HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Products of "HSP"
Sort by
Ganetespib
CAS:Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formula:C20H20N4O3Purity:97.29% - 99.95%Color and Shape:SolidMolecular weight:364.4Ref: TM-T2309
5mg66.00€10mg87.00€25mg133.00€50mg166.00€100mg250.00€200mg424.00€500mg702.00€1mL*10mM (DMSO)74.00€Teprenone
CAS:Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Formula:C23H38OPurity:99.76% - 99.96%Color and Shape:SolidMolecular weight:330.55SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurity:98%Color and Shape:SolidMolecular weight:718.02Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purity:99.9% - 99.98%Color and Shape:SolidMolecular weight:429.85Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Formula:C22H18BrCl2N3OS4Purity:99.21%Color and Shape:SolidMolecular weight:619.47DDO-5936
CAS:DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59Ref: TM-T9202
1mg37.00€5mg80.00€10mg126.00€25mg264.00€50mg389.00€100mg553.00€200mg750.00€1mL*10mM (DMSO)88.00€HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Formula:C26H27ClN4O2Purity:97.15%Color and Shape:SolidMolecular weight:462.97L-Alanyl-L-glutamine
CAS:L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.Formula:C8H15N3O4Purity:99.71% - 99.97%Color and Shape:SolidMolecular weight:217.22Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Formula:C16H32O2Purity:99.17% - 99.67%Color and Shape:White Crystalline Scales SolidMolecular weight:256.42C086
CAS:C086 is a novel and potent Hsp90 inhibitor that suppresses cell cycle progression, induces apoptosis, and exhibits anti-metastatic properties by modulating various mechanisms in different cell types.Formula:C29H28O8Color and Shape:SolidMolecular weight:504.53HSP90-IN-27
CAS:HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].Formula:C18H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:343.44Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formula:C32H48N4O8Purity:100%Color and Shape:SolidMolecular weight:616.75NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Formula:C32H32FN5O4Purity:99.26%Color and Shape:SolidMolecular weight:569.63Ref: TM-T9804
1mg96.00€5mg240.00€10mg375.00€25mg627.00€50mg893.00€100mg1,216.00€1mL*10mM (DMSO)300.00€Radicicol
CAS:Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Formula:C18H17ClO6Purity:98%Color and Shape:White/Yellow PowderMolecular weight:364.78Azadiradione
CAS:Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indicaFormula:C28H34O5Purity:99.52% - 99.52%Color and Shape:SolidMolecular weight:450.57Ref: TM-TN6729
1mg131.00€5mg286.00€10mg515.00€25mg777.00€50mg1,074.00€100mg1,454.00€1mL*10mM (DMSO)354.00€GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formula:C17H18N4O2SPurity:99.11%Color and Shape:SoildMolecular weight:342.42IPI-493
CAS:IPI-493 is a bioactive chemical.Formula:C28H39N3O8Purity:100%Color and Shape:SolidMolecular weight:545.62VER-49009
CAS:VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82Ref: TM-T3454
2mg46.00€5mg64.00€10mg92.00€25mg164.00€50mg259.00€100mg354.00€200mg500.00€1mL*10mM (DMSO)52.00€Pimitespib
CAS:Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Formula:C25H26N8OPurity:99.22% - 99.49%Color and Shape:SolidMolecular weight:454.53NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.Formula:C31H35F3N2O5SPurity:98%Color and Shape:SolidMolecular weight:604.68Paeoniflorin
CAS:Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Formula:C23H28O11Purity:96.9% - 97.16%Color and Shape:White Fine PowderMolecular weight:480.46Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Formula:C24H18F3N5O3Color and Shape:SolidMolecular weight:481.43Tanespimycin
CAS:Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:97.34% - 98.54%Color and Shape:SolidMolecular weight:489.47Calyxin H
CAS:Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.Formula:C35H34O7Purity:98%Color and Shape:SolidMolecular weight:566.64SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formula:C22H26FN3O3Purity:99.86%Color and Shape:SolidMolecular weight:399.46Ref: TM-T28824
1mg89.00€5mg188.00€10mg316.00€25mg512.00€50mg702.00€100mg940.00€500mgTo inquire1mL*10mM (DMSO)207.00€7-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurity:91.05% - 98.22%Color and Shape:White Solid PowderMolecular weight:272.28HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.Formula:C22H24N2O6SPurity:98%Color and Shape:SolidMolecular weight:444.5DN401
CAS:DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.Formula:C13H9BrClN5O2Purity:100%Color and Shape:SolidMolecular weight:382.6Ref: TM-T27193
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)406.00€TRAP1-IN-2
CAS:TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients.Formula:C46H42F6N2O5P2Purity:98%Color and Shape:SolidMolecular weight:878.77Ethoxyquin
CAS:Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formula:C14H19NOPurity:95.94%Color and Shape:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Molecular weight:217.31Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.81%Color and Shape:SolidMolecular weight:313.78Ref: TM-T13553
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)249.00€AT-533
CAS:AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Formula:C23H30N4O3Purity:99.54%Color and Shape:SoildMolecular weight:410.51Ref: TM-T67836
1mg51.00€5mg111.00€10mg170.00€25mg313.00€50mg467.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)117.00€Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61Grp94 Inhibitor-1
CAS:Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).Formula:C22H28N2O2Purity:97.02%Color and Shape:SolidMolecular weight:352.47PF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Ref: TM-T4342
1mg78.00€2mg100.00€5mg159.00€10mg288.00€25mg419.00€50mg615.00€100mg878.00€500mg1,776.00€1mL*10mM (DMSO)233.00€HS-27
CAS:HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Formula:C52H60N6O12SPurity:97.09%Color and Shape:SolidMolecular weight:993.13Ref: TM-T18018
1mg90.00€5mg215.00€10mg344.00€25mg612.00€50mg848.00€100mg1,159.00€1mL*10mM (DMSO)378.00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:98.05% - 99.82%Color and Shape:SolidMolecular weight:409.5217-AEP-GA
CAS:17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.Formula:C34H50N4O8Purity:97.77% - 99.56%Color and Shape:SolidMolecular weight:642.78Apoptozole
CAS:Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.Formula:C33H25F6N3O3Purity:99.75%Color and Shape:SolidMolecular weight:625.56Ref: TM-T3293
2mg35.00€5mg50.00€10mg84.00€25mg137.00€50mg235.00€100mg349.00€200mg515.00€1mL*10mM (DMSO)66.00€VER49009
CAS:VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).Formula:C19H18ClN3O4Purity:100% - 99.17%Color and Shape:SolidMolecular weight:387.82Ref: TM-T2268
1mg60.00€2mg85.00€5mg111.00€10mg167.00€25mg283.00€50mg472.00€100mg643.00€1mL*10mM (DMSO)96.00€KU-32
CAS:KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Formula:C20H25NO8Purity:98%Color and Shape:SolidMolecular weight:407.41HSP90-IN-22
CAS:HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFormula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formula:C29H37N5O3Purity:98.1%Color and Shape:SolidMolecular weight:503.64PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.Formula:C43H50N6O7Purity:98%Color and Shape:SolidMolecular weight:762.89VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.Formula:C25H23Cl2N7O4Purity:98.88% - 99.55%Color and Shape:SolidMolecular weight:556.4Ref: TM-T7010
2mg47.00€5mg69.00€10mg93.00€25mg163.00€50mg283.00€100mg467.00€200mg653.00€1mL*10mM (DMSO)85.00€CYP51/Hsp90-IN-1
CYP51/Hsp90-IN-1 (Compound MM4) is a dual inhibitor of CYP51 and Hsp90. This compound exhibits antifungal activity against Candida albicans and effectively suppresses key fungal virulence factors. CYP51/Hsp90-IN-1 shows potential for research in treating invasive candidiasis.Formula:C38H40F2N6O4Color and Shape:SolidMolecular weight:682.76KW-2478
CAS:KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.Formula:C30H42N2O9Purity:98.68% - 99.52%Color and Shape:SolidMolecular weight:574.66Ref: TM-T6558
1mg56.00€2mg81.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg662.00€1mL*10mM (DMSO)205.00€
