Rho
Rho inhibitors target the Rho family of GTPases, which are critical regulators of the cytoskeleton, cell division, and signal transduction pathways. Rho GTPases are involved in controlling the dynamics of actin filaments, cell shape, and motility, as well as progression through the cell cycle. Dysregulation of Rho signaling can lead to uncontrolled cell proliferation and cancer. Inhibiting Rho GTPases can induce cell cycle arrest and apoptosis, making these inhibitors valuable tools in cancer research and the study of cell motility. At CymitQuimica, we offer a range of high-quality Rho inhibitors to support your research in cell cycle regulation, cytoskeletal dynamics, and oncology.
Products of "Rho"
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Found 15 products on this category.
Rhosin
CAS:Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not affecting Cdc42/Rac1/LARG, and induces apoptosis.Formula:C20H18N6OPurity:98%Color and Shape:SolidMolecular weight:358.4CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ref: TM-T7764
2mg42.00€5mg65.00€10mg99.00€25mg182.00€50mg279.00€100mg414.00€200mg587.00€1mL*10mM (DMSO)70.00€(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formula:C23H15F3N2O4Purity:95.83%Color and Shape:SolidMolecular weight:440.37Ref: TM-T9986
1mg66.00€5mg145.00€10mg221.00€25mg378.00€50mg533.00€100mg718.00€200mg938.00€1mL*10mM (DMSO)160.00€CCG-257081
CAS:CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.Formula:C24H19ClF3N3O2Purity:98% - 99.92%Color and Shape:SolidMolecular weight:473.87EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg48.00€10mg73.00€25mg127.00€50mg213.00€100mg334.00€200mg492.00€500mg787.00€1mL*10mM (DMSO)52.00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purity:99.58%Color and Shape:SolidMolecular weight:478.82Ref: TM-T22062
5mg38.00€10mg57.00€25mg114.00€50mg188.00€100mg303.00€200mg449.00€1mL*10mM (DMSO)43.00€CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purity:98.82% - 99.35%Color and Shape:SolidMolecular weight:408.88ML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Formula:C14H13NO2SPurity:99.48%Color and Shape:SolidMolecular weight:259.32Ref: TM-T22991
1mg48.00€2mg64.00€5mg96.00€10mg153.00€25mg305.00€50mg487.00€100mg710.00€1mL*10mM (DMSO)94.00€NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formula:C24H35N7Purity:99.49%Color and Shape:SolidMolecular weight:421.58Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46Ref: TM-T37113
1mg38.00€5mg80.00€10mg111.00€25mg183.00€50mg269.00€100mg393.00€200mg560.00€1mL*10mM (DMSO)92.00€1A-116
CAS:1A-116 is a specific Rac1 inhibitor.Formula:C16H16F3N3Purity:98.43%Color and Shape:SolidMolecular weight:307.31Ref: TM-T14004
1mg50.00€5mg111.00€10mg166.00€25mg283.00€50mg444.00€100mg655.00€200mg924.00€1mL*10mM (DMSO)123.00€Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4MLS000532223
CAS:MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).Formula:C15H9NO3Purity:98.60%Color and Shape:SolidMolecular weight:251.24Ref: TM-T8473
1mg130.00€2mg183.00€5mg306.00€10mg462.00€25mg755.00€50mg1,035.00€100mg1,415.00€1mL*10mM (DMSO)319.00€EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Ref: TM-T6483
1mg47.00€5mg92.00€10mg136.00€25mg259.00€50mg472.00€100mg677.00€200mg934.00€1mL*10mM (DMSO)107.00€ITX3
CAS:ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Formula:C22H17N3OSPurity:99.02%Color and Shape:SolidMolecular weight:371.45
