Kinesin
Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.
Products of "Kinesin"
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Found 40 products on this category.
SB-743921 hydrochloride
CAS:SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formula:C31H34Cl2N2O3Purity:95.58% - 99.70%Color and Shape:SolidMolecular weight:553.52Ref: TM-T2255
1mg42.00€5mg106.00€10mg163.00€25mg278.00€50mg429.00€100mg657.00€500mg1,501.00€1mL*10mM (DMSO)130.00€KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formula:C28H38N4O5S2Purity:98.45%Color and Shape:SolidMolecular weight:574.76GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Ref: TM-T9207L
1mg131.00€5mg286.00€10mg430.00€25mg647.00€50mg969.00€100mg1,301.00€1mL*10mM (DMSO)283.00€Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formula:C20H22N4O5SPurity:99.39% - 99.39%Color and Shape:SolidMolecular weight:430.48BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3KIF18A-IN-14
CAS:KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.Formula:C26H32F3N5O6SColor and Shape:SolidMolecular weight:599.62S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47CCT251455
CAS:CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.Formula:C26H26ClN7O2Purity:99.1% - 99.1%Color and Shape:SolidMolecular weight:503.98Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formula:C26H21N3O3Purity:97.45%Color and Shape:SolidMolecular weight:423.46Ref: TM-T11155
1mg92.00€5mg205.00€10mg305.00€25mg495.00€50mg677.00€100mg905.00€200mg1,216.00€1mL*10mM (DMSO)227.00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purity:98.38%Color and Shape:SolidMolecular weight:552.43BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formula:C27H24F5N5O3Purity:95.71% - 98.78%Color and Shape:SolidMolecular weight:561.5Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.69%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg48.00€10mg62.00€25mg97.00€50mg169.00€100mg250.00€200mg373.00€500mg612.00€1mL*10mM (DMSO)52.00€TC-Mps1-12
CAS:TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Formula:C17H20N6OPurity:98%Color and Shape:SolidMolecular weight:324.38Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg43.00€5mg66.00€10mg94.00€25mg159.00€50mg230.00€100mg346.00€200mg520.00€1mL*10mM (DMSO)74.00€Litronesib
CAS:Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Formula:C23H37N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.7Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg42.00€5mg64.00€10mg92.00€25mg170.00€50mg311.00€100mg449.00€200mg630.00€1mL*10mM (DMSO)74.00€BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formula:C24H30N8OPurity:99.37%Color and Shape:SolidMolecular weight:446.55KIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Formula:C30H37N5O4SColor and Shape:SolidMolecular weight:563.71EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.53Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purity:96.24% - 99.75%Color and Shape:SolidMolecular weight:480.6UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formula:C17H17N3SPurity:99.81%Color and Shape:SolidMolecular weight:295.4GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13Ref: TM-T2039
1mg49.00€2mg70.00€5mg97.00€10mg168.00€25mg331.00€50mg510.00€100mg737.00€1mL*10mM (DMSO)136.00€GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.21PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purity:98%Color and Shape:SolidMolecular weight:554.08CFI-402257
CAS:CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.Formula:C28H30N6O3Purity:96.66% - 99.51%Color and Shape:SolidMolecular weight:498.58Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurity:98.07%Color and Shape:SolidMolecular weight:302.39Ref: TM-T3118
1mg35.00€2mg48.00€5mg62.00€10mg87.00€25mg156.00€50mg235.00€100mg354.00€1mL*10mM (DMSO)67.00€CW-069
CAS:CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formula:C23H21IN2O3Purity:97.52% - 98.59%Color and Shape:SolidMolecular weight:500.33Ref: TM-T6209
1mg43.00€5mg90.00€10mg125.00€25mg216.00€50mg306.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)89.00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFormula:C30H33ClN4O2Purity:98% - 98.59%Color and Shape:SolidMolecular weight:517.06Ref: TM-T2103
1mg39.00€2mg50.00€5mg79.00€10mg118.00€25mg210.00€50mg339.00€100mg557.00€500mg1,216.00€1mL*10mM (DMSO)89.00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.59% - 99.19%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg48.00€5mg78.00€10mg97.00€25mg188.00€50mg311.00€100mg502.00€500mg1,074.00€1mL*10mM (DMSO)87.00€(S)-Monastrol
CAS:Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98%Color and Shape:SolidMolecular weight:292.35KIF18A-IN-15
CAS:KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.Formula:C25H33F3N6O5SColor and Shape:SolidMolecular weight:586.63Kif15-IN-2
CAS:Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.Formula:C20H20N6O4SPurity:98.17%Color and Shape:SolidMolecular weight:440.48AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purity:100% - 97.84%Color and Shape:SolidMolecular weight:452.55SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81MKLP2-IN-1
CAS:MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.Formula:C23H19BrFN3O2Color and Shape:SolidMolecular weight:468.318Eg5-IN-1
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.Formula:C23H16ClFN4OPurity:98.21%Color and Shape:SolidMolecular weight:418.85K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurity:100%Color and Shape:SolidMolecular weight:277.34Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurity:97.45% - 98.44%Color and Shape:SolidMolecular weight:559.61Ref: TM-T8487
1mg90.00€5mg183.00€10mg275.00€25mg449.00€50mg615.00€100mg848.00€200mg1,121.00€1mL*10mM (DMSO)245.00€Betamethasone 17-benzoate
CAS:Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formula:C29H33FO6Purity:98%Color and Shape:SolidMolecular weight:496.57PVZB1194
CAS:PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormula:C13H9F4NO2SPurity:98%Color and Shape:SolidMolecular weight:319.28
