RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Products of "RAAS"
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Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Formula:C22H23ClN6OPurity:100% - 99.79%Color and Shape:Off White Solid PowderMolecular weight:422.91Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Formula:C32H29NO5Purity:94.13%Color and Shape:SolidMolecular weight:507.58Telmisartan
CAS:Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Formula:C33H30N4O2Purity:99.88% - 99.96%Color and Shape:White Or Off White Crystalline PowderMolecular weight:514.62Vicenin 3
CAS:Vicenin 3 is an inhibitor of angiotensin-converting enzyme (ACE; IC50: 46.91 μM) from the aerial parts of Desmodium styracifolium.Formula:C26H28O14Purity:100% - 99.8%Color and Shape:SolidMolecular weight:564.49Ref: TM-T13299
1mg74.00€5mg160.00€10mg259.00€25mg435.00€50mg630.00€100mg880.00€1mL*10mM (DMSO)207.00€Pivalopril
CAS:Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.Formula:C16H27NO4SPurity:98%Color and Shape:SolidMolecular weight:329.45Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Formula:C32H40N4O5SPurity:97.94% - 98.75%Color and Shape:SolidMolecular weight:592.75Ref: TM-T5355
2mg39.00€5mg58.00€10mg94.00€25mg170.00€50mg259.00€100mg380.00€200mg540.00€1mL*10mM (DMSO)77.00€ME-3221
CAS:Apomine inhibits HMG-CoA-reductase, induces myeloma cell apoptosis, modulates myeloma, and boosts lovastatin's antitumor effects.Formula:C22H21N5O2Purity:100% - 99.84%Color and Shape:SolidMolecular weight:387.43Enalapril Maleate
CAS:Enalapril Maleate (MK-421 Maleate), an ACE inhibitor, is utilized in the treatment of hypertension, chronic heart failure, and diabetic nephropathy.Formula:C20H28N2O5·C4H4O4Purity:99.02% - ≥95%Color and Shape:White To Off-White Crystalline Powder SolidMolecular weight:492.52Losartan Carboxylic Acid
CAS:Losartan Carboxylic Acid (E-3174) is a potent AT1 blocker with vasodilatory effects, stronger than losartan, with Kis of 0.57 nM in rats and 0.67 nM in humans.Formula:C22H21ClN6O2Purity:98.36% - 99.28%Color and Shape:Light-Yellow SolidMolecular weight:436.89Nesvacumab
CAS:Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.Purity:95% - >95%Color and Shape:LiquidNitrosoglutathione
CAS:Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins.Formula:C10H16N4O7SPurity:99.61% - 99.68%Color and Shape:Pink PowderMolecular weight:336.32VTP-27999 TFA
CAS:VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).Formula:C28H42ClF3N4O7Purity:99.72%Color and Shape:SolidMolecular weight:639.1Benazeprilat
CAS:Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combinationFormula:C22H24N2O5Purity:98.35%Color and Shape:Crystalline SolidMolecular weight:396.44Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formula:C42H55F3N8O10Purity:98%Color and Shape:SolidMolecular weight:888.93Valsartan
CAS:Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.Formula:C24H29N5O3Purity:99.24% - 99.76%Color and Shape:White Solid PowderMolecular weight:435.52Peimisine
CAS:Peimisine acts on receptors, modulates calcium and nitric oxide, easing asthma, reduces lung injury and fibrosis, and might lower blood pressure.Formula:C27H41NO3Purity:98.99% - 99.26%Color and Shape:SolidMolecular weight:427.62Ref: TM-T5S0106
1mg43.00€5mg90.00€10mg117.00€25mg192.00€50mg283.00€100mg419.00€1mL*10mM (DMSO)105.00€[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2A 779 TFA(159432-28-7 free base)
A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.Formula:C41H61F3N12O13Purity:99.55%Color and Shape:SolidMolecular weight:987.01Enalapril
CAS:Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.Formula:C20H28N2O5Purity:99.47%Color and Shape:SolidMolecular weight:376.45BIBS 39
CAS:BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Formula:C32H36N4O3Purity:98%Color and Shape:SolidMolecular weight:524.65
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