:288.3TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formula:C16H16N6OPurity:98.44%Color and Shape:SolidMolecular weight:308.34Ref: TM-T8692
1mg73.00€5mg124.00€10mg187.00€25mg376.00€50mg562.00€100mg802.00€500mg1,644.00€1mL*10mM (DMSO)137.00€Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formula:C82H134O43Purity:99.49% - 99.69%Color and Shape:SolidMolecular weight:1807.92GSK2593074A
CAS:GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Formula:C27H23N5OSPurity:100%Color and Shape:SolidMolecular weight:465.57Ref: TM-T11484
1mg114.00€5mg274.00€10mg432.00€25mg725.00€50mg1,017.00€100mg1,359.00€1mL*10mM (DMSO)303.00€Selicrelumab
CAS:Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Purity:95% - 95%Color and Shape:LiquidAdalimumab
CAS:Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.Purity:95% - 99.50%Color and Shape:LiquidMolecular weight:145.4 kDaNodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Formula:C14H13N3O2SPurity:99.97% - 99.98%Color and Shape:SolidMolecular weight:287.34TNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purity:98.28%Color and Shape:SoildMolecular weight:282.29Teneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Purity:95.00% - 99.19% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.06 kDaAstilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Formula:C21H22O11Purity:97% - 99.76%Color and Shape:White PowderMolecular weight:450.39Ref: TM-T2794
5mg52.00€10mg77.00€25mg140.00€50mg224.00€100mg334.00€200mg477.00€500mg778.00€1mL*10mM (DMSO)51.00€Sinensetin
CAS:Sinensetin, a citrus flavone, has antiangiogenic, anti-inflammatory properties, and promotes fat formation and breakdown.Formula:C20H20O7Purity:97.74% - 99.33%Color and Shape:Pale Creamy Yellow PowderMolecular weight:372.37Zigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Color and Shape:LiquidSciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.14% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg52.00€5mg95.00€10mg162.00€25mg304.00€50mg455.00€100mg653.00€500mg1,349.00€1mL*10mM (DMSO)130.00€UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Formula:C11H8Cl2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:271.1Ref: TM-T8845
1mg50.00€5mg105.00€10mg164.00€25mg321.00€50mg452.00€100mg645.00€200mg868.00€1mL*10mM (DMSO)129.00€CDC801
CAS:CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.Formula:C23H24N2O5Purity:98.81%Color and Shape:SolidMolecular weight:408.45Lucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Purity:95% - 95%Color and Shape:LiquidTNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Color and Shape:Lyophilized PowderMolecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purity:SDS-PAGE:95.2%;SEC-HPLC:98.5%Color and Shape:LiquidMolecular weight:142.77 kDacRIPGBM
CAS:cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Formula:C26H20FN2O2Purity:98%Color and Shape:SolidMolecular weight:411.45Homovanillyl alcohol
CAS:Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol.Formula:C9H12O3Purity:99.62%Color and Shape:Cream To Light Brown ChunksMolecular weight:168.19Brentuximab
CAS:Brentuximab is a chimeric antibody targeting CD30 and is a naked antibody to Brentuximab vedotin.Brentuximab has antitumor activity and may be used to studyPurity:95% - 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.21 kDaGiloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Purity:95% - 95%Color and Shape:LiquidTigatuzumab
CAS:Tigatuzumab (CS-1008) is a humanized monoclonal antibody targeting DR5 and is a TRAIL-R2 agonist with antitumor activity that induces apoptosis in cancer cells.Purity:95% - 95%Color and Shape:LiquidMolecular weight:144.6 (kDa)HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormula:C22H22O11Purity:97.63% - 99.66%Color and Shape:SolidMolecular weight:462.4Ref: TM-T4S0217
5mg50.00€10mg74.00€25mg140.00€50mg226.00€100mg324.00€200mg464.00€1mL*10mM (DMSO)52.00€IA-14069
CAS:IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.Formula:C20H15ClF2O4Color and Shape:SoildMolecular weight:392.78R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurity:98.64%Color and Shape:SolidMolecular weight:380.77Ref: TM-T4637
2mg46.00€5mg66.00€10mg96.00€25mg207.00€50mg283.00€100mg464.00€500mg1,008.00€1mL*10mM (DMSO)74.00€Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.Formula:C27H28Cl3FN8Purity:98.26%Color and Shape:SoildMolecular weight:589.92Ref: TM-T10865L
1mg125.00€5mg240.00€10mg379.00€25mg632.00€50mg899.00€100mg1,216.00€1mL*10mM (DMSO)283.00€Drozitumab
CAS:Drozitumab (PRO 95780) is a fully humanized antibody targeting the death receptor DR5 for the study of triple-negative breast cancer.Purity:95% - 95%Color and Shape:LiquidMolecular weight:143.1 (kDa)Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purity:>95%Color and Shape:LiquidTNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Purity:98% - > 99.9%Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Formula:C22H28O11Purity:98.57% - 99.92%Color and Shape:SolidMolecular weight:468.45Cetrelimab
CAS:Cetrelimab (JNJ 63723283) is a humanized monoclonal antibody targeting PD-1, useful in research on multiple myeloma and bladder cancer.Purity:>95%Color and Shape:LiquidTulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Color and Shape:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Purity:95% - ＞10mg/mlColor and Shape:Odour LiquidGolimumab
CAS:Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used to prevent inflammation and cartilage.Color and Shape:LiquidMolecular weight:146.93 kDa
