Enzyme

Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Sialidase-3 Protein, Human, Recombinant (His) is expressed in E.

mTOR Protein, Human, Recombinant (His & Myc) is expressed in E.

Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.

This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.

DNM1L Protein, Human, Recombinant (His & Myc) is expressed in E.

D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family.

Creatinase is an enzyme (EC 3.5.3.3) that catalyzes the conversion of creatine to sarcosine and urea.

Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Enzyme involved in the reduction of hydrogen peroxide to water and oxygen. This is a highly important reaction as it protects the cell from oxidative damage.

Protein transport.

Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside).

Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid.

Carboxypeptidase A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PDP2 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q9P2J9.

Cyclophilin A Protein, Mouse, Recombinant (His) is expressed in E.

E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

NT5C1A Protein, Human, Recombinant (His) is expressed in Yeast.

Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.

AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .

PDK3 Protein, Mouse, Recombinant (His) is expressed in E.

Caspase 14 is a member of the caspase family.

Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway.

Involved in the maturation of Asn-linked oligosaccharides.

Intercellular signal essential for a variety of patterning events during development.

N/A.

Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with

PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated

PCSK9 Protein, Human, Recombinant (D374Y, His) is expressed in HEK293 mammalian cells with His tag.

Protein phosphatase 2C is a key enzyme, which is a serine/threonine-specific phosphatase, derived from various organisms including humans, plants, and bacteria. This enzyme plays a pivotal role in cellular signaling by removing phosphate groups from serine and threonine residues on target proteins, a process known as dephosphorylation. This action is crucial for the regulation of diverse cellular functions, including stress responses, cell division, and apoptosis. Protein phosphatase 2C is widely studied for its involvement in modulating cellular responses to environmental stresses and its role in various signaling pathways. By maintaining the balance between phosphorylation and dephosphorylation, the enzyme ensures proper signal transduction and cellular homeostasis. Researchers extensively investigate its function to understand cellular processes better and to explore therapeutic targets for diseases where signaling pathways are disrupted. Its applications extend to fields such as cancer research, neurobiology, and the study of metabolic disorders, among others. Understanding the intricacies of this enzyme opens doors to potential advancements in therapeutic strategies and the broader comprehension of cellular biology.

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity

KAT5 Protein, Human, Recombinant (His) is expressed in E. coli.

Urate Oxidase, also known as uricase, catalizes the following reaction: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2.

Specific activity: >500 units/mg-protein.Unit definition: One unit will polymerize 1.0 micro mole of ADP, releasing 1.0 micro mole of inorganic phosphate in 15 minutes at pH 9.1 at 37 °C.

PML Protein, Human, Recombinant (His) is expressed in E.

DCP2 Protein, Human, Recombinant (His) is expressed in E.

L-Leucine dehydrogenase (Leucine dehydrogenase, systematic name L-leucine:NAD+ oxidoreductase (deaminating); EC 1.4.1.9) is an enzyme that catalyzes the following reaction:  L-leucine + H2O + NAD+ ⇌ 4-methyl-2-oxopentanoate + NH3 + NADH + H+  One unit of L-Leucine dehydrogenase will convert 1.0 µmole of L-leucine into 4-methyl-2-oxopentanoate per min at pH 10.5 and 37 °C in the presence of NAD+. The enzyme requires NAD+ as a cofactor, it is available here.

CRELD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Cell wall formation.

ST8SIA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324

Essential virulence determinant.

Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues,

Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density

Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates.

Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

DNASE1L3 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-10xHis. The accession number is O55070.

Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and

Endothelin-converting enzyme 1, also known as ECE-1, is a single-pass type II membrane protein which belongs to thepeptidase M13 family.

AKT2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q60823.

May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition.

HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

IscS Protein, E.

Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.

Aminoacylase 1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

P4HB Protein, Cricetulus griseus, Recombinant (His) is expressed in Yeast.

Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family.

N/A.

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.

Glutamic pyruvic transaminase (also Alanine transaminase, alanine aminotransferase; E.C. 2.6.1.2) is an enzyme that catalyzes the following reaction:  L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate  One unit of Glutamic pyruvic transaminase will catalyze the conversion of 1.0 µmole per minute of L-alanine and α-ketoglutarate to L-glutamate and pyruvate, at 37°C and pH 7.4.

E3 SUMO protein ligase involved in regulation processes.

Catalyzes the oxidation of methanol to yield formaldehyde.

Cathepsin L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

5′-Nucleotidase (EC 3.1.3.5) is an enzyme that catalyzes hydrolysis of 5' nucleotides, removing the phosphate group:  AMP + H2O ⇌ adenosine + Pi  One unit of 5′-Nucleotidase will generate 1.0 μmole of phosphate ions per minute in the presence of AMP under optimal reaction conditions.

Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family.

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

SEPHS2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of

VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

BoNT/A Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.

SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.

CDK7 & CCNH & MNAT1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that

Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to

Creatine kinase B/CKB Protein, Human, Recombinant is expressed in E. coli.

72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs

CSK Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

PDIA3 protein is also known as Protein disulfide-isomerase A3.

Serine hydrolase whose substrates have not been identified yet.

Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family.

Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.

Cysteine proteinase with a strong preference for substrates with Lys in the P1 position.

Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and

CPQ may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor._x000D_ Carboxypeptidase Q Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.72 kDa and the accession number is Q9Y646.

Carbonic Anhydrase 14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N/A.

Caspase-8 Protein, Human, Recombinant (His) is expressed in E.

Possesses thioredoxin activity.

hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.

hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.

Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate

PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion.

ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag.

RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase.

Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine to hydrogen sulfide and other thiol compounds including

PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1.

Potassium iodide 用于治疗过度活跃的甲状腺,并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。

Trypsin (EC 3.4.21.4) is a protease that hydrolyses proteins by cleaving the peptide bond at the carboxyl side of the positively charged amino acid (Lysine or Arginine). Trypsin belongs to a family of serine proteases, as it has a serine in its active site. Trypsin can be inhibited by using trypsin inhibitor Alpha 1 Antitrypsin.

Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting

Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) belongs to the ubiquitin-conjugating enzyme family.

Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO) is expressed in E.

Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.

DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

Glucosyltransferase (GTase) is the enzyme that transfers glucose to another organic molecule (aglycon), establishing glycosidic linkage. UDP-glucose dependent GTases are part of the enzyme family of glucosyltransferases, they are versatile tools in glucosylation reactions. Different GTases have different substrate specificities. For the specificity of GT205 Glucosyltransferase, please see Table 1 that lists the available GTases with GT205 highlighted.Color: beigeForm: lyophilisateProtein content: 0.5 mg/mgThe glucosyltransferase was tested in a glucosylation reaction of a preferred substrate. High conversion after up to 24 hr reaction time was observed. Not sure which GTase to choose? Consider our Glucosyltransferase kit, which contains all 8 Glucosyltransferases.

Adenylate kinase 1 (EC 2.7.4.3) catalyzes interconversion between ATP, ADP and AMP by catalyzing the following reaction:  ATP + AMP ⇔ 2 ADP  One unit of Adenylate kinase 1 will convert 1.0 µmol ATP and 1.0 µmol AMP to 2.0 µmol ADP per min at optimum conditions.