c-Myc
c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.
Products of "c-Myc"
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Found 44 products on this category.
KSI-3716
CAS:KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.Formula:C17H11BrCl2N2O2Purity:98.94%Color and Shape:SolidMolecular weight:426.09BRD4 Inhibitor-40
CAS:BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.Formula:C27H32N8OColor and Shape:SolidMolecular weight:484.596β-catenin-IN-8
CAS:β-catenin-IN-8 (Compound 25) is an inhibitor of β-catenin. It effectively lowers the levels of both β-catenin and c-Myc proteins and suppresses Wnt target genes (Fgf20 and Sall4). Additionally, β-catenin-IN-8 exhibits anticancer activity against colorectal cancer and possesses metabolic stability.Formula:C15H12ClN3O2SColor and Shape:SolidMolecular weight:333.79NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.76Ref: TM-T9093
1mg87.00€5mg187.00€10mg298.00€25mg525.00€50mg747.00€100mg1,017.00€1mL*10mM (DMSO)264.00€Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.7510058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.82%Color and Shape:SolidMolecular weight:249.35WBC100
CAS:WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathwayFormula:C25H33NO7Purity:98%Color and Shape:SolidMolecular weight:459.53Lusianthridin
CAS:Lusianthridin is a natural product from Dendrobium venustum.Formula:C15H14O3Purity:99.11% - 99.11%Color and Shape:SolidMolecular weight:242.272-5A-dependent Rnase Protein, Human, Recombinant (Myc)
2-5A-dependent Rnase Protein, Human, Recombinant (Myc) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:85.1 kDa (predicted)MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tetheredFormula:C55H58N10O11SPurity:98%Color and Shape:SolidMolecular weight:1067.17Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Formula:C22H14FN5Purity:98.73%Color and Shape:SolidMolecular weight:367.38Ref: TM-T10352
1mg43.00€2mg55.00€5mg80.00€10mg101.00€25mg180.00€50mg284.00€100mg411.00€200mg597.00€1mL*10mM (DMSO)88.00€c-Myc inhibitor 12
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].Formula:C22H24N6OPurity:98%Color and Shape:SolidMolecular weight:388.4710074-A4
CAS:10074-A4 is a c-Myc binding compound that associates with c-Myc370-409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features fromFormula:C18H14Cl2N2O3SPurity:98.01%Color and Shape:SolidMolecular weight:409.29Ref: TM-T9628
1mg71.00€5mg135.00€10mg197.00€25mg335.00€50mg480.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)156.00€PARL Protein, Human, Recombinant (Myc)
Required for the control of apoptosis during postnatal growth.Color and Shape:Lyophilized PowderMolecular weight:37.8 kDa (predicted)MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.58%Color and Shape:SolidMolecular weight:561.310074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:97.22% - 99.67%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg42.00€5mg63.00€10mg88.00€25mg142.00€50mg225.00€100mg396.00€200mg565.00€500mg900.00€1mL*10mM (DMSO)69.00€Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Formula:C15H20O5Purity:99.58%Color and Shape:SolidMolecular weight:280.32Ref: TM-T21065
1mg95.00€5mg187.00€10mg329.00€25mg560.00€50mg800.00€100mg1,103.00€1mL*10mM (DMSO)281.00€Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purity:99.61% - 99.9%Color and Shape:SolidMolecular weight:138.12Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:100% - 99.93%Color and Shape:SolidMolecular weight:533.95m-Se3
CAS:m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].Formula:C29H23IN2SePurity:98%Color and Shape:SolidMolecular weight:605.37MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formula:C26H16ClF9N2O2Purity:99.52%Color and Shape:SolidMolecular weight:594.86sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Formula:C16H10N2OPurity:98%Color and Shape:SolidMolecular weight:246.26(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35ACOX1 Protein, Mouse, Recombinant (Myc)
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.Color and Shape:Lyophilized PowderMolecular weight:76.2 kDa (predicted)KJ Pyr 9
CAS:KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formula:C22H15N3O4Purity:98.07% - ≥98%Color and Shape:SolidMolecular weight:385.37Ref: TM-T15665
2mg39.00€5mg57.00€10mg81.00€25mg145.00€50mg279.00€100mg510.00€200mg683.00€500mg1,064.00€1mL*10mM (DMSO)63.00€CSI86
CSI86 is a PROTAC degrader targeting MYC, exhibiting antiproliferative activity (IC50: 13-18 μM).Formula:C48H50F9N7O7SColor and Shape:SolidMolecular weight:1040IRES-C11
CAS:IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Formula:C13H11Cl2NO4Purity:99.89%Color and Shape:SolidMolecular weight:316.14Ref: TM-T40419
1mg103.00€5mg246.00€10mg395.00€25mg785.00€50mg1,198.00€100mg1,853.00€200mg2,498.00€1mL*10mM (DMSO)271.00€EN4
CAS:EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Formula:C25H24N2O4Purity:98.51%Color and Shape:SolidMolecular weight:416.47Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purity:97.87% - 99.51%Color and Shape:SolidMolecular weight:526.88Ref: TM-T4367
1mg49.00€5mg99.00€10mg168.00€25mg335.00€50mg477.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)116.00€MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].Formula:C35H38N4O7SPurity:98%Color and Shape:SolidMolecular weight:658.76c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in ratFormula:C20H22N6OPurity:98%Color and Shape:SolidMolecular weight:362.43BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formula:C12H9BrN2OSPurity:99.91% - ≥95%Color and Shape:SolidMolecular weight:309.18Ref: TM-T9033
5mg48.00€10mg63.00€25mg93.00€50mg136.00€100mg198.00€200mg309.00€500mg563.00€1mL*10mM (DMSO)50.00€MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Formula:C20H19N7OPurity:99.23%Color and Shape:SolidMolecular weight:373.41Ref: TM-T12134
1mg74.00€5mg160.00€10mg235.00€25mg378.00€50mg540.00€100mg747.00€200mg1,026.00€500mg1,510.00€VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Formula:C16H12F6N2SPurity:99.93%Color and Shape:SolidMolecular weight:378.34Ref: TM-T60019
1mg51.00€5mg106.00€10mg160.00€25mg283.00€50mg406.00€100mg592.00€200mg835.00€1mL*10mM (DMSO)137.00€FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormula:C16H15F2NPurity:97.75%Color and Shape:SolidMolecular weight:259.29Ref: TM-T11284
5mg52.00€10mg78.00€25mg134.00€50mg192.00€100mg279.00€200mg374.00€1mL*10mM (DMSO)50.00€Eragidomide
CAS:Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.Formula:C22H18ClF2N3O4Purity:97.51% - 99.63%Color and Shape:SolidMolecular weight:461.85Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purity:98.05% - 99.95%Color and Shape:SolidMolecular weight:315.41FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurity:97.66% - 98.3%Color and Shape:SolidMolecular weight:261.72Ref: TM-T11285
1mg59.00€2mg85.00€5mg116.00€10mg187.00€25mg331.00€50mg512.00€100mg740.00€500mg1,415.00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:98.31% - ≥95%Color and Shape:SolidMolecular weight:284.31Aaptamine
CAS:Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.Formula:C13H12N2O2Purity:98%Color and Shape:SolidMolecular weight:228.25Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formula:C36H71NO4Purity:98%Color and Shape:SolidMolecular weight:581.967NNK
CAS:NNK is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.Cost-effective and quality-assured.Formula:C10H13N3O2Purity:98.89% - 99.86%Color and Shape:SolidMolecular weight:207.23Ref: TM-T20533
5mg60.00€10mg96.00€25mg159.00€50mg227.00€100mg274.00€200mg406.00€500mg652.00€1mL*10mM (DMSO)65.00€ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purity:99.48%Color and Shape:SolidMolecular weight:366.37
