Enzyme

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

PTGES3 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.

α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.

Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family.

AMPK (G1/B1/A2) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Catalyzes the reverse reaction of octopine dehydrogenation.

HAAO Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Lipase 70 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 35-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 70 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (62 %), laurate (15 %), palmitate (4 %), stearate (3 %), arachidate (2 %) and behenate (0.2 %).

Ribonuclease H1 Protein, Human, Recombinant (His) is expressed in E. coli.

Creatine kinase M/CKM Protein, Human, Recombinant is expressed in E. coli.

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Essential for bone resorption and osteoclast differentiation.

Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which

The main protease Mpro is a key protein in the lifecycle of the SARS-CoV-2 virus. Mpro cleaves the viral polyproteins at the C-terminal end of a glutamine residue in recognition sequences containing Leu-Gln-(Ser, Ala, Gly) motifs (Rut et al, 2020).  As SARS-CoV-2 MPro has no closely related homologues in humans, it represents an attractive drug target (Ullrich and Nitsche, 2020). In summary, the Mpro protease is a chymotrypsin-like cysteine protease, requires homodimerisation for proteolytic activity, cleaves the viral polyproteins in 11 distinct sites, exclusively after a glutamine residue. A fluorogenic substrate for Mpro assays is Ac-Abu-Tle-Leu-Gln-AMC.The protein amount or better its concentration in solution is quantified using either A280 (absorption at 280 nm with its specific absorption coefficient) or using the Bradford assay (uses the dye Coomassie Brilliant Blue). Both of these methods quantify the total amount of protein in a sample, no matter what the oligomerization state is.

Beta-D-glucuronidase from E.coli is a  highly specific enzyme in hydrolyzing glucuronides.

LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E.

SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E.

Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to

Plays a key role in glycolysis and gluconeogenesis.

Catalyzes the oxidation of methanol to yield formaldehyde.

ENTPD3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Triose-phosphate isomerase (TPI, TIM; EC 5.3.1.1) is an enzyme that catalyzes the reversible isomerisation of dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate:  DHAP ⇌ GADP  The reaction mechanism involves the formation of an enediol intermediate. One unit of Triose-phosphate isomerase will convert 1.0 μmole glyceraldehyde 3-phosphate to dihydroxyacetone phosphate per min at pH 7.6 and 25 °C.

Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.

RIZ1 Protein, Human, Recombinant (GST) is expressed in E.

Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space.

2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is an isomer of Vanillin, and a potent tyrosinase inhibitor, could be used to synthesis Urolithin M7.

In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.

Exostosin-like 2 (EXTL2) is a member of the exostosin (EXT)-related family which contains five members: EXT1, EXT2, EXTL1, EXTL2, and EXTL3.

α-Glucosidase (EC 3.2.1.20) is a glycoside hydrolase enzyme that hydrolyzes α-1,4-linked D-glucose residues (e.g. in starch or oligosaccharides)  to produce α-D-glucose. One unit of α-Glucosidase will release 1.0 µmole of p-nitrophenol from the chromogenic substrate mimic 4-nitrophenyl α-D-glucopyranoside per minute at pH 6.8 and 37 °C.

A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis.

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.

Creatinase (EC 3.5.3.3) is an enzyme that catalyzes the fellowing reaction: creatine + H2O ⇌ sarcosine + ureaOne unit of creatinase will hydrolyze 1.0 µmole of creatine into sarcosine and urea per min at pH 7.5 and 37 °C.

ABHD11 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q8NFV4.

Lyn Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

DDR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q16832.

Alteplase is human plasminogen activator (EC 3.4.21.68, that cleaves plasminogen into enzymatically active form, plasmin), recombinantly expressed in CHO cells. Alteplase belongs to the group of thrombolytic agents, and it has shown to be effective in restoring blood flow by breaking down clots.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Critical role in recombination and DNA repair.

MAST4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis.

ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

LRRK2 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q5S007.

Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family.

Ultra nuclease (EC 3.1.30.2) is an enzyme that digests DNA and RNA in any form: single- and double-stranded, linear, circular and supercoiled. The ultimate reaction product is 5'-monophosphate oligonucleatides that are mostly three, four and five bases long. Please enquire for more information about Ultra nuclease, liquid, recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page

PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.

Chymotrypsinogen B (CTRB1) is a 263 amino acid protein with signal peptide (1-18) and Chymotrypsinogen B (19-263).

Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

Beta-Tocopherol has effects on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).Cost-effective and quality-assured.

HDAC8 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and

Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin.

The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine

Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis.

Streptodornase is a DNase that is often present as in the streptokinase preparations as an impurity.

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ACOD1 Protein, Human, Recombinant (His) is expressed in E.

Protease whose physiological substrate is not yet known.

Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway.

B3GNT6 belongs to the glycosyltransferase 31 family.

Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family.

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of

Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].

CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism.

Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family.

Amidase (EC 3.5.1.4) is a hydrolase acting on carbon-nitrogen bonds in linear amides and can be used in the hydrolysis of amides to acids. Amidase 02 is of bacterial origin (R. erythropolis and has been produced in E.coli).

Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and

Spermine Oxidase Protein, Mouse, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q99K82.

NUDT2 Protein, Human, Recombinant (His) is expressed in E.

Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states.

Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens.

L-Glutamate oxidase is a deaminating oxidoreductase that catalyzes the conversion of L-glutamate to ketoglutarate, ammonia and hydrogen peroxide. The enzyme has been shown to have significant potential for immobilization on an insoluble support such as silica gel, which would allow it to be used in assays requiring higher concentrations of substrate. This property is important for industrial applications such as biosensor development for clinical biochemistry and the food industry. Unit definition: One unit will form 1.0 micromole of alpha-ketoglutaric acid from L-glutamic acid per minute at pH 7.4 at 30 deg C.

CSNK1E Protein, Human, Recombinant (His) is expressed in E.

Catalyzes the hydrolysis of levan with endo-type specificity.

Active on elastin and collagen substrates.

Nitrile hydratase 10 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amides, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.

ErbB4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family.

CYP11A1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated is expressed in E. coli with N-MBP, C-6xHis-Avi. The accession number is Q9QZ82.

VNN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Myokinase (Adenylate kinase, EC 2.7.4.3) catalyzes interconversion between ATP, ADP and AMP by catalyzing the following reaction:ATP + AMP ⇌ 2 ADPOne unit of Myokinase will convert 1.0 µmol ATP and 1.0 µmol AMP to 2.0 µmol ADP per min at 25°C and pH 7.5.

Reversible hydration of carbon dioxide.

Carbohydrate deacetylase Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is A8MPS7.

MUSK Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.8 kDa and the accession number is O15146.

Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily.

Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E.

Regulates the level of the neuromodulator D-serine in the brain.

Glucosyltransferases (GTases) can be utilized as enzymes to transfer glucose to another organic molecule (aglycon) establishing glycosidic linkages. UDP-glucose dependent GTases are part of the enzyme family of glycosyltransferases, they are versatile tools in glucosylation reactions. Our kit contains 8 lyophilized enzymes, which cover a wide range of different aglycons for the synthesis of glucosides: aliphatic, terpene, aromatic and heterocyclic glucosides.Overall the process of glycosylation is highly beneficial to both the pharma and cosmetic industries. Particularly the ability of GTases to transfer glucose to organic molecules (aglycon), is a sought-after activity for water-soluble formulations in the cosmetic industry. This is because the addition of a sugar moiety can result in a more hydrophilic product. Not only this but glucosyltransferase can be utilized to synthesize aliphatic, terpene, aromatic and heterocyclic glucosides, used in flavour or fragrance applications. In the pharma industry, glycosylating active pharmaceutical ingredients can improve the solubility of active ingredients, allowing the possibility for patient to take medication in a liquid form. This would be more accessible to those patients who find taking tablets difficult.Contact our enzyme experts for custom glucoside synthesis services, based on our full library of glycosyltransferases.

DT3C Protein, Recombinant (His) is expressed in E. coli.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

METTL11A Protein, Human, Recombinant (GST) is expressed in E.