Enzyme

Superoxide dismutase is an enzyme that catalyzes the conversion of harmful superoxide into hydrogen peroxide and oxygen.

Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family.

CDK7 Protein, Human, Recombinant is expressed in E. coli.

TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring

Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing

Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and

Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin.

CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic

Cathepsin E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic

Serine palmitoyltransferase (SPT).

Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor.

May be involved in cell growth.

DNase I (Deoxyribonuclease I, EC 3.1.21.1) is an endonuclease that cleaves DNA, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3'. On average it produces tetranucleotides. One unit of the DNase I will increase the absorbance of 260nm light at a rate of 0.001/minute in 1 ml reaction volume at 25°C.

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Adenosine kinase(ADK) belongs to the family of transferases.

Lipase 13 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 35-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 13 was shown to hydrolyze p-Nitrophenyl esters of butyrate (87 % activity compared to octanoate), octanoate (100 %), palmitate (44 %), stearate (21 %) and arachidate (2 %).

PLA2G1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

GPX1 Protein, Human, Recombinant (U49S, His) is expressed in E. coli with N-6xHis. The accession number is P07203.

Aldolase C Protein, Mouse, Recombinant (His & Myc) is expressed in E.

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the

Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.

CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.

Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Responsible for the biosynthesis of pyroglutamyl peptides.

ABCD1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.

Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.

N/A.

ACACA Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q13085.

Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.

Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

BLM Protein, Mouse, Recombinant (His & Myc) is expressed in E.

UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene.

Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.

P4HA3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which

Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II.

PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle.

Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific

MMP-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PADI2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.

PADI2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

Lipase 06 recombinantly expressed in E. coli comes in a freeze-dried formulation. It has its pH optimum at 7 and temp. optimum at 30-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 06 was shown to hydrolyze p-Nitrophenyl esters of butyrate (91 % activity compared to octanoate), octanoate (100 %), laurate (13 %), palmitate (1 %), stearate (2 %), arachidate (0.3 %) and behenate (1 %).

NEIL1 is a member of DNA glycosylases.

RIOK3 Protein, Human, Recombinant (E.

Has a strict specificity for hydrolysis of asparaginyl bonds.

SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine

Cathepsin A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of

Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.

GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair.

MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells.

ATP5D is a subunit of mitochondrial ATP synthase.

NCEH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q6PIU2.

8-oxo-dGTP diphosphatase Protein, E.

CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Endopeptidase, powder, is a proteolytic enzyme, which is typically derived from microbial, plant, or animal sources, each imparting unique specificities. This enzyme functions by cleaving peptide bonds within polypeptide chains, rather than terminal bonds, thereby facilitating the breakdown of proteins into smaller, more manageable peptide fragments. The mode of action involves recognizing specific amino acid sequences within the substrate, leading to targeted bond hydrolysis. Endopeptidases have wide-ranging applications in both industrial and research settings. In the laboratory, they are instrumental in protein digestion and analysis, aiding in structure-function studies, as well as in preparing proteins for mass spectrometry. In biotechnology and bioprocessing, these enzymes are utilized to modify proteins, optimize protein-based products, and enhance the turnover of proteinaceous waste. Additionally, in the pharmaceutical industry, endopeptidases are being investigated for their therapeutic potential in the treatment of diseases where protein misfolding or aggregation plays a role. Thus, Endopeptidase, powder, represents a versatile tool in the arsenal of protein chemistry and engineering, driving advancements across multiple fields.

L-Asparaginase (EC 3.5.1.1) is an enzyme that catalyzes the following reaction: L-Asparagine + H2O → L-Aspartate + NH4+   One unit will yield 1.0 μmole of ammonia from L-asparagine per min at pH 8.6 and 37 °C.

RAB6B Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q9NRW1.

Transaminase with broad substrate specificity.

Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily.

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.

BoNT/C Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.

VRK1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

CREBBP Protein, Human, Recombinant (GST) is expressed in E.

Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI

Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Ubiquitin-Conjugating Enzyme E2 R2 (UBE2R2) is a modification enzyme that belongs to the ubiquitin-conjugating enzyme family.

PRKN Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides.

GBA2 Protein, Rat, Recombinant (His) is expressed in E.

RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family.

Iron-storage protein.

Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family.

Degradation of inorganic polyphosphates (polyP).

KLK10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.

IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells.

AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

CHEK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases.

HEXA Protein, Human, Recombinant (Subunit A, His) is expressed in Baculovirus insect cells with His tag.

DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to

Xylanase (Endo-1,4-β-xylanase, 1,4-β-D-Xylanxylanohydrolase, systematic name 4-β-D-xylan xylanohydrolase; EC 3.2.1.8) is an enzyme that digests polysaccharide xylan by hydrolyzing (1→4)-β-D-xylosidic linkages. One unit of Xylanase will hydrolyze 1.0 μmole of chromogenic substrate mimic per minute (available here) under optimal reaction conditions.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).

A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.

This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate.

NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family.

EGLN2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli with N-6xHis-SUMO. The accession number is Q96KS0.

dUTPase Protein, Human, Recombinant (His) is expressed in E.

Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha

Has cefotaxime-hydrolyzing activity.

Sphingomyelinase (SMase, Sphingomyelin phosphodiesterase, systematic name sphingomyelin cholinephosphohydrolase; EC 3.1.4.12) is an enzyme that hydrolyses sphingomyelin into phosphocholine and ceramide. One unit of sphingomyelinase will hydrolyze 1.0 µmole of chromogenic substrate analogue per minute at pH 7.4 and 37 °C.

Fukutin Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E.

Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan

CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the

Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.

JNK1 Protein, Human, Recombinant (His) is expressed in Baculovirus Insect Cells with N-6xHis. The accession number is P45983.

Dog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known.

HADHA Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mg

Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.