Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
Products of "Glucocorticoid Receptor"
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Medrysone
CAS:Medrysone is a synthetic glucocorticoid for topical use with anti-inflammatory and anti-allergic effects, altering gene expression to reduce inflammation.Formula:C22H32O3Purity:97.72% - 99.91%Color and Shape:SolidMolecular weight:344.49Prednisolone hemisuccinate
CAS:Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.Formula:C25H32O8Purity:99.96%Color and Shape:SolidMolecular weight:460.52Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formula:C24H31FO6Purity:99.22% - 99.65%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:434.5GSK9027
CAS:GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.Formula:C27H19F4N3O2SPurity:99.36%Color and Shape:SolidMolecular weight:525.52N-Demethyl Mifepristone
CAS:N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone'Formula:C28H33NO2Purity:98%Color and Shape:SolidMolecular weight:415.57Apararenone
CAS:Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.Formula:C17H17FN2O4SPurity:99.65%Color and Shape:SolidMolecular weight:364.3922-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Color and Shape:SolidMolecular weight:445.59Prednisolone acetate
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C23H30O6Purity:98.26% - 98.85%Color and Shape:White Crystalline PowderMolecular weight:402.48Fluticasone furoate
CAS:Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.Formula:C27H29F3O6SPurity:99.58%Color and Shape:SolidMolecular weight:538.58Ref: TM-T21404
4g2,663.00€5mg35.00€10mg52.00€25mg92.00€50mg137.00€100mg187.00€200mg279.00€500mg472.00€1mL*10mM (DMSO)58.00€Mifepristone
CAS:Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.Formula:C29H35NO2Purity:98.9% - ≥95%Color and Shape:Pale Yellow SolidMolecular weight:429.59Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formula:C24H30F2O6Purity:99.29% - 99.66%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49Miricorilant
CAS:Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic disorders.Formula:C24H23F3N2O2Purity:98.62%Color and Shape:SolidMolecular weight:428.45Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purity:96.92% - 98.03%Color and Shape:Crystalline SolidMolecular weight:422.49Dexamethasone palmitate
CAS:DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Formula:C38H59FO6Purity:98.08%Color and Shape:SolidMolecular weight:630.87Triamcinolone hexacetonide
CAS:Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.Formula:C30H41FO7Purity:99.57%Color and Shape:SolidMolecular weight:532.64Amcinonide
CAS:Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.Formula:C28H35FO7Purity:98.33% - 99.62%Color and Shape:SolidMolecular weight:502.57Budesonide
CAS:Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects against multiple cells types and mediators referred to allergic and nonallergic-mediated inflammatory. What's more, the anti-inflammatory action of budesonide has been revealed to contribute to the effectiveness of asthma.Formula:C25H34O6Purity:99.03% - 99.72%Color and Shape:Crystals SolidMolecular weight:430.53Cortisone acetate
CAS:Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory andFormula:C23H30O6Purity:98.63% - 99.73%Color and Shape:SolidMolecular weight:402.48Corticosterone
CAS:Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.Formula:C21H30O4Purity:97.25% - ≥95%Color and Shape:SolidMolecular weight:346.46Prednisolone
CAS:Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C21H28O5Purity:99.59% - 99.85%Color and Shape:Crystals SolidMolecular weight:360.44(20S)-Protopanaxatriol
CAS:(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoidFormula:C30H52O4Purity:95% - 99%Color and Shape:SolidMolecular weight:476.73Glucocorticoid receptor agonist-5
CAS:Glucocorticoid Receptoragonist-5 (compound 4) is an effective glucocorticoid molecule acting as a potent agonist for glucocorticoid receptors. It exhibits anti-inflammatory and immunosuppressive activities and serves as an ADC cytotoxin.Formula:C36H40O7Color and Shape:SolidMolecular weight:584.7Triamcinolone acetonide
CAS:Triamcinolone acetonide (Azmacort) is a Corticosteroid.Formula:C24H31FO6Purity:99.61% - 99.91%Color and Shape:White To Off-White Crystalline PowderMolecular weight:434.5Triamcinolone
CAS:Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C21H27FO6Purity:98.59% - 99.60%Color and Shape:SolidMolecular weight:394.43Hydrocortisone aceponate
CAS:Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid used in the form of a cream to treat various skinFormula:C26H36O7Purity:99.53%Color and Shape:SolidMolecular weight:460.56Glucocorticoid receptor agonist-1
CAS:Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].Formula:C35H39NO6Purity:99.51%Color and Shape:SolidMolecular weight:569.69Ref: TM-T37908
1mg87.00€5mg172.00€10mg279.00€25mg553.00€50mg885.00€100mg1,415.00€200mg1,872.00€1mL*10mM (DMSO)217.00€Mirodenafil dihydrochloride
CAS:Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H39Cl2N5O5SPurity:99.64% - 99.78%Color and Shape:SolidMolecular weight:604.59LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Formula:C7H9NO6SPurity:99% - 99.16%Color and Shape:SolidMolecular weight:235.22AL 082D06
CAS:AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR.Formula:C23H24ClN3O2Purity:99.05% - 99.06%Color and Shape:SolidMolecular weight:409.91Desonide
CAS:Desonide is a synthetic topical steroid that reduces inflammation by inhibiting key inflammatory mediators.Formula:C24H32O6Purity:99.29% - 99.5%Color and Shape:SolidMolecular weight:416.51Methylprednisolone succinate
CAS:Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.Formula:C26H34O8Purity:98.41% - 99.82%Color and Shape:White Or Almost-White Solid PowderMolecular weight:474.54Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purity:98% - 99.91%Color and Shape:Crystals From Ether (Ntp 1992)Molecular weight:392.46EX-A5386
CAS:EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.Formula:C29H27FN4O2Purity:99.69%Color and Shape:SoildMolecular weight:482.55Esaxerenone
CAS:Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.Formula:C22H21F3N2O4SPurity:99.68%Color and Shape:SolidMolecular weight:466.47Ref: TM-T15246
1mg70.00€5mg144.00€10mg227.00€25mg439.00€50mg702.00€100mg1,103.00€500mg2,205.00€1mL*10mM (DMSO)159.00€Canrenoate potassium
CAS:Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.Formula:C22H29KO4Purity:99.04% - 99.18%Color and Shape:Light Yellow To Tan PowderMolecular weight:396.56Desisobutyryl-ciclesonide
CAS:Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide with affinity for the glucocorticoid receptor. a glucocorticoid with anti-inflammatory.Formula:C28H38O6Purity:98%Color and Shape:SolidMolecular weight:470.6Beclometasone
CAS:Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.Formula:C22H29ClO5Purity:99.41% - 99.68%Color and Shape:White To Off-White Crystalline PowderMolecular weight:408.92NR3C1 Protein, Human, Recombinant (His)
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene.Color and Shape:Lyophilized PowderMolecular weight:10.95 kDa (predicted)Cort108297
CAS:Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Formula:C26H25F4N3O3SPurity:100% - 98%Color and Shape:SolidMolecular weight:535.55Ref: TM-T15000
1mg274.00€5mg622.00€10mg908.00€25mg1,415.00€50mg1,882.00€100mg2,745.00€1mL*10mM (DMSO)747.00€Prednisolone valerate acetate
CAS:Prednisolone valerate acetate is a prodrug anti-inflammatory and immunosuppressive,converted to the active form of Prednisolone and glucocorticoid receptor.Formula:C28H38O7Purity:99.93%Color and Shape:SolidMolecular weight:486.6Halcinonide
CAS:Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.Formula:C24H32ClFO5Purity:99.32% - 99.93%Color and Shape:SolidMolecular weight:454.96Ref: TM-T0107
1g567.00€10mg48.00€25mg65.00€50mg81.00€100mg131.00€200mg205.00€500mg373.00€1mL*10mM (DMSO)44.00€Fluorometholone
CAS:Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery.Formula:C22H29FO4Purity:98.21%Color and Shape:SolidMolecular weight:376.46Megestrol acetate
CAS:Megestrol acetate (BDH1298) is an oral progestogen with anti-androgenic properties, used for endometrial and breast cancer, anorexia, and cachexia.Formula:C24H32O4Purity:99.46%Color and Shape:Crystalline SolidMolecular weight:384.51Hydrocortisone
CAS:Hydrocortisone is a synthetic glucocorticoid that aids in metabolism, immunity, and inflammation control.Formula:C21H30O5Purity:98.4% - 99.95%Color and Shape:Plates From Alc Or Iso-Propyl Alc SolidMolecular weight:362.46Eplerenone
CAS:Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension.Formula:C24H30O6Purity:99.75% - ≥98%Color and Shape:White SolidMolecular weight:414.49Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Formula:C22H28O4Purity:99.54%Color and Shape:SolidMolecular weight:356.46Ref: TM-T17217
1mg37.00€2mg52.00€5mg79.00€10mg111.00€25mg188.00€50mg298.00€100mg444.00€200mg640.00€1mL*10mM (DMSO)87.00€Osilodrostat
CAS:Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2).Cost-effective and quality-assured.Formula:C13H10FN3Purity:99.10% - 99.31%Color and Shape:SolidMolecular weight:227.24Clobetasol propionate
CAS:Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediatedFormula:C25H32ClFO5Purity:99.41%Color and Shape:White Crystalline PowderMolecular weight:466.97Mometasone furoate
CAS:Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA andFormula:C27H30Cl2O6Purity:99.43% - 99.48%Color and Shape:Distributed As 0 1% Ointment With A Petrolatum BaseMolecular weight:521.43Fluocinonide
CAS:Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.Formula:C26H32F2O7Purity:100% - 99.70%Color and Shape:SolidMolecular weight:494.52
