IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Products of "IAP"
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Found 54 products on this category.
AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formula:C60H82N8O10Purity:97.76%Color and Shape:SolidMolecular weight:1075.36CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Color and Shape:Lyophilized PowderMolecular weight:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Color and Shape:Lyophilized PowderMolecular weight:48-65 KDa (reducing condition)Anti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Color and Shape:Odour LiquidCUDC-427
CAS:CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formula:C29H36N6O4SPurity:98.99%Color and Shape:SolidMolecular weight:564.7CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:40.7 kDa (predicted); 48-60 kDa (reducing condition, due to glycosylation)AZD5582
CAS:AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formula:C58H78N8O8Purity:98.75%Color and Shape:SolidMolecular weight:1015.29CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:17.1 kDa (predicted); 38.8 kDa (reducing conditions)GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurity:97.18% - 99.32%Color and Shape:SolidMolecular weight:498.64BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formula:C70H96N10O8Purity:97.46% - 99.89%Color and Shape:SolidMolecular weight:1205.57Ref: TM-T6428
1mg52.00€2mg67.00€5mg95.00€10mg153.00€25mg301.00€50mg567.00€100mg810.00€1mL*10mM (DMSO)188.00€ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purity:97.81% - 98.33%Color and Shape:SolidMolecular weight:539.68Ref: TM-TQ0029
1mg84.00€5mg144.00€10mg216.00€25mg432.00€50mg638.00€100mg908.00€1mL*10mM (DMSO)172.00€CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Color and Shape:Lyophilized PowderMolecular weight:13.8 kDa (predicted)Anti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Color and Shape:Odour LiquidSM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formula:C62H84N14O6Purity:97.25% - 99.92%Color and Shape:SolidMolecular weight:1121.42Anticancer agent 128
CAS:Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formula:C26H38N4O4Purity:98%Color and Shape:SolidMolecular weight:470.6LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurity:99.13% - 99.72%Color and Shape:SolidMolecular weight:500.63SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Formula:C62H85ClN14O6Purity:98%Color and Shape:SolidMolecular weight:1157.88Anti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Color and Shape:Odour LiquidXevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formula:C32H43N5O4Purity:98% - 99.48%Color and Shape:SolidMolecular weight:561.71Ref: TM-T6763
1mg43.00€2mg57.00€5mg93.00€10mg131.00€25mg279.00€50mg525.00€100mg745.00€200mg1,008.00€500mg1,320.00€1mL*10mM (DMSO)145.00€Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purity:99.77% - ≥98%Color and Shape:SolidMolecular weight:1209.4CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:40.6 kDa (predicted)Anti-CD47 Antibody (4E249)
Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (5E321)
Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Color and Shape:Odour LiquidAlkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and isPurity:92.7%Color and Shape:Lyophilized PowderMolecular weight:54.1 kDa (predicted); 66 kDa (reducing conditions)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Color and Shape:Lyophilized PowderMolecular weight:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Purity:SDS-PAGE: 100%; SEC-HPLC: 97% - SDS-PAGE: 100%; SEC-HPLC: 97%Color and Shape:Lyophilized PowderMolecular weight:30-45 KDa (reducing condition)Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColor and Shape:Lyophilized PowderMolecular weight:53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.Alkaline phosphatase Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.4%Color and Shape:Lyophilized PowderMolecular weight:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.Purity:97.6%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted)N-Deshydroxyethyl Dasatinib
CAS:N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAPFormula:C20H22ClN7OSPurity:95.96%Color and Shape:SolidMolecular weight:443.95Ref: TM-T18750
1mg92.00€5mg188.00€10mg298.00€25mg515.00€50mg750.00€100mg1,026.00€500mg2,072.00€1mL*10mM (DMSO)215.00€Anti-CD47 Antibody (1F304)
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.Color and Shape:Odour LiquidAlkaline phosphatase Protein, Human, Recombinant (hFc)
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Color and Shape:Lyophilized PowderMolecular weight:15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Color and Shape:Lyophilized PowderMolecular weight:60-90 KDa (reducing condition)Anti-CD47 Antibody-FITC (9X161)
Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.Color and Shape:Odour LiquidCD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Color and Shape:Lyophilized PowderMolecular weight:39.9 kDa (predicted)CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Color and Shape:Lyophilized PowderMolecular weight:33-55 KDa (reducing condition)Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColor and Shape:Lyophilized PowderMolecular weight:54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.Anti-CD47 Antibody (5K435)
Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidCD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.Color and Shape:Lyophilized PowderMolecular weight:30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (aa 19-139, His)
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:15.17kDa (predicted); 34.13 kDa (reducing conditions)MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formula:C27H26N2O4SPurity:97.27% - 99.57%Color and Shape:SolidMolecular weight:474.57Ref: TM-T3653
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg227.00€50mg368.00€100mg547.00€500mg1,198.00€1mL*10mM (DMSO)82.00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Anti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Color and Shape:Odour LiquidMV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Formula:C33H44N4O5Purity:97.96%Color and Shape:SolidMolecular weight:576.73Ref: TM-T16163
1mg46.00€5mg92.00€10mg170.00€25mg283.00€50mg424.00€100mg598.00€200mg785.00€1mL*10mM (DMSO)117.00€Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormula:C42H56F2N8O6Purity:97.08% - ≥95%Color and Shape:SolidMolecular weight:806.94CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:60-70 KDa (reducing condition)Anti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Color and Shape:Odour LiquidCD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Purity:97.8%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Formula:C26H37FN4O6SPurity:98%Color and Shape:SolidMolecular weight:552.66Anti-CD47 Antibody (8K78)
Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidIsolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purity:99.62%Color and Shape:SolidMolecular weight:244.29Ref: TM-T8213
1mg78.00€5mg169.00€10mg271.00€25mg459.00€50mg658.00€100mg914.00€200mg1,225.00€1mL*10mM (DMSO)157.00€
