Androgen Receptor
The androgen receptor (AR) is a nuclear hormone receptor that is activated by binding to androgens, such as testosterone and dihydrotestosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, as well as in the regulation of several physiological processes, including muscle growth, libido, and bone density. Androgen receptor inhibitors are widely studied in the context of prostate cancer, where AR signaling is often upregulated. At CymitQuimica, we offer a range of high-quality androgen receptor modulators to support your research in endocrinology, cancer biology, and hormone regulation.
Products of "Androgen Receptor"
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AR antagonist 10
CAS:AR antagonist 10 (Compound Y5) is a potent, orally active androgen receptor (AR) antagonist with an IC50 value of 0.04 μM. It demonstrates a dual mechanism of action: antagonizing AR by disrupting AR dimerization and inducing AR degradation through the ubiquitin-proteasome pathway. This compound shows excellent activity against various resistant AR mutants and effectively inhibits the growth of LNCaP xenograft tumors. AR antagonist 10 is applicable for research in resistant prostate cancer.Formula:C18H17ClN4O3SColor and Shape:SolidMolecular weight:404.871Dehydroisoandrosterone 3-acetate
CAS:Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.Formula:C21H30O3Purity:100% - 99.81%Color and Shape:SolidMolecular weight:330.46ONC1-13B
CAS:ONC1-13B, an androgen receptor antagonist, is used potentially for the treatment of prostate cancer.Formula:C22H16F4N4O3SPurity:99.45% - 99.85%Color and Shape:SolidMolecular weight:492.45ARD-2585
CAS:ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.Formula:C41H43ClN8O5Color and Shape:SolidMolecular weight:763.28LY2452473
CAS:LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.Formula:C22H22N4O2Purity:99.72%Color and Shape:SolidMolecular weight:374.44Ref: TM-T15804
1mg35.00€5mg74.00€10mg97.00€25mg149.00€50mg188.00€100mg281.00€200mg429.00€1mL*10mM (DMSO)81.00€p,p'-DDE
CAS:p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDTFormula:C14H8Cl4Purity:99.68%Color and Shape:White Crystalline Solid Physical Description White Crystalline Solid Or White Powder (Ntp 1992)Molecular weight:318.03Androgen receptor antagonist 12
CAS:Compound EF2 (Androgen receptor antagonist 12) is an orally active antagonist of the androgen receptor (AR) with an IC50 of 0.30 µM. It inhibits the transcriptional activity of mutant AR and the proliferation of AR-positive PCa (prostate cancer) cell lines. Additionally, Compound EF2 blocks the nuclear translocation of AR and suppresses tumor growth in the C4-2B xenograft mouse model. This compound is used for research in prostate cancer.Formula:C12H8F3N3O2Color and Shape:SolidMolecular weight:283.21LX1
CAS:LX1, an anti-prostate cancer compound, specifically targets the androgen receptor (AR), AR variants, and the steroidogenic enzyme AKR1C3. It inhibits AKR1C3's enzymatic function, decreases the conversion of androstenedione to testosterone, and reduces the expression of both AR and AR-V7, subsequently downregulating their target genes. Additionally, LX1 is effective in overcoming tumor cell resistance to Enzalutamide, and when combined with Enzalutamide, it further suppresses tumor growth.Formula:C22H15F6NO2Color and Shape:SolidMolecular weight:439.35CTK8A3536
CAS:CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.Formula:C14H16N2O2SPurity:99.62%Color and Shape:SolidMolecular weight:276.35Ref: TM-T8592
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)169.00€Pentomone
CAS:Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.Formula:C24H26O5Color and Shape:SolidMolecular weight:394.46Zanoterone
CAS:Zanoterone is an AR antagonist (androgen receptor).Zanoterone has antitumor activity for the treatment of genitourinary disorders and oncological disorders andFormula:C23H32N2O3SPurity:99.85% - 99.96%Color and Shape:SoildMolecular weight:416.58Bavdegalutamide
CAS:Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR).Formula:C41H43ClFN9O6Purity:97.17% - 99.04%Color and Shape:SolidMolecular weight:812.29ARD-2128
CAS:ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.Formula:C45H50ClN7O6Purity:98.80%Color and Shape:SolidMolecular weight:820.37Bifluranol
CAS:Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostaticFormula:C17H18F2O2Purity:99.77%Color and Shape:SolidMolecular weight:292.32Gridegalutamide
CAS:Gridegalutamide exhibits anti-androgen and anti-tumor activities.Formula:C41H45F3N8O5SColor and Shape:SolidMolecular weight:818.91Vosilasarm
CAS:RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.Formula:C20H16ClN5O2Purity:99.01% - 99.6%Color and Shape:A Crystalline SolidMolecular weight:393.82(+)-JJ-74-138
CAS:(+)-JJ-74-138 is a novel non-competitive androgen receptor (AR) antagonist capable of inhibiting enzalutamide-resistant castration-resistant prostate cancer (CRPC).Formula:C22H22F8N2OSColor and Shape:SolidMolecular weight:514.48YXG-158
CAS:YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1Formula:C30H36FN3OPurity:98%Color and Shape:SolidMolecular weight:473.62ACP-105
CAS:ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgenFormula:C16H19ClN2OPurity:99.53%Color and Shape:SolidMolecular weight:290.79Ref: TM-T14116
2mg38.00€5mg58.00€10mg90.00€25mg164.00€50mg226.00€100mg325.00€200mg455.00€1mL*10mM (DMSO)65.00€MI-136
CAS:MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formula:C23H21F3N6SPurity:97.08% - 98.63%Color and Shape:SolidMolecular weight:470.51Ref: TM-T6889
1mg47.00€5mg87.00€10mg147.00€25mg279.00€50mg472.00€100mg730.00€200mg1,017.00€1mL*10mM (DMSO)97.00€BMS-641988
CAS:BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.Formula:C20H20F3N3O5SPurity:100% - 100%Color and Shape:SoildMolecular weight:471.45N-desmethyl Enzalutamide
CAS:N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.Formula:C20H14F4N4O2SPurity:99.74%Color and Shape:SolidMolecular weight:450.41Ref: TM-T19450
2mg34.00€5mg52.00€10mg74.00€25mg138.00€50mg255.00€100mg375.00€200mg532.00€1mL*10mM (DMSO)58.00€Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurity:100% - 99.7%Color and Shape:SolidMolecular weight:464.44Ref: TM-T6002
5mg48.00€10mg56.00€25mg74.00€50mg96.00€100mg154.00€200mg187.00€500mg274.00€1mL*10mM (DMSO)52.00€Triptophenolide
CAS:Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.Formula:C20H24O3Purity:98.07% - ≥95%Color and Shape:White PowderMolecular weight:312.4Anti-Androgen receptor Antibody (7Q574)
Anti-Androgen receptor Antibody (7Q574) is an antibody targeting Androgen receptor. Anti-Androgen receptor Antibody (7Q574) can be used in ELISA, WB, IHC.Color and Shape:Odour LiquidGLPG0492
CAS:GLPG0492 is a novel selective androgen receptor modulator.Formula:C19H14F3N3O3Purity:98.27%Color and Shape:SolidMolecular weight:389.33Ref: TM-T11410L
1mg74.00€5mg164.00€10mg235.00€25mg378.00€50mg543.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)170.00€Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Formula:C29H25F4N5O2Color and Shape:SolidMolecular weight:551.53GDC-2992
CAS:GDC-2992 is a selective and oral AR (androgen receptor) degrader that, degrades AR and inhibits proliferation in VCaP cells, prostate cancer (CRPC).Formula:C45H51ClN8O5Color and Shape:SoildMolecular weight:819.39Androgen receptor degrader-2
CAS:Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].Formula:C16H16ClN3O4Purity:98%Color and Shape:SolidMolecular weight:349.77UT-34
CAS:UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wildFormula:C15H12F4N4O2Purity:98.12%Color and Shape:SolidMolecular weight:356.27Ref: TM-T13273
1mg52.00€5mg119.00€10mg187.00€25mg354.00€50mg533.00€100mg825.00€1mL*10mM (DMSO)131.00€Ailanthone
CAS:Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated ARFormula:C20H24O7Purity:99.71% - 99.96%Color and Shape:SolidMolecular weight:376.4ARD-266
CAS:ARD-266 is a PROTAC degrader based on the von Hippel-Lindau E3 ligase that induces the degradation of AR proteins and is useful in prostate cancer research.Formula:C52H59ClN6O7Purity:99.89%Color and Shape:SolidMolecular weight:915.51Andarine
CAS:Andarine (GTx-007) (S-4) is an active partial agonist and an investigational selective androgen receptor modulator (SARM).Formula:C19H18F3N3O6Purity:99.84%Color and Shape:Pale Yellow SolidMolecular weight:441.36DSRM-3716
CAS:Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery ofFormula:C9H6INPurity:99.74%Color and Shape:SolidMolecular weight:255.063,3'-Diindolylmethane
CAS:3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Formula:C17H14N2Purity:100%Color and Shape:SolidMolecular weight:246.31Ligandrol
CAS:Ligandrol is a novel nonsteroidal, oral SARM that binds to the androgen receptor with high affinity (Ki: 1 nM) and selectivity.Formula:C14H12F6N2OPurity:100%Color and Shape:SolidMolecular weight:338.25Masofaniten
CAS:Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.Formula:C24H24Cl2N4O4SPurity:98.42% - 98.66%Color and Shape:SolidMolecular weight:535.44Nilutamide
CAS:Nilutamide, a nonsteroidal anti-androgen, treats prostate cancer by blocking androgen receptors, not affecting other hormone receptors.Formula:C12H10F3N3O4Purity:98.45% - 98.67%Color and Shape:Crystalline SolidMolecular weight:317.22Enzalutamide carboxylic acid
CAS:Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .Formula:C20H13F4N3O3SPurity:97.88%Color and Shape:SolidMolecular weight:451.39Ref: TM-T8217
1mg66.00€2mg93.00€5mg126.00€10mg187.00€25mg315.00€50mg439.00€100mg648.00€1mL*10mM (DMSO)140.00€Androgen receptor-IN-5
CAS:Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties.Formula:C22H10Cl2F4N4OSPurity:98%Color and Shape:SolidMolecular weight:525.31EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formula:C21H27ClO5Purity:99% - 99.28%Color and Shape:SolidMolecular weight:394.89Ref: TM-T6829
2mg35.00€5mg50.00€10mg77.00€25mg127.00€50mg202.00€100mg303.00€200mg449.00€1mL*10mM (DMSO)51.00€RU 58841
CAS:RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen; RU 58841(PSK-3841) has a significant effect on hair regrowth.Formula:C17H18F3N3O3Purity:99.31% - 99.70%Color and Shape:SolidMolecular weight:369.34Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57Dimethylcurcumin
CAS:Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer.Formula:C23H24O6Purity:97.36% - 98.96%Color and Shape:SolidMolecular weight:396.432,2,5,7,8-Pentamethyl-6-Chromanol
CAS:2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation andFormula:C14H20O2Purity:98.72%Color and Shape:SolidMolecular weight:220.31VPC-13566
CAS:VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from theFormula:C18H14N2Purity:99.37%Color and Shape:SolidMolecular weight:258.32Ref: TM-T29111
1mg48.00€2mg65.00€5mg97.00€10mg160.00€25mg329.00€50mg540.00€100mg847.00€500mg1,730.00€1mL*10mM (DMSO)114.00€Rezvilutamide
CAS:Rezvilutamide (SHR3680) is an orally available androgen receptor inhibitor that crosses the blood-brain barrier and has antitumor activity.Formula:C22H20F3N3O4SPurity:99.97%Color and Shape:SolidMolecular weight:479.47ARD-1676
CAS:ARD-1676 is an orally administered androgen receptor (AR) PROTAC degrader that combines an AR ligand with a cereblon ligand.Formula:C44H46ClN7O5Purity:98%Color and Shape:SolidMolecular weight:788.33AC-262536
CAS:AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor.Formula:C18H18N2OPurity:99.38%Color and Shape:SolidMolecular weight:278.35Ref: TM-T26539
5mg46.00€10mg74.00€25mg145.00€50mg240.00€100mg359.00€200mg510.00€1mL*10mM (DMSO)49.00€Boldenone Undecylenate
CAS:Boldenone Undecylenate (Parenabol) is a synthetic steroid.Formula:C30H44O3Purity:99.39%Color and Shape:Light Yellow Oily MatterMolecular weight:452.67Ref: TM-T3137
1mg35.00€2mg48.00€5mg52.00€10mg85.00€25mg140.00€50mg246.00€100mg396.00€500mg939.00€1mL*10mM (DMSO)52.00€
