Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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LY3143921 hydrate
CAS:LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].Formula:C16H14FN5O2Purity:98.43%Color and Shape:SolidMolecular weight:327.31CDK2-IN-39
CAS:CDK2-IN-39 (compound 4) is a CDK2 inhibitor.Formula:C14H15N3O4SColor and Shape:SolidMolecular weight:321.352COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Formula:C22H16N2O5SPurity:97.04% - 98.92%Color and Shape:SolidMolecular weight:420.44Ref: TM-T3157
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg217.00€50mg354.00€100mg590.00€1mL*10mM (DMSO)87.00€5'-Azido-5'-deoxythymidine
CAS:5'-Azido-5'-deoxythymidine is a nucleoside analog with potential anti-tuberculosis activity and an inhibitor of TMPKmt in Mycobacterium tuberculosis.Formula:C10H13N5O4Purity:99.85%Color and Shape:SolidMolecular weight:267.24NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Formula:C13H16NNaO4SPurity:99.64%Color and Shape:SolidMolecular weight:305.32Ref: TM-T3589
1mg47.00€2mg59.00€5mg93.00€10mg115.00€25mg245.00€50mg437.00€100mg625.00€1mL*10mM (DMSO)93.00€CCT241533
CAS:CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Formula:C23H27FN4O4Purity:98%Color and Shape:SolidMolecular weight:442.48BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
CAS:BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (Formula:C41H45Cl3N4O5Purity:98%Color and Shape:SoildMolecular weight:780.18TASIN-1 Hydrochloride
CAS:TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncatedFormula:C18H29ClN2O3SPurity:99.84%Color and Shape:SolidMolecular weight:388.95Ref: TM-T24855
1mg78.00€5mg143.00€10mg197.00€25mg335.00€50mg477.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)150.00€Abemaciclib methanesulfonate
CAS:Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).Formula:C27H32F2N8·CH4O3SPurity:98.69% - 99.44%Color and Shape:SolidMolecular weight:602.7CDK12/13-IN-2
CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.Formula:C24H22FN7O2Color and Shape:SolidMolecular weight:459.48WRN inhibitor 12
CAS:WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.Formula:C33H33ClF3N9O5Color and Shape:SolidMolecular weight:728.12Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68WAY-322243
CAS:WAY-322243 has antibacterial and anti-inflammatory activity and has an inhibitory effect on CLK-1, which can be used to study Alzheimer's disease.Formula:C18H18N2O2SPurity:99.47%Color and Shape:SoildMolecular weight:326.41TP-353
CAS:TP-353 (EOS-61973) is a CDK7 inhibitor.Formula:C35H30FNO3Purity:99.12%Color and Shape:SolidMolecular weight:531.62Ref: TM-T22440
1mg59.00€2mg80.00€5mg108.00€10mg187.00€25mg341.00€50mg472.00€100mg652.00€200mg899.00€1mL*10mM (DMSO)158.00€CDK12/13 ligand 1
CAS:ALK-IN-29 (compound 4c) exhibits notable inhibitory activity against tyrosine kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, showing a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is useful for cancer research.Formula:C26H26BrN5OColor and Shape:SolidMolecular weight:504.42D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formula:C23H36N6SPurity:99.04%Color and Shape:SolidMolecular weight:428.64Ref: TM-T10936
1mg37.00€2mg52.00€5mg77.00€10mg126.00€25mg283.00€50mg390.00€100mg567.00€1mL*10mM (DMSO)85.00€NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.76Ref: TM-T9093
1mg87.00€5mg187.00€10mg298.00€25mg525.00€50mg747.00€100mg1,017.00€1mL*10mM (DMSO)264.00€WEE1-IN-11
CAS:WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.Formula:C26H29FN8OS2Color and Shape:SolidMolecular weight:552.69Blinatumomab
CAS:Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.Color and Shape:LiquidAPE1-IN-1
CAS:APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cellsFormula:C19H21N3OS2Purity:98.50%Color and Shape:SolidMolecular weight:371.52Plogosertib
CAS:Plogosertib (CYC140) is a PLK1 inhibitor with an IC50 value of 3 nM.Plogosertib is antiproliferative and can be used to study solid and hematologic tumors.Formula:C34H48N8O3Purity:99.15% - 99.85%Color and Shape:SolidMolecular weight:616.797P18IN003
CAS:P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion ofFormula:C17H16N2O3Purity:98.77%Color and Shape:SolidMolecular weight:296.32AM5992
CAS:AM5992 (example 195) is a potent CDK4 and CDK6 inhibitor (CDK4, IC50= 0.013 μM). AM5992 can be used for the research of CDK4-mediated disorders.Formula:C27H33FN8OPurity:98%Color and Shape:SoildMolecular weight:504.6Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurity:100% - 99.70%Color and Shape:SolidMolecular weight:595.71P18IN011
CAS:P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).Formula:C15H12N2O5SPurity:97.63%Color and Shape:SolidMolecular weight:332.33Ref: TM-T8576
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)178.00€Ethynylcytidine
CAS:Ethynylcytidine is a nucleoside antimetabolite.Formula:C11H13N3O5Purity:98%Color and Shape:SolidMolecular weight:267.24TMX-3013
CAS:TMX-3013 is a CDK inhibitor that targets multiple cyclin-dependent kinases, specifically suppressing the activity of CDK1, CDK2, CDK4, CDK5, and CDK6 with IC50 values of 0.9 nM, <0.5 nM, 24.5 nM, 0.5 nM, and 15.6 nM respectively. Additionally, TMX-3013 is utilized in the synthesis of PROTACs, which use polyethylene glycol (PEG) as a linker and Thalidomide as the CRBN-recruiting arm.Formula:C17H14BrFN6O3SColor and Shape:SolidMolecular weight:481.3UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formula:C17H17N3SPurity:99.81%Color and Shape:SolidMolecular weight:295.4PD-1/PD-L1-IN-32
PD-1/PD-L1-IN-32 (compound A56) is a potent inhibitor of PD-1/PD-L1, displaying pronounced anticancer activity with an IC50 value of 2.4 nM.Purity:98%Color and Shape:Odour SolidTMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formula:C72H66N8O12S4Purity:99.11% - 99.85%Color and Shape:SolidMolecular weight:1363.6GSK4418959
CAS:GSK4418959 (IDE275) is an oral, non-covalent, reversible, and selective WRN helicase inhibitor.inhibits ATPase and DNA unwinding functions. MSI-H.Formula:C31H30F4N4O5SColor and Shape:SoildMolecular weight:646.65AVG-233
CAS:AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.Formula:C26H22ClN5O3Purity:99%Color and Shape:SolidMolecular weight:487.94GW8510
CAS:GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Formula:C21H15N5O3S2Purity:99.32%Color and Shape:SolidMolecular weight:449.51Ref: TM-T24125
1mg52.00€5mg97.00€10mg169.00€25mg329.00€50mg537.00€100mg868.00€200mg1,169.00€1mL*10mM (DMSO)111.00€IMMH 010 maleate
CAS:IMMH 010 maleate (YPD-30 maleate) is a programmed cell death ligand 1 inhibitor used in the study of neurological disorders and advanced malignant solid tumors.Formula:C36H36BrClN2O9Color and Shape:SoildMolecular weight:756.04NCGC00029283
CAS:NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μMFormula:C18H12FN3O3Purity:99.6%Color and Shape:SolidMolecular weight:337.3Ref: TM-T40823
1mg111.00€2mg163.00€5mg264.00€10mg432.00€25mg747.00€50mg1,103.00€100mg1,539.00€1mL*10mM (DMSO)283.00€Docosanoic acid
CAS:Docosanoic acid (Behenic Acid) is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.Formula:C22H44O2Purity:100%Color and Shape:Waxy Solid Liquid Othersolid PelletslargecrystalsMolecular weight:340.58N6-Methyladenine
CAS:N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.Formula:C6H7N5Purity:98.35%Color and Shape:SolidMolecular weight:149.15Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formula:C32H38O19Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:726.63Poloxin-2
CAS:Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.Formula:C16H15NO3Purity:99.59%Color and Shape:SolidMolecular weight:269.3Ref: TM-T25969
1mg333.00€5mg922.00€10mg1,140.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,664.00€2′-C-Methyl-6-O-methylinosine
CAS:6-MeO-9-(2-C-methyl-β-D-ribofuranosyl)purine is a hypoxanthine analog used in tumor disease research.Formula:C12H16N4O5Purity:99.09%Color and Shape:SolidMolecular weight:296.28Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Color and Shape:LiquidXPW1
CAS:XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.Formula:C36H39ClFN7O2Purity:98.08%Color and Shape:SoildMolecular weight:656.19Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formula:C12H11N5OPurity:99.27% - 99.95%Color and Shape:SolidMolecular weight:241.25Ref: TM-T12399
1mg114.00€5mg274.00€10mg439.00€25mg727.00€50mg1,017.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)303.00€Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg43.00€5mg66.00€10mg94.00€25mg159.00€50mg230.00€100mg346.00€200mg520.00€1mL*10mM (DMSO)74.00€c-Myc inhibitor 12
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].Formula:C22H24N6OPurity:98%Color and Shape:SolidMolecular weight:388.478-Azaguanine
CAS:8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.Formula:C4H4N6OPurity:100% - 99.89%Color and Shape:White To Off-White Crystalline PowderMolecular weight:152.11Clofarabine-5'-diphosphate
CAS:Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Formula:C10H13ClFN5O9P2Color and Shape:SolidMolecular weight:463.64MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg56.00€5mg131.00€10mg187.00€25mg319.00€50mg449.00€100mg638.00€200mg842.00€1mL*10mM (DMSO)143.00€2'-Deoxycytidine hydrochloride
CAS:2'-Deoxycytidine hydrochloride is an important deoxyribonucleoside analog and protects mice from the lethal toxicity of cytosine arabinoside(araC).Formula:C9H14ClN3O4Purity:98.96%Color and Shape:White To Off-White Crystalline PowderMolecular weight:263.68GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.21Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46Ref: TM-T37113
1mg38.00€5mg80.00€10mg111.00€25mg183.00€50mg269.00€100mg393.00€200mg560.00€1mL*10mM (DMSO)92.00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.82%Color and Shape:SolidMolecular weight:249.35Ezabenlimab
CAS:Ezabenlimab (BI-754091) is an anti-PD-1 mAb, Kd 6 nM, blocks PD-1/PD-Ls, boosts T-cell IFN-γ, inhibits tumors in vivo.Purity:95% - 95%Color and Shape:LiquidLY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39Ref: TM-T4061
1mg62.00€5mg131.00€10mg205.00€25mg378.00€50mg562.00€100mg777.00€200mg1,074.00€1mL*10mM (DMSO)166.00€PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purity:98%Color and Shape:SolidMolecular weight:554.08BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
1mg37.00€2mg52.00€5mg79.00€10mg126.00€25mg274.00€50mg454.00€100mg655.00€1mL*10mM (DMSO)87.00€CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formula:C26H25F3N8OPurity:99.49%Color and Shape:SolidMolecular weight:522.52TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Formula:C19H29ClN6OPurity:98%Color and Shape:SolidMolecular weight:392.93Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purity:100% - 99.82%Color and Shape:SolidMolecular weight:518.92Ref: TM-T2241
5mg55.00€10mg96.00€25mg155.00€50mg226.00€100mg354.00€200mg454.00€500mg743.00€1mL*10mM (DMSO)63.00€4μ8C
CAS:4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.Formula:C11H8O4Purity:97.48% - 98.45%Color and Shape:SolidMolecular weight:204.18CDK-IN-15
CAS:CDK-IN-15 (Compound 456) is an effective inhibitor of Cyclin A, exhibiting an IC50 value of 0.14 μM.Formula:C45H63Cl2F4N7O8Color and Shape:SolidMolecular weight:976.92GDC0575 monohydrochloride
CAS:GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.Formula:C16H21BrClN5OPurity:97.85%Color and Shape:SolidMolecular weight:414.73Ref: TM-T27407
1mg46.00€2mg58.00€5mg85.00€10mg108.00€25mg187.00€50mg269.00€100mg376.00€200mg548.00€1mL*10mM (DMSO)87.00€CDK9-IN-2
CAS:CDK9-IN-2, a CDK9 inhibitor from patent WO/2012131594A1, IC50: 5 nM in A2058, 7 nM in H929 at 72hr.Formula:C23H25ClFN5Purity:99%Color and Shape:SolidMolecular weight:425.93Ref: TM-T14918
1mg88.00€5mg187.00€10mg281.00€25mg487.00€50mg705.00€100mg998.00€1mL*10mM (DMSO)207.00€Emzadirib
CAS:Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.Formula:C27H40N4O6S2Purity:99.79%Color and Shape:SolidMolecular weight:580.7610074-A4
CAS:10074-A4 is a c-Myc binding compound that associates with c-Myc370-409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features fromFormula:C18H14Cl2N2O3SPurity:98.01%Color and Shape:SolidMolecular weight:409.29Ref: TM-T9628
1mg71.00€5mg135.00€10mg197.00€25mg335.00€50mg480.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)156.00€BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.58%Color and Shape:SolidMolecular weight:561.3AG-024322
CAS:AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.Formula:C23H20F2N6Purity:98.53%Color and Shape:SolidMolecular weight:418.44TG003
CAS:TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.Formula:C13H15NO2SPurity:99.46%Color and Shape:SolidMolecular weight:249.33Ref: TM-T60367
1mg50.00€5mg97.00€10mg159.00€25mg281.00€50mg465.00€100mg558.00€200mg810.00€1mL*10mM (DMSO)170.00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purity:98.20%Color and Shape:SolidMolecular weight:501.62T4 UvsX Recombinase
T4 UvsX Recombinase initiates DNA replication on double-stranded templates by catalyzing synapsis with a homologous primer single strand.Purity:98%Color and Shape:Odour SoliddGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purity:99.9%Color and Shape:SolidMolecular weight:507.18Avotaciclib hydrochloride
Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, includingFormula:C13H12ClN7OPurity:98%Color and Shape:SolidMolecular weight:317.73RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purity:98.85% - 99.86%Color and Shape:SolidMolecular weight:433.28Ref: TM-T2628
1mg73.00€2mg97.00€5mg160.00€10mg281.00€25mg435.00€50mg640.00€100mg910.00€1mL*10mM (DMSO)170.00€CDK9-IN-29
CAS:CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.Formula:C29H33F2N5O4Purity:98%Color and Shape:SolidMolecular weight:553.6PD-1/PD-L1-IN-50
Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.Color and Shape:Odour SolidBMS-8
CAS:BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.Formula:C27H28BrNO3Purity:99.06%Color and Shape:SolidMolecular weight:494.42Ref: TM-T26859
1mg39.00€5mg84.00€10mg131.00€25mg269.00€50mg432.00€100mg638.00€200mg909.00€1mL*10mM (DMSO)96.00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurity:98% - 99.75%Color and Shape:SolidMolecular weight:393.49Ref: TM-T1825
1mg38.00€2mg49.00€5mg70.00€10mg88.00€25mg164.00€50mg224.00€100mg393.00€1mL*10mM (DMSO)70.00€10074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:97.22% - 99.67%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg42.00€5mg63.00€10mg88.00€25mg142.00€50mg225.00€100mg396.00€200mg565.00€500mg900.00€1mL*10mM (DMSO)69.00€9-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formula:C17H22N6OPurity:100%Color and Shape:SolidMolecular weight:326.4Ref: TM-T23589
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)642.00€PD-1/PD-L1-IN-27
CAS:PD-1/PD-L1-IN-27: potent anti-cancer, IC50 134nM, minimal T cell harm, boosts CD8+ T cells, reduces fatigue.Formula:C44H35NO6Purity:98%Color and Shape:SolidMolecular weight:673.75Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.21%Color and Shape:SolidMolecular weight:447.48CAN508
CAS:CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Formula:C9H10N6OPurity:98.65%Color and Shape:SolidMolecular weight:218.22H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:100%Color and Shape:SolidMolecular weight:614.61CDK9 ligand 3
CAS:CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.Formula:C18H18BrCl2N5O3Color and Shape:SolidMolecular weight:503.177MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Formula:C24H25F3N6SPurity:97.17% - 98%Color and Shape:SolidMolecular weight:486.56Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86Ref: TM-T12609
1mg75.00€5mg170.00€10mg256.00€25mg423.00€50mg562.00€100mg792.00€200mg1,074.00€1mL*10mM (DMSO)182.00€PD-1/PD-L1-IN-52
PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally active inhibitor of PD-1/PD-L1 interaction, exhibiting an IC50 of 109.9 nM. It demonstrates antitumor activity in a C57BL/6 mouse model of MC38 colon carcinoma cells expressing human PD-1, achieving a tumor growth inhibition (TGI) rate of 49.6%.Color and Shape:Odour SolidAKI603
CAS:AKI603: Aurora A kinase blocker; IC50 12.3 nM; targets BCR-ABL-T315I resistance; halts leukemia cell growth.Formula:C19H23N9O2Purity:99.81%Color and Shape:SolidMolecular weight:409.45Ref: TM-T64338
1mg66.00€5mg145.00€10mg212.00€25mg380.00€50mg562.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)160.00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2DNA Gyrase-IN-13
CAS:DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.Formula:C15H21N3O3SColor and Shape:SolidMolecular weight:323.41Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67Ref: TM-T16703
1mg119.00€5mg169.00€10mg264.00€25mg487.00€50mg652.00€100mg847.00€1mL*10mM (DMSO)234.00€LY3295668
CAS:LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.Formula:C24H26ClF2N5O2Purity:99.44%Color and Shape:SolidMolecular weight:489.95iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg56.00€2mg78.00€5mg99.00€10mg149.00€25mg258.00€50mg393.00€100mg582.00€1mL*10mM (DMSO)110.00€Sasanlimab
CAS:Sasanlimab (PF-06801591), a humanized IgG4-κ antibody, selectively targets PD-1 and is primarily produced in Chinese Hamster Ovary (CHO) cells [1].Purity:98%Color and Shape:Liquid(2S,3R)-Voruciclib
CAS:(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.Formula:C22H19ClF3NO5Purity:98%Color and Shape:SolidMolecular weight:469.84CDK1-IN-6
CDK1-IN-6 (Ligand 3) is an effective inhibitor of CDK1 and shows potential for use in cancer research.Formula:C21H22N4OColor and Shape:SolidMolecular weight:346.43Gallium maltolate
CAS:Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.Formula:C18H15GaO9Purity:99.67% - 99.75%Color and Shape:SolidMolecular weight:445.03Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71TMX-2039
CAS:TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.Formula:C17H20BrFN6O3SColor and Shape:SolidMolecular weight:487.347Stigmatellin
CAS:Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.Formula:C30H42O7Color and Shape:SolidMolecular weight:514.65MGB-BP-3
CAS:MGB-BP-3 is a synthetic antibiotic with bactericidal activity that inhibits bacterial DNA replication and can be used to study recurrent C. difficile infections.Formula:C36H37N7O4Purity:97.06% - 98.92%Color and Shape:SolidMolecular weight:631.72STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Purity:95% - 95%Color and Shape:Odour Liquid2',3'-Dideoxyuridine
CAS:2',3'-Dideoxyuridine is a purine nucleoside analog with potential antitumor activity.Formula:C9H12N2O4Purity:99.76%Color and Shape:SolidMolecular weight:212.2WRN inhibitor 11
CAS:WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.Formula:C34H35ClF3N9O5Color and Shape:SolidMolecular weight:742.15C16Y
CAS:C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.Formula:C78H115N17O17Color and Shape:SolidMolecular weight:1562.85EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.535-Methylcytosine
CAS:5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.Formula:C5H7N3OPurity:99.17%Color and Shape:SolidMolecular weight:125.13SRI-29329
CAS:SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Formula:C20H26ClN7Purity:99.18%Color and Shape:SolidMolecular weight:399.92Ref: TM-T8801
1mg92.00€5mg188.00€10mg306.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)215.00€3-AP
CAS:3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).Formula:C7H9N5SPurity:97.33% - 99.75%Color and Shape:SolidMolecular weight:195.24Ref: TM-T1982
2mg39.00€5mg57.00€10mg69.00€25mg150.00€50mg264.00€100mg400.00€500mg909.00€1mL*10mM (DMSO)57.00€Human PD-L1 inhibitor V
CAS:Human PD-L1 Inhibitor V is a peptide that binds to the human PD-1 protein with an affinity characterized by a dissociation constant (Kd) of 3.32 μM, effectivelyFormula:C65H104N20O18SPurity:98%Color and Shape:SolidMolecular weight:1485.71T521
CAS:T521 is a selective inhibitor of the PBD of Plk1 and shows no inhibitory effect on Plk2 and Plk3.Formula:C17H14FNO5S2Purity:99.65%Color and Shape:SolidMolecular weight:395.43AZ5576
CAS:AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].Formula:C21H24FN3O3Purity:99.88%Color and Shape:SoildMolecular weight:385.43Ref: TM-T60152
1mg35.00€5mg80.00€10mg113.00€25mg221.00€50mg331.00€100mg475.00€500mg938.00€1mL*10mM (DMSO)87.00€PROTAC CDK9 degrader-11
CAS:PROTAC CDK9 degrader-11 (Compound C3) is an orally active PROTAC CDK9 degrader with a DC50 of 1.09 nM. This compound exhibits cytotoxicity in small cell lung cancer (SCLC) cells, with IC50 values in the nanomolar range. It induces cell cycle arrest at the G0/G1 phase and inhibits cell invasion in DMS114 and DMS53 cells. In addition, PROTAC CDK9 degrader-11 shows antitumor activity in an NCI-H446 xenograft mouse model. (Pink: ligand for target protein CDK9 ligand 3; Black: linker; Blue: ligand for E3 ligase Cereblon E3 ligase Ligand 56)Formula:C39H48Cl2N10O5Color and Shape:SolidMolecular weight:807.768SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purity:99.95%Color and Shape:SolidMolecular weight:376.25Ref: TM-T3700
1mg49.00€2mg70.00€5mg96.00€10mg155.00€25mg264.00€50mg424.00€100mg627.00€1mL*10mM (DMSO)114.00€Senexin C
CAS:Senexin C is a CDK8/19 inhibitor with anticancer activity.Senexin C inhibits the growth of MV4-11 leukemia cells.Formula:C28H27N5OPurity:97.91%Color and Shape:SolidMolecular weight:449.55DAM-IN-1
CAS:DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.Formula:C16H17NO4Purity:98%Color and Shape:SolidMolecular weight:287.31Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Formula:C19H26ClN7OPurity:99.64%Color and Shape:SolidMolecular weight:403.91Ref: TM-T22260
2mg42.00€5mg64.00€10mg97.00€25mg183.00€50mg284.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)65.00€Sintilimab
CAS:Sintilimab (IBI308), an IgG4 monoclonal antibody, blocks PD-1, enhancing T-cell anti-tumor response; treats Hodgkin's, lung, and esophageal cancers.Purity:> 95%Color and Shape:LiquidMolecular weight:144.04 kDaAtuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43PD-1-IN-22
CAS:PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).Formula:C25H25N5O4Purity:98.64%Color and Shape:SolidMolecular weight:459.5Ref: TM-T12379
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)299.00€CFI-402257
CAS:CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.Formula:C28H30N6O3Purity:96.66% - 99.51%Color and Shape:SolidMolecular weight:498.58CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBCPurity:98%Color and Shape:Odour SolidDamnacanthal
CAS:Damnacanthal is a natural anthraquinone with potential anticancer property, inhibiting a variety of protein kinases such as LIMK1, LIMK2 and Lck.Formula:C16H10O5Purity:98%Color and Shape:SolidMolecular weight:282.25RNA polymerase II-IN-1
CAS:RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.Formula:C38H53N11O12SPurity:98%Color and Shape:SolidMolecular weight:887.96SAR-020106
CAS:SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.Formula:C19H19ClN6OPurity:97.78%Color and Shape:SolidMolecular weight:382.85CDK4-IN-1
CAS:CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50Formula:C22H29ClN8Purity:98%Color and Shape:SolidMolecular weight:440.97Aurora A inhibitor 3
Aurora A Inhibitor 3 (Compound 5h) effectively inhibits Aurora-A kinase, exhibiting an IC50 of 0.78 μM, and demonstrates cytotoxicity against MCF-7 and MDA-MB-Purity:98%Color and Shape:Odour SolidProguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurity:98.43% - 99.89%Color and Shape:SolidMolecular weight:332.45-Aza-7-deazaguanine
CAS:5-Aza-7-deazaguanine is a non-natural substituted nucleobase with potential antiviral activity, used in cancer and bacterial infection research.Formula:C5H5N5OPurity:98.87%Color and Shape:SolidMolecular weight:151.138-Azaguanosine
CAS:8-Azaguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity and is used in the study of a variety of tumor diseases.Formula:C9H12N6O5Purity:99.44%Color and Shape:SolidMolecular weight:284.23BI8622
CAS:BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.Formula:C25H26N6OPurity:98.28%Color and Shape:SolidMolecular weight:426.51(S)-Enitociclib
CAS:(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Formula:C19H18F2N4O2SPurity:98.04%Color and Shape:SolidMolecular weight:404.43Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purity:99.61% - 99.9%Color and Shape:SolidMolecular weight:138.12AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:100%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg131.00€2mg180.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)303.00€CDK8/19-IN-51
CAS:CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formula:C23H22N6O2Purity:100% - 98.65%Color and Shape:SoildMolecular weight:414.46KOdiA-PC
CAS:KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.Formula:C32H58NO11PColor and Shape:SolidMolecular weight:663.78Envafolimab
CAS:Envafolimab (ASC 22) is a humanized antibody targeting PD-L1, with anticancer activity, blocking the PD-L1 and PD-1 interaction.Purity:95%Color and Shape:LiquidLY2880070
CAS:LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.Formula:C19H23N7O2Purity:99.77%Color and Shape:SolidMolecular weight:381.43Ref: TM-T9252
1mg131.00€5mg286.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€1mL*10mM (DMSO)316.00€WAY-647802
CAS:WAY-647802 is a CDK inhibitor.Formula:C11H14N4O3Purity:98.38%Color and Shape:SolidMolecular weight:250.25Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formula:C16H17N5O2Purity:99.44% - 99.61%Color and Shape:SolidMolecular weight:311.34PD-1/PD-L1-IN-51
PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.Color and Shape:Odour SolidCCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formula:C26H31BrN8OPurity:98.51% - 99.82%Color and Shape:SolidMolecular weight:551.485'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formula:C38H37N3O7Purity:98.88%Color and Shape:SolidMolecular weight:647.72Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaSR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Formula:C26H32O2Purity:98%Color and Shape:SolidMolecular weight:376.53Ref: TM-T23384
1mg137.00€5mg492.00€10mg797.00€25mg1,385.00€50mgTo inquire100mgTo inquire1mL*10mM (DMSO)550.00€Nedaplatin
CAS:Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.Formula:C2H8N2O3PtPurity:100% - 98.69%Color and Shape:Straw Yellow PowderMolecular weight:303.17A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Ref: TM-T2254
2mg44.00€5mg52.00€10mg81.00€25mg160.00€50mg271.00€100mg532.00€500mg1,169.00€1mL*10mM (DMSO)71.00€N-6-Furfurylguanosine
CAS:N-6-Furfurylguanosine (kinetin riboside) is a purine nucleoside analog with cytotoxicity, inhibiting the growth of cancer cells.Formula:C15H18N6O5Purity:99.58%Color and Shape:SolidMolecular weight:362.34Ancitabine hydrochloride
CAS:Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.Formula:C9H12ClN3O4Purity:99.02% - 99.37%Color and Shape:White SolidMolecular weight:261.66Uridine-5-acetic acid
CAS:Uridine-5-acetic acid (5-Carboxymethyluridine) is a nucleoside formed during RNA transfer processes in yeast and wheat embryos.Formula:C11H14N2O8Purity:99.59%Color and Shape:SolidMolecular weight:302.24PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.9Ref: TM-T84770
1mg92.00€5mg188.00€10mg313.00€25mg603.00€50mg840.00€100mg1,169.00€200mg1,586.00€1mL*10mM (DMSO)216.00€CHK1 inhibitor
CAS:CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formula:C17H21BrN4OPurity:98%Color and Shape:SolidMolecular weight:377.28Saccharin 1-methylimidazole
CAS:Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.Formula:C7H5NO3S·C4H6N2Purity:98.21%Color and Shape:SolidMolecular weight:265.29THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purity:95.09% - 99.27%Color and Shape:SolidMolecular weight:566.05Antiviral agent 36
Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100Formula:C30H32N4O3Purity:98%Color and Shape:SolidMolecular weight:496.6m-Se3
CAS:m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].Formula:C29H23IN2SePurity:98%Color and Shape:SolidMolecular weight:605.37CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Formula:C23H18N6O2SPurity:97.24% - 99.10%Color and Shape:SolidMolecular weight:442.49Ref: TM-T14916
1mg87.00€5mg202.00€10mg321.00€25mg550.00€50mg753.00€100mg1,074.00€1mL*10mM (DMSO)240.00€Bersiporocin
CAS:Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.Formula:C15H19Cl2N3OPurity:100% - 98.88%Color and Shape:SolidMolecular weight:328.24ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44Ref: TM-T16391
1mg50.00€5mg74.00€10mg105.00€25mg182.00€50mg283.00€100mg425.00€200mg602.00€1mL*10mM (DMSO)64.00€ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurity:99.34%Color and Shape:SolidMolecular weight:363.23Ref: TM-T13147
1mg185.00€5mg393.00€10mg587.00€25mg935.00€50mg1,264.00€100mg1,700.00€500mg3,410.00€1mL*10mM (DMSO)432.00€CDK2-IN-40
CAS:CDK9-IN-40 is an inhibitor of CDK2 (Cyclin-dependent kinase 2). It effectively inhibits CDK2/Cyclin E1, with an IC50 of ≤ 10 nM.Formula:C16H21N7O2Color and Shape:SolidMolecular weight:343.384MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formula:C26H16ClF9N2O2Purity:99.52%Color and Shape:SolidMolecular weight:594.86Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurity:98.07%Color and Shape:SolidMolecular weight:302.39Ref: TM-T3118
1mg35.00€2mg48.00€5mg62.00€10mg87.00€25mg156.00€50mg235.00€100mg354.00€1mL*10mM (DMSO)67.00€Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Formula:C27H36N8O5Purity:99.90%Color and Shape:SolidMolecular weight:552.63Ref: TM-T15732
2mg35.00€5mg51.00€10mg73.00€25mg97.00€50mg115.00€100mg168.00€200mg271.00€500mg484.00€1mL*10mM (DMSO)64.00€HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.68%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€WRN inhibitor 14
WRN inhibitor 14 (compound S35) is an orally administered WRN inhibitor with anticancer properties. It effectively suppresses tumor growth in the SW48 xenograft model in BALB/c nude mice.Formula:C35H40F4N10O5Color and Shape:SolidMolecular weight:756.75Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Formula:C46H52Na2O16Purity:98%Color and Shape:SolidMolecular weight:906.888-Bromoadenosine
CAS:8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.Formula:C10H12BrN5O4Purity:99.11%Color and Shape:SolidMolecular weight:346.14SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formula:C15H18Br2N4Purity:100% - 99.7%Color and Shape:SolidMolecular weight:414.14NSAH
CAS:NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-Formula:C18H14N2O3Purity:99.27%Color and Shape:SolidMolecular weight:306.32Ref: TM-T8800
5mg70.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)77.00€CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formula:C11H8F3N3OPurity:97.09%Color and Shape:SolidMolecular weight:255.2Ref: TM-T10740
1mg87.00€5mg216.00€10mg311.00€25mg525.00€50mg707.00€100mg944.00€1mL*10mM (DMSO)240.00€Rifalazil
CAS:Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.Formula:C51H64N4O13Purity:98%Color and Shape:SolidMolecular weight:941.07GTSE1-IN-1
CAS:GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.Formula:C21H24FN7Color and Shape:SolidMolecular weight:393.46Rifapentine
CAS:Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.Formula:C47H64N4O12Purity:95.74% - ≥98%Color and Shape:SolidMolecular weight:877.032-Methylbiphenyl-oxadiazole-NH-Ph-CHO
CAS:2-Methylbiphenyl-oxadiazole-NH-Ph-CHO functions as a PD-L1 ligand for AUTACPD-L1degrader-3. It is also applicable in the synthesis of AUTAC.Formula:C22H17N3O2Color and Shape:SolidMolecular weight:355.39Ganciclovir
CAS:Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.Formula:C9H13N5O4Purity:99.4% - 99.55%Color and Shape:White PowderMolecular weight:255.23Werner syndrome RecQ helicase-IN-2
CAS:Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.Formula:C32H34F3N9O5Purity:99.02%Color and Shape:SolidMolecular weight:681.67Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4Cyclapolin 9
CAS:Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.Formula:C9H4F3N3O4SPurity:99.5%Color and Shape:SolidMolecular weight:307.21Ref: TM-T22700
1mg92.00€5mg216.00€10mg338.00€25mg540.00€50mg747.00€100mg1,017.00€500mg2,043.00€1mL*10mM (DMSO)240.00€Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurity:97.15% - 99.88%Color and Shape:White To Off-White SolidMolecular weight:354.45NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formula:C17H19Cl2N5O4SPurity:100% - 99.36%Color and Shape:SolidMolecular weight:460.33Ref: TM-TQ0068
1mg48.00€5mg97.00€10mg145.00€25mg269.00€50mg395.00€100mg563.00€200mg743.00€1mL*10mM (DMSO)99.00€Deoxyguanosine triphosphate trisodium salt
CAS:Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can beFormula:C10H13N5Na3O13P3Purity:98.73%Color and Shape:SolidMolecular weight:573.13WRN inhibitor 18
CAS:WRN inhibitor 18 (compound 306) is an orally active inhibitor of WRN with demonstrated anticancer activity in vivo.Formula:C35H35F6N5O5SColor and Shape:SolidMolecular weight:751.747-Methylxanthine
CAS:7-Methylxanthine, a xanthine methyl derivative, prevents FDM by altering the sclera in rabbits. It's a purine in kidney stones.Formula:C6H6N4O2Purity:97.66% - 98.58%Color and Shape:SolidMolecular weight:166.14sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Formula:C16H10N2OPurity:98%Color and Shape:SolidMolecular weight:246.266-Mercaptopurine hydrate
CAS:6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Formula:C5H6N4OSPurity:97.54% - 99.14%Color and Shape:Light Yellow Crystalline PowderMolecular weight:170.19Nusinersen
CAS:Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Color and Shape:SolidMirvetuximab soravtansine
CAS:Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancerPurity:95%Color and Shape:LiquidButyrolactone I
CAS:Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.Formula:C24H24O7Purity:98%Color and Shape:SolidMolecular weight:424.44CDK4/6-IN-17
CAS:CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.Formula:C27H28F4N8Purity:98%Color and Shape:SolidMolecular weight:540.56CDK9-IN-24
CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation.Formula:C27H31N3O4Purity:98%Color and Shape:SolidMolecular weight:461.55PD-1/PD-L1-IN-34
CAS:PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) effectively inhibits the PD-1/PD-L1 interaction (IC 50 = 0.029 μM) and demonstrates selective binding affinity to PD-L1Formula:C35H33ClN2O3Purity:98%Color and Shape:SolidMolecular weight:565.1CDK9-IN-28
PROTAC CDK9/CycT1 Degrader-1 (compounds 10), a potent CDK9 inhibitor, serves as a target protein ligand for PROTAC synthesis.Formula:C32H40N4O6S2Purity:98%Color and Shape:SolidMolecular weight:640.81
