GPR
G protein-coupled receptors (GPRs) are a large family of cell surface receptors that play a crucial role in transmitting signals from hormones, neurotransmitters, and other extracellular ligands into the cell. GPRs are involved in a wide range of physiological processes, including hormone regulation, immune response, and sensory perception. Modulating GPR activity is a key strategy in the development of therapeutics for various diseases, including endocrine disorders, cardiovascular diseases, and neurological conditions. At CymitQuimica, we offer a selection of high-quality GPR modulators to support your research in cell signaling, endocrinology, and drug discovery.
Products of "GPR"
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GPR84 antagonist 8
CAS:GPR84 antagonist 8 is a selective GPR84 antagonist.Formula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45TC-O 9311 free base
CAS:TC-O 9311 is a potent GPR139 agonist.Formula:C20H19N3O4Purity:99.24%Color and Shape:SoildMolecular weight:365.39Ref: TM-T4626
Discontinued productMS 15203
CAS:MS 15203 is a GPR171 agonist that reduces chronic neuropathic and inflammatory pain in male mice.Formula:C12H11NO5Purity:99.53%Color and Shape:SolidMolecular weight:249.22Ref: TM-T37131
2mg46.00€5mg66.00€10mg104.00€25mg210.00€50mg311.00€100mg467.00€500mg1,017.00€1mL*10mM (DMSO)74.00€Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Formula:C24H19FN2O3Purity:99.16%Color and Shape:SolidMolecular weight:402.42AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35TAK-875 Hemihydrate
CAS:TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.Formula:C29H32O7SH2OPurity:98%Color and Shape:SolidMolecular weight:533.63GSK137647A
CAS:GSK137647A (GSK 137647) is a selective FFA4 agonist.Formula:C16H19NO3SPurity:99.26% - 99.87%Color and Shape:SolidMolecular weight:305.39Ref: TM-T3171
2mg35.00€5mg51.00€10mg85.00€25mg155.00€50mg245.00€100mg424.00€200mg613.00€500mg938.00€1mL*10mM (DMSO)57.00€MK 1903
CAS:MK 1903 is a strong, selective HCA2/GPR109A agonist, reducing cAMP in CHO cells with EC50 of 12.9 nM.Formula:C8H8N2O2Purity:99.87%Color and Shape:SolidMolecular weight:164.16VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.Formula:C25H23Cl2N7O4Purity:98.88% - 99.55%Color and Shape:SolidMolecular weight:556.4Ref: TM-T7010
2mg47.00€5mg69.00€10mg93.00€25mg163.00€50mg283.00€100mg467.00€200mg653.00€1mL*10mM (DMSO)85.00€ATC 0175 hydrochloride
CAS:ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.Formula:C23H26ClF2N5OPurity:99.84%Color and Shape:SolidMolecular weight:461.93Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purity:97.99%Color and Shape:SolidMolecular weight:760.821-methoxycyclopropanecarboxylic acid
CAS:1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).Formula:C5H8O3Purity:99.44%Color and Shape:Light-Yellow To Yellow Solid Or LiquidMolecular weight:116.12GPR35 agonist 2
CAS:GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM,Formula:C17H11FN2O3SPurity:97.18% - 98.40%Color and Shape:SolidMolecular weight:342.34Ref: TM-T23434
1mg52.00€5mg96.00€10mg170.00€25mg378.00€50mg560.00€100mg800.00€500mg1,644.00€1mL*10mM (DMSO)114.00€GPR120 Agonist 1
CAS:GPR120 Agonist 1 selectively activates human/mouse GPR120 with EC50 of 42/77 nM in HEK293 cells.Formula:C20H12ClF6NO3SPurity:98%Color and Shape:SolidMolecular weight:495.823-chloro-5-hydroxybenzoic Acid
CAS:3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)Formula:C7H5ClO3Purity:98%Color and Shape:SolidMolecular weight:172.57AH-7614
CAS:AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.Formula:C20H17NO3SPurity:98.05%Color and Shape:SolidMolecular weight:351.42Ref: TM-T22027
5mg51.00€10mg90.00€25mg173.00€50mg311.00€100mg424.00€200mg552.00€500mg715.00€1mL*10mM (DMSO)64.00€TUG-1375
CAS:TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2Formula:C22H19ClN2O4SPurity:97.72% - 99.41%Color and Shape:SolidMolecular weight:442.92Ref: TM-T7796
1mg133.00€5mg323.00€10mg527.00€25mg822.00€50mg1,103.00€100mg1,483.00€500mg2,965.00€1mL*10mM (DMSO)354.00€D-Kynurenine
CAS:D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.Formula:C10H12N2O3Purity:97.08%Color and Shape:SolidMolecular weight:208.21Kynurenic acid
CAS:Kynurenic acid (Quinurenic acid) is an NMDA, glutamate, α7 nicotinic acetylcholine receptor triple antagonist and GPR35/CXCR8 agonist.Formula:C10H7NO3Purity:99.69%Color and Shape:SolidMolecular weight:189.17PU-H54
CAS:PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.Formula:C18H19N5SPurity:99.13%Color and Shape:SolidMolecular weight:337.44
