Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Products of "Microtubule Associated"
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KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.Formula:C18H21N5SPurity:98.00%Color and Shape:SolidMolecular weight:339.46LY3372689
CAS:LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.Formula:C16H22FN5O3SPurity:99.27% - 99.45%Color and Shape:SolidMolecular weight:383.44Ref: TM-T61661
1mg99.00€5mg235.00€10mg354.00€25mg635.00€50mg935.00€100mg1,415.00€1mL*10mM (DMSO)259.00€Ansamitocin P 3'
CAS:Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.Formula:C32H43ClN2O9Purity:98.16% - 99.16%Color and Shape:SolidMolecular weight:635.14Ref: TM-T1910
2mg34.00€5mg50.00€10mg84.00€25mg145.00€50mg229.00€100mg340.00€200mg472.00€1mL*10mM (DMSO)70.00€Tubulysin D
CAS:Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.Formula:C43H65N5O9SPurity:98%Color and Shape:SolidMolecular weight:828.07Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Formula:C17H19N5O2Purity:98%Color and Shape:SolidMolecular weight:325.37CK-869
CAS:CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.Formula:C17H16BrNO3SPurity:99.85%Color and Shape:SolidMolecular weight:394.28BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Ref: TM-T14694
1mg84.00€5mg160.00€10mg226.00€25mg371.00€50mg520.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)170.00€WAY-118959-A
CAS:WAY-118959-A is a potential microtubule acetylation inhibitor.Formula:C16H14N4OS2Purity:99.86%Color and Shape:SolidMolecular weight:342.44Ref: TM-T60065
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€200mg1,454.00€1mL*10mM (DMSO)261.00€Ombrabulin hydrochloride
CAS:Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells andFormula:C21H27ClN2O6Purity:98%Color and Shape:SolidMolecular weight:438.9TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Formula:C19H18N2O2Purity:99.54%Color and Shape:SolidMolecular weight:306.36Auristatin F
CAS:Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.Formula:C40H67N5O8Purity:98.41% - 99.25%Color and Shape:SolidMolecular weight:745.99AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Formula:C26H35N5O5SPurity:98.06% - 99.58%Color and Shape:SolidMolecular weight:529.65MMAF
CAS:MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.Formula:C39H65N5O8Purity:97.00%Color and Shape:SolidMolecular weight:731.96Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Formula:C11H17N2O4PSPurity:99.66%Color and Shape:SolidMolecular weight:304.3JH-VIII-157-02
CAS:JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.Formula:C28H27N5O2Purity:98.02%Color and Shape:SolidMolecular weight:465.55Ref: TM-T15612
1mg116.00€5mg240.00€10mg358.00€25mg558.00€50mg753.00€100mg1,035.00€1mL*10mM (DMSO)246.00€Mertansine
CAS:Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.Cost-effective and quality-assured.Formula:C35H48ClN3O10SPurity:100% - 99.76%Color and Shape:SolidMolecular weight:738.29Cevipabulin
CAS:Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFormula:C18H18ClF5N6OPurity:99.53%Color and Shape:SolidMolecular weight:464.82Plinabulin
CAS:Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Formula:C19H20N4O2Purity:100% - 98.69%Color and Shape:SolidMolecular weight:336.39S516
CAS:S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Formula:C21H19N5O4SPurity:98%Color and Shape:SolidMolecular weight:437.47Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85Ref: TM-T13224
5mg50.00€10mg80.00€25mg117.00€50mg170.00€100mg259.00€200mg369.00€1mL*10mM (DMSO)51.00€Suprafenacine
CAS:Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that inducesFormula:C16H18N4OPurity:99.72%Color and Shape:SolidMolecular weight:282.34SB-216
CAS:SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.Formula:C17H18N4O2Purity:100%Color and Shape:SolidMolecular weight:310.35Ref: TM-T60757
1mg54.00€5mg116.00€10mg188.00€25mg331.00€50mg475.00€100mg655.00€1mL*10mM (DMSO)133.00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99.42%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg38.00€5mg56.00€10mg70.00€25mg126.00€50mg243.00€100mg416.00€200mg562.00€1mL*10mM (DMSO)65.00€Tubulin inhibitor 8
CAS:Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.Formula:C21H14N2O3Purity:100% - 99.34%Color and Shape:SolidMolecular weight:342.35TTBK1-IN-2
CAS:TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.Formula:C18H13ClN4OPurity:99.83%Color and Shape:SoildMolecular weight:336.77Ref: TM-T60086
1mg81.00€5mg168.00€10mg240.00€25mg399.00€50mg567.00€100mg758.00€200mg1,017.00€1mL*10mM (DMSO)170.00€Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Ref: TM-T6345
1mg35.00€5mg66.00€10mg81.00€25mg159.00€50mg280.00€100mg470.00€500mg1,035.00€1mL*10mM (DMSO)70.00€Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formula:C23H31Cl2NO3Purity:98.09%Color and Shape:SolidMolecular weight:440.4Ref: TM-T20681
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg329.00€200mg487.00€1mL*10mM (DMSO)50.00€Parbendazole
CAS:Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.Formula:C13H17N3O2Purity:99.60%Color and Shape:Physical Description Crystals Or Fine White Powder (Ntp 1992)Molecular weight:247.29Tubulin inhibitor 1
CAS:Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Formula:C21H24N2O4Purity:98%Color and Shape:SolidMolecular weight:368.43Eribulin
CAS:Eribulin binds microtubules, halts cancer cell growth, treating metastatic breast cancer.Formula:C40H59NO11Purity:99.96%Color and Shape:SolidMolecular weight:729.90Tasidotin hydrochloride
CAS:Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Formula:C32H59ClN6O5Purity:98%Color and Shape:SolidMolecular weight:643.30DM1-SMe
CAS:DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.Formula:C36H50ClN3O10S2Purity:97.19%Color and Shape:SolidMolecular weight:784.38Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg50.00€10mg78.00€25mg145.00€50mg210.00€100mg300.00€200mg434.00€1mL*10mM (DMSO)56.00€Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Formula:C25H20N2O7Purity:100%Color and Shape:SolidMolecular weight:460.44Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formula:C12H15N3O3SPurity:98.04%Color and Shape:White To Off-White PowderMolecular weight:281.33Thiocolchicine
CAS:Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.Formula:C22H25NO5SPurity:98.19%Color and Shape:SolidMolecular weight:415.5KG-548
CAS:KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.Formula:C9H4F6N4Purity:99.62%Color and Shape:SolidMolecular weight:282.15Tubulin polymerization-IN-55
CAS:Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.Formula:C22H24N2O4Purity:98.68%Color and Shape:SoildMolecular weight:380.44T807
CAS:T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).Formula:C16H10FN3Purity:99.72%Color and Shape:SolidMolecular weight:263.27Ref: TM-T19573
2mg47.00€5mg70.00€10mg107.00€25mg187.00€50mg323.00€100mg550.00€200mg758.00€500mg1,159.00€Dihydrocytochalasin B
CAS:Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.Formula:C29H39NO5Purity:98%Color and Shape:SolidMolecular weight:481.62Pironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formula:C14H9N3OPurity:99.51%Color and Shape:SolidMolecular weight:235.24Ref: TM-T10704
1mg115.00€5mg274.00€10mg432.00€25mg845.00€50mg1,293.00€100mg1,768.00€1mL*10mM (DMSO)303.00€N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFormula:C24H18ClN3OPurity:98.65%Color and Shape:SoildMolecular weight:399.87Ref: TM-T60041
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€200mg1,454.00€1mL*10mM (DMSO)279.00€Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Formula:C12H14O5Purity:98.97%Color and Shape:SolidMolecular weight:238.24Ref: TM-T36850
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)284.00€MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.Formula:C19H17NO4Purity:99.56%Color and Shape:SolidMolecular weight:323.34S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Formula:C36H50ClN3O10SPurity:98%Color and Shape:SolidMolecular weight:752.31CID-663143
CAS:CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.Formula:C19H18N4O2SPurity:99.56% - 99.68%Color and Shape:SolidMolecular weight:366.44Ref: TM-T23889
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)164.00€Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Formula:C39H67N5O6Purity:97.48%Color and Shape:SolidMolecular weight:701.98MT189
CAS:MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.Formula:C21H18FN3O2Purity:98.67%Color and Shape:SoildMolecular weight:363.38LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Formula:C22H19N3O4SPurity:99.76%Color and Shape:SolidMolecular weight:421.47Ref: TM-T9595
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€1mL*10mM (DMSO)87.00€
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