p53
p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.
Products of "p53"
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Found 75 products on this category.
UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Formula:C36H59N7O2Purity:100%Color and Shape:SolidMolecular weight:621.9UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Formula:C37H61N7O2Purity:98.76%Color and Shape:SolidMolecular weight:635.93NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderAmifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Anti-p53 Antibody (9D896)
Anti-p53 Antibody (9D896) is an antibody targeting p53. Anti-p53 Antibody (9D896) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidDPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Formula:C24H14N2O2Purity:98.73%Color and Shape:SolidMolecular weight:362.38Ref: TM-T11092
1mg105.00€2mg158.00€5mg259.00€10mg374.00€25mg562.00€50mg775.00€100mg1,035.00€500mgTo inquireAnti-p53 Antibody (2V863)
Anti-p53 Antibody (2V863) is a Mouse antibody targeting p53. Anti-p53 Antibody (2V863) can be used in ELISA,ELISA(Det).Color and Shape:Odour LiquidNSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Formula:C38H40N10Purity:98.69% - 99.91%Color and Shape:SolidMolecular weight:636.79Ref: TM-T6909
2mg42.00€5mg62.00€10mg96.00€25mg180.00€50mg296.00€100mg427.00€500mg938.00€1mL*10mM (DMSO)85.00€Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
CAS:Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFormula:C22H16N2OPurity:99.18%Color and Shape:SolidMolecular weight:324.38Ref: TM-T9129
1mg52.00€5mg107.00€10mg158.00€25mg259.00€50mg374.00€100mg523.00€200mg710.00€1mL*10mM (DMSO)111.00€cjoc42
CAS:Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.Formula:C20H21N3O5SPurity:98.54%Color and Shape:SolidMolecular weight:415.46Ref: TM-T27029
1mg64.00€5mg140.00€10mg205.00€25mg368.00€50mg552.00€100mg770.00€200mg1,035.00€1mL*10mM (DMSO)160.00€Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purity:98.7%Color and Shape:SolidMolecular weight:377.01KCC-07
CAS:KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.Formula:C14H11N3OSPurity:98.86% - 99.01%Color and Shape:SolidMolecular weight:269.32Ref: TM-T8554
1mg40.00€2mg52.00€5mg79.00€10mg124.00€25mg235.00€50mg374.00€100mg555.00€500mg1,206.00€1mL*10mM (DMSO)82.00€Tetrofosmin
CAS:Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.Formula:C18H40O4P2Color and Shape:SolidMolecular weight:382.46Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormula:C23H30CLN3O·2HClPurity:98.24% - 99.72%Color and Shape:Yellow Crystals Or PowderMolecular weight:472.88Lumichrome
CAS:Lumichrome, a riboflavin metabolite, influences plant growth, ascidian metamorphosis, bacterial communication, and blocks riboflavin uptake.Formula:C12H10N4O2Purity:99.65% - 99.69%Color and Shape:SolidMolecular weight:242.23P53R3
CAS:P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53Formula:C32H35Cl2N5O2Purity:97.75%Color and Shape:SolidMolecular weight:592.56Unesbulin
CAS:Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).Formula:C19H13F5N6Purity:98.71%Color and Shape:SolidMolecular weight:420.34YK-3-237
CAS:YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFormula:C19H21BO7Purity:99.47%Color and Shape:SolidMolecular weight:372.18Ref: TM-T9320
2mg40.00€5mg60.00€10mg87.00€25mg180.00€50mg305.00€100mg535.00€200mg690.00€500mg1,074.00€1mL*10mM (DMSO)66.00€XI-006
CAS:NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.Formula:C11H13N5O4Purity:99.12%Color and Shape:SolidMolecular weight:279.25Ref: TM-T6610
1mg56.00€2mg81.00€5mg119.00€10mg187.00€25mg432.00€50mg638.00€100mg908.00€500mg1,825.00€1mL*10mM (DMSO)114.00€Anti-p53 Antibody (8M251)
Anti-p53 Antibody (8M251) is an antibody targeting p53. Anti-p53 Antibody (8M251) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidUNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Formula:C26H43N7O2Purity:99.58%Color and Shape:SolidMolecular weight:485.67Ref: TM-T17203
1mg51.00€2mg73.00€5mg97.00€10mg159.00€25mg354.00€50mg558.00€100mg797.00€500mg1,634.00€1mL*10mM (DMSO)107.00€HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderXL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Formula:C48H57ClN8O5Purity:98.75%Color and Shape:SolidMolecular weight:861.47Ref: TM-T9122
1mg96.00€5mg187.00€10mg298.00€25mg507.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)283.00€Anti-Phospho-TP53 (Ser392) Antibody (7W136)
Anti-Phospho-TP53 (Ser392) Antibody (7W136) is an antibody targeting Phospho-TP53 (Ser392). Anti-Phospho-TP53 (Ser392) Antibody (7W136) can be used in ELISA, WB.Color and Shape:Odour LiquidAnti-p53 Antibody (2H232)
Anti-p53 Antibody (2H232) is an antibody targeting p53. Anti-p53 Antibody (2H232) can be used in ELISA, IHC.Color and Shape:Odour LiquidRezatapopt
CAS:Rezatapopt (PC14586) is a p53 reactivator with antitumor activity for the study of locally advanced or metastatic solid tumors.Formula:C28H31F4N5O2Purity:98.12%Color and Shape:SolidMolecular weight:545.57MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).Formula:C21H14N2O2Purity:97.11%Color and Shape:SolidMolecular weight:326.35Anti-p53 Antibody (3K688)
Anti-p53 Antibody (3K688) is a Rabbit antibody targeting p53. Anti-p53 Antibody (3K688) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidAnti-p53 Antibody (8C308)
Anti-p53 Antibody (8C308) is an antibody targeting p53. Anti-p53 Antibody (8C308) can be used in ELISA, WB, IF, FCM.Color and Shape:Odour LiquidNSC59984
CAS:NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.Formula:C12H15N3O4Purity:99.18% - 99.59%Color and Shape:SolidMolecular weight:265.27Ref: TM-T6910
5mg70.00€10mg107.00€25mg216.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)77.00€Anti-p53 Antibody (1J151)
Anti-p53 Antibody (1J151) is a Mouse antibody targeting p53. Anti-p53 Antibody (1J151) can be used in ELISA(Cap).Color and Shape:Odour LiquidNSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Formula:C19H13N3O7S2Purity:97.35%Color and Shape:SolidMolecular weight:459.45p53 (17-26)
CAS:Peptide is p53's amino acids 17-26, contacts Mdm-2 binding domain, also called p53N.Formula:C60H90N12O17Purity:98%Color and Shape:SolidMolecular weight:1251.43Anti-Phospho-TP53 (Thr55) Antibody (8C690)
Anti-Phospho-TP53 (Thr55) Antibody (8C690) is an antibody targeting Phospho-TP53 (Thr55). Anti-Phospho-TP53 (Thr55) Antibody (8C690) can be used in ELISA, WB, IF.Color and Shape:Odour LiquidNutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purity:95.62% - 99.71%Color and Shape:SolidMolecular weight:581.49Ref: TM-T6023
1mg49.00€2mg70.00€5mg96.00€10mg164.00€25mg268.00€50mg398.00€100mg587.00€1mL*10mM (DMSO)135.00€Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Formula:C14H19Cl2NO2Purity:97.37% - 98.45%Color and Shape:Off-White Slightly Granular Powder Melting Point 65-69°CMolecular weight:304.21C16 Ceramide
CAS:C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.Formula:C34H67NO3Purity:99.00% - 99.92%Color and Shape:White Crystalline SolidMolecular weight:537.9p53 Protein, Cynomolgus, Recombinant
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family.Color and Shape:Lyophilized PowderMolecular weight:43.7 kDa (predicted); 48 kDa (reducing conditions)Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurity:99.88%Color and Shape:White SolidMolecular weight:214.22BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purity:99.31% - 99.64%Color and Shape:SolidMolecular weight:490.64Ref: TM-T7697
1mg40.00€2mg51.00€5mg85.00€10mg117.00€25mg207.00€50mg350.00€100mg518.00€200mg740.00€1mL*10mM (DMSO)131.00€Anti-p53 Antibody (9G129)
Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.Color and Shape:Odour LiquidHLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderSCH529074
CAS:SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.Formula:C31H36Cl2N6Purity:98.71%Color and Shape:SolidMolecular weight:563.56Ref: TM-T37042
1mg35.00€2mg46.00€5mg64.00€10mg104.00€25mg220.00€50mg328.00€100mg469.00€1mL*10mM (DMSO)75.00€Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.32%Color and Shape:SolidMolecular weight:416.46Ref: TM-T6S1917
5mg71.00€10mg96.00€25mg202.00€50mg303.00€100mg452.00€500mg1,035.00€1mL*10mM (DMSO)79.00€CTX1
CAS:CTX1 is a small molecule activator of p53.Formula:C14H10N4Purity:98%Color and Shape:SolidMolecular weight:234.26PDK4-IN-1 hydrochloride
CAS:PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).Formula:C22H20ClN3O2Purity:99.54%Color and Shape:SolidMolecular weight:393.87Ref: TM-T12412L
1mg127.00€5mg300.00€10mg457.00€25mg750.00€50mg1,026.00€100mg1,406.00€500mg2,822.00€1mL*10mM (DMSO)329.00€Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formula:C29H32O13Purity:99.19% - 99.94%Color and Shape:Crystals From Methanol SolidMolecular weight:588.56Anti-p53 Antibody (9G324)
Anti-p53 Antibody (9G324) is an antibody targeting p53. Anti-p53 Antibody (9G324) can be used in ELISA, IF.Color and Shape:Odour LiquidAmifostine thiol dihydrochloride
CAS:Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.Formula:C5H16Cl2N2SPurity:100%Color and Shape:SolidMolecular weight:207.165BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.68%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.Formula:C29H23F3N4OPurity:99.24%Color and Shape:SolidMolecular weight:500.51LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formula:C36H42N6OPurity:99.56% - 99.93%Color and Shape:SolidMolecular weight:574.76Ref: TM-T6879
1mg44.00€2mg55.00€5mg85.00€10mg138.00€25mg304.00€50mg552.00€100mg787.00€1mL*10mM (DMSO)110.00€HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized Powder(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderLeptomycin B
CAS:Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.Formula:C33H48O6Purity:99.04% - 99.71%Color and Shape:White Crystalline SolidMolecular weight:540.73Ref: TM-T15735
1mg202.00€2mg341.00€5mg620.00€10mg882.00€25mg1,320.00€50mg1,776.00€100mg2,403.00€1mL*10mM (DMSO)283.00€SLMP53-1
CAS:SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37Ref: TM-T60839
1mg126.00€5mg298.00€10mg487.00€25mg938.00€50mg1,568.00€100mg2,517.00€1mL*10mM (DMSO)35.00€NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formula:C23H20N2OPurity:96.94%Color and Shape:SolidMolecular weight:340.42NSC 146109 hydrochloride
CAS:NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.Formula:C17H17ClN2SPurity:97.03%Color and Shape:SolidMolecular weight:316.85UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.25%Color and Shape:SolidMolecular weight:515.69O6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Formula:C12H11N5OPurity:98.90%Color and Shape:Solid CrystallineMolecular weight:241.25BMH-7 HCl
BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.Formula:C20H22ClN5OColor and Shape:SolidMolecular weight:383.88BAY 1892005
CAS:BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFormula:C11H8ClFN2OSPurity:99.62%Color and Shape:SoildMolecular weight:270.71BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderPifithrin-α, p-Nitro, Cyclic
CAS:Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.Formula:C15H13N3O2SPurity:99.43%Color and Shape:SolidMolecular weight:299.35Ref: TM-T12472
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg250.00€50mg406.00€100mg607.00€1mL*10mM (DMSO)87.00€Theaflavin 3,3'-digallate
CAS:Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFormula:C43H32O20Purity:98.71% - 99.86%Color and Shape:SolidMolecular weight:868.7BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02Ref: TM-T1959
1mg44.00€2mg55.00€5mg71.00€10mg107.00€25mg192.00€50mg274.00€100mg492.00€500mg1,103.00€1mL*10mM (DMSO)139.00€Anti-Phospho-TP53 (Ser9) Antibody (4M602)
Anti-Phospho-TP53 (Ser9) Antibody (4M602) is an antibody targeting Phospho-TP53 (Ser9). Anti-Phospho-TP53 (Ser9) Antibody (4M602) can be used in ELISA, IF.Color and Shape:Odour LiquidMethylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Formula:C28H31N3O6Purity:98.34% - 98.34%Color and Shape:SolidMolecular weight:505.56Anti-Phospho-TP53 (Ser33) Antibody (4K787)
Anti-Phospho-TP53 (Ser33) Antibody (4K787) is an antibody targeting Phospho-TP53 (Ser33). Anti-Phospho-TP53 (Ser33) Antibody (4K787) can be used in ELISA, IHC, IF.Color and Shape:Odour LiquidZMC1
CAS:NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Formula:C11H14N4SPurity:97.48% - 98.97%Color and Shape:SolidMolecular weight:234.32HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderHLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized Powder
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