LIM Kinase
LIM kinase inhibitors target LIM kinases, a family of enzymes involved in the regulation of the actin cytoskeleton and cell cycle progression. LIM kinases phosphorylate and inactivate cofilin, a protein that disassembles actin filaments, thus controlling cell shape, motility, and division. Inhibiting LIM kinases can affect these processes, leading to altered cell cycle dynamics and potential apoptosis. LIM kinase inhibitors are important tools in cancer research and the study of cell motility and invasion. At CymitQuimica, we provide a selection of high-quality LIM kinase inhibitors to support your research in cell signaling, cytoskeletal dynamics, and oncology.
Products of "LIM Kinase"
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Found 9 products on this category.
LIMK-IN-22j
CAS:LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.Formula:C20H21BrN8Purity:99.17%Color and Shape:SolidMolecular weight:453.34BMS-5
CAS:BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formula:C17H14Cl2F2N4OSPurity:95.83% - 99.88%Color and Shape:SolidMolecular weight:431.29Ref: TM-T4598
1mg43.00€2mg55.00€5mg84.00€10mg123.00€25mg198.00€50mg298.00€100mg444.00€1mL*10mM (DMSO)92.00€T56-LIMKi
CAS:T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.Formula:C19H14F3N3O3Purity:98.39% - 98.61%Color and Shape:SolidMolecular weight:389.33CRT-0105950
CAS:CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Formula:C21H16ClN3OSPurity:99.78% - 99.86%Color and Shape:SolidMolecular weight:393.89Ref: TM-T23917
1mg65.00€5mg140.00€10mg216.00€25mg439.00€50mg707.00€100mg1,130.00€1mL*10mM (DMSO)156.00€BMS-3
CAS:BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.Formula:C17H12Cl2F2N4OSPurity:99.19% - 99.31%Color and Shape:SolidMolecular weight:429.27TH-257
CAS:TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).Formula:C24H26N2O3SPurity:98.23%Color and Shape:SolidMolecular weight:422.54Damnacanthal
CAS:Damnacanthal is a natural anthraquinone with potential anticancer property, inhibiting a variety of protein kinases such as LIMK1, LIMK2 and Lck.Formula:C16H10O5Purity:98%Color and Shape:SolidMolecular weight:282.25LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86Ref: TM-T12609
1mg75.00€5mg170.00€10mg256.00€25mg423.00€50mg562.00€100mg792.00€200mg1,074.00€1mL*10mM (DMSO)182.00€
