Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Products of "Caspase"
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Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79%Color and Shape:SolidMolecular weight:428.44Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Formula:C9H18N2O3PtPurity:98.00%Color and Shape:SolidMolecular weight:397.33BOC-D-FMK
CAS:Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).Formula:C11H18FNO5Purity:98%Color and Shape:SolidMolecular weight:263.26Ref: TM-T10580
1mg51.00€5mg144.00€10mg210.00€25mg400.00€50mg603.00€100mg840.00€1mL*10mM (DMSO)139.00€CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purity:98.84%Color and Shape:SolidMolecular weight:411.41Ac-VRPR-AMC
CAS:Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].Formula:C34H51N11O7Purity:98%Color and Shape:SolidMolecular weight:725.84Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Formula:C29H32ClF3N2O3Purity:99.85%Color and Shape:SolidMolecular weight:549.02Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Formula:C15H12O3Purity:98.07%Color and Shape:SolidMolecular weight:240.25Caspase-3 activator 3
Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemicPurity:98%Color and Shape:Odour SolidM867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Formula:C27H43N7O6Purity:98%Color and Shape:SolidMolecular weight:561.67Diclofenac sodium
CAS:Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.Formula:C14H10Cl2NNaO2Purity:99.89% - 99.89%Color and Shape:White Or Off-White PowderMolecular weight:318.13MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purity:99.06%Color and Shape:SolidMolecular weight:441.95Caspase-3 activator 2
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,Purity:98%Color and Shape:Odour SolidTerfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67Ac-FLTD-CMK
CAS:Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.Formula:C26H37ClN4O8Purity:95.17%Color and Shape:SolidMolecular weight:569.05Ac-VRPR-AMC TFA
Ac-VRPR-AMC TFA serves as a fluorogenic substrate for metacaspases, enabling the assay of metacaspase activity.Formula:C38H53F6N11O11Color and Shape:SolidMolecular weight:953.88Diclofenac
CAS:Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.Formula:C14H11Cl2NO2Purity:99.78% - 99.97%Color and Shape:Crystals From Ether-Petroleum Ether SolidMolecular weight:296.15L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.1EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Formula:C47H76O18Purity:98% - 99.79%Color and Shape:SolidMolecular weight:929.1PQ401
CAS:PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).Formula:C18H16ClN3O2Purity:99.13%Color and Shape:SolidMolecular weight:341.79Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formula:C8H10O4Purity:98%Color and Shape:Needles From Petroleum Ether Slight Yellow PowderMolecular weight:170.16Brazilein
CAS:Brazilein, a natural antioxidant, inhibits adipocyte differentiation by inhibiting PPAR γ induction, inhibits skin cancer cells through increasing caspase-3 .Formula:C16H12O5Color and Shape:SolidMolecular weight:284.26Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formula:C26H46NNaO7SPurity:98.87%Color and Shape:SolidMolecular weight:539.70Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Formula:C27H44O7Purity:96.31% - 99.06%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Raptinal
CAS:Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.Formula:C28H18O2Purity:≥98%Color and Shape:SolidMolecular weight:386.44Ref: TM-T38563
1mg40.00€5mg88.00€10mg113.00€25mg180.00€50mg265.00€100mg393.00€200mg585.00€1mL*10mM (DMSO)87.00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formula:C23H28N4O2Purity:96.78% - 99.77%Color and Shape:SolidMolecular weight:392.49J22352
CAS:J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects inFormula:C24H21N3O4Color and Shape:SolidMolecular weight:415.44Caspase-3-IN-2
CAS:Caspase-3-IN-2 (Compound 4d) acts as an inhibitor of α-Chymotrypsin. It also exhibits inhibitory activity against HIV protease and caspase 3, with inhibition rates of 57% and 51% respectively at a concentration of 100 μM.Formula:C10H6ClNO5Color and Shape:SolidMolecular weight:255.6115,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purity:97.53%Color and Shape:SolidMolecular weight:312.32Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurity:98.12% - 99.93%Color and Shape:White SolidMolecular weight:499.7ZIF-8
CAS:ZIF-8 is an anticancer agent that can inherently trigger pyroptosis through a caspase-1/gasdermin D (GSDMD)-dependent pathway.Formula:C4H6N2ZnColor and Shape:SolidMolecular weight:147.5135,7-Dihydroxychromone
CAS:1.Formula:C9H6O4Purity:99.73% - ≥95%Color and Shape:SolidMolecular weight:178.14Ref: TM-T5S1805
1mg47.00€5mg88.00€10mg126.00€25mg208.00€50mg309.00€100mg462.00€500mg1,008.00€1mL*10mM (DMSO)80.00€Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.40% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg35.00€5mg55.00€10mg93.00€25mg178.00€50mg245.00€100mg360.00€200mg532.00€1mL*10mM (DMSO)60.00€Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:96.17% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Ref: TM-T6090
2mg37.00€5mg50.00€10mg86.00€25mg170.00€50mg235.00€100mg419.00€200mg617.00€1mL*10mM (DMSO)56.00€CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purity:98.19%Color and Shape:SolidMolecular weight:386.4Z-LEVD-FMK
CAS:Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.Formula:C31H45FN4O10Color and Shape:SolidMolecular weight:652.71Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Formula:C26H33NO6Purity:99.98%Color and Shape:White-To-Off-White Crystalline SolidMolecular weight:455.54Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Formula:C12H16O4Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:224.25Ref: TM-T5S2076
1mg48.00€5mg93.00€10mg123.00€25mg188.00€50mg283.00€100mg437.00€500mg938.00€1mL*10mM (DMSO)89.00€Sarglaroids F
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+Formula:C38H44O12Purity:98%Color and Shape:SolidMolecular weight:692.75Z-VAD(OMe)-FMK
CAS:View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.Formula:C22H30FN3O7Purity:95.92% - 99.44%Color and Shape:SolidMolecular weight:467.49Ref: TM-T6013
1mg57.00€2mg88.00€5mg144.00€10mg235.00€25mg349.00€50mg472.00€100mg658.00€200mg933.00€1mL*10mM (DMSO)145.00€KEA1-97
CAS:Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Formula:C15H9Cl2FN4Purity:98.7%Color and Shape:SolidMolecular weight:335.16Q-VD-OPH
CAS:Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.Formula:C26H25F2N3O6Purity:97.8% - 98.95%Color and Shape:SolidMolecular weight:513.5Licochalcone A
CAS:Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.Formula:C21H22O4Purity:98.11% - 98.96%Color and Shape:White Crystalline PowderMolecular weight:338.4Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purity:99.61% - ≥95%Color and Shape:White CrystalMolecular weight:307.43Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formula:C21H23FN2O4Purity:99.43% - 99.68%Color and Shape:SolidMolecular weight:386.42Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Formula:C22H34N4O13Purity:98.54%Color and Shape:SolidMolecular weight:562.52PHYTOSPHINGOSINE
CAS:Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.Formula:C18H39NO3Purity:99.53%Color and Shape:SolidMolecular weight:317.51Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFormula:C21H28FN3O7Purity:98.24% - 99.79%Color and Shape:SolidMolecular weight:453.46Ref: TM-T7020
1mg118.00€5mg245.00€10mg416.00€25mg662.00€50mg939.00€100mg1,264.00€200mg1,691.00€1mL*10mM (DMSO)269.00€
