Enzyme

CBS Protein, Human, Recombinant (His) is expressed in Yeast.

Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.

Urokinase/uPA Protein, Human, Recombinant (Activated, His) is expressed in HEK293 Cells. The accession number is P00749-1.

PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

RIPK3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the accession number is Q9QZL0.

Adenylate Kinase 1 Protein, Rat, Recombinant (His) is expressed in E.

HSD3B1 Protein, Human, Recombinant (His & Myc) is expressed in E.

CKMT2 Protein, Rat, Recombinant (His) is expressed in E.

MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

SPO11 Protein, Human, Recombinant (His) is expressed in Baculovirus Insect Cells with C-6xHis. The accession number is Q9Y5K1.

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.

Cellulose catalase is an enzyme-based product, designed specifically to act as a catalyst in the oxidative processes associated with cellulose applications. It is derived from a microbial source, where bacilli or fungi are employed to produce robust catalase enzymes in a fermentation process. The mode of action involves the catalase enzyme’s ability to facilitate the decomposition of hydrogen peroxide into water and oxygen, thereby reducing oxidative damage during cellulose processing. Cellulose catalase finds extensive use in the textile and paper industries, where it is integral in the bleaching and de-inking processes. By catalyzing the breakdown of hydrogen peroxide, it ensures more efficient and safer removal of residual peroxide, promoting environmentally friendly practices. This biologically mediated reaction not only enhances the quality of cellulose-based products but also minimizes the need for chemical treatments. Moreover, its application extends to the improvement of fiber strength and brightness, establishing it as a crucial tool in sustainable industrial operations.

Thioredoxin reductase (TR, TrxR) (EC 1.8.1.9) is an enzyme that reduce thioredoxin using NADPH as a co-factor, and also contains FAD. One unit of thioredoxin reductase will raise increase light absorbance by 1.0 per minute at 412nm in the presence of thioredoxin and Ellman's reagent at pH 7.0 and 25 °C.

EP300 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is B2RWS6.

Has aminoprocollagen type I processing activity in the absence of ADAMTS2.

ST6GAL1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family.

beta-Galactosidase (EC 3.2.1.23, shortly beta-Gal, also know as lactase) catalyses the hydrolysis of beta-d-galactoside in the presence of water to galactose and alcohol, or lactose into glucose and galactose. beta-Gal has a molecular weight of 540,000 and is composed of four identical subunits of MW 135,000, each with an independent active site. The enzyme has divalent metals as cofactors, with chelated Mg2+ ions required to maintain active site conformation. The molecule contains numerous sulfhydryl groups and is glycosylated. This type of enzyme is found widespread in many microorganisms, plants and animals. In E. coli for instance, the beta-Gal protein is encoded by the lacZ gene. The enzyme is often used as a reporter for monitoring gene expression. beta-Gal also has good characteristics when conjugated to antibody molecules or streptavidin for use in ELISA kits. In addition, the enzyme is used to determine lactose in biological fluids and it is employed in food processing operations. Traditionally, beta-Gal activity is tested using the X-Gal or ONPG chromogenic substrates. But with the pioneering AquaSpark® beta-D-galactoside a substrate for beta-Gal detection becomes available that provides a previously unseen sensitivity. See here for futher informaiton on AquaSpark®: AquaSpark Chemiluminescence | Cymit Quimica

LPL Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag.

PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.

The improved, thermostable X-ShiningTM Luciferase is suitable for any luciferin-luciferase-based assay using D-luciferin (dLuc) or synthetic pro-luciferins (caged luciferins). Examples of its typical applications include ATP tests in hygiene monitoring, ATP tests in drug screenings and bacteria identification in microbial assays. The thermostable luciferase X-ShiningTM has been optimized by genetic engineering for strongly increased thermostability and storage stability. In temperature stress tests, the enzyme survives temperatures of 60°C for over an hour, whereas a wild type luciferase from firefly is inactivated after only a few minutes. The extraordinary stability makes it user-friendly and eliminates some of the main disadvantages and limitations of the commonly used wild type luciferase. X-ShiningTM Luciferase is supplied as aqueous solution with glycerol or as a lyophilisate (BX180145), and it may be stored for months at room temperature without significant loss of function. Find out more about our innovative X-Shining range here X-Shining | Innovation | Cymit Quimica Carbosynth.

Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family.

B3GALT5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

AK3L1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 25.3 kDa and the accession number is P27144-1.

Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.

Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain.

LYZL1 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids.

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.

Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and

LacBuster™-S 5000 is an enzymatic product, specifically a beta-lactamase, which originates from microbial sources known for their ability to produce enzymes that break down antibiotics. This product functions by hydrolyzing the beta-lactam ring of relevant antibiotics, thereby neutralizing their antibacterial activity. The primary applications of LacBuster™-S 5000 include its utilization in laboratory settings where beta-lactam antibiotics are present, allowing researchers to study microbial interactions without the interference of antibiotic activity. It is particularly valuable in experiments requiring selective deactivation of beta-lactam antibiotics to facilitate the growth of specific bacterial strains or when it’s necessary to clear antibiotics from samples without damaging the sample integrity. The use of this product is critical for understanding antibiotic resistance mechanisms and for experimental setups where antibiotic interference could skew results. As such, LacBuster™-S 5000 serves as a powerful tool in microbiological research and antibiotic resistance studies.

SMARCA2 Protein, Human, Recombinant (His) is expressed in Yeast.

Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.

N/A.

Pancreatin is an enzyme preparation, which is derived from the porcine pancreas. This product contains a mixture of several digestive enzymes, including amylase, lipase, and protease. It is typically obtained through the extraction and purification of these enzymes from the pancreas of pigs, providing a natural and effective source for enzymatic activity. The mode of action of pancreatin involves the breakdown of macronutrients in the digestive tract. Amylase catalyzes the hydrolysis of starch into sugars, lipase aids in the digestion of fats by breaking them down into fatty acids and glycerol, and protease facilitates the decomposition of proteins into peptides and amino acids. These actions collectively enhance the digestive process, optimizing nutrient absorption. Pancreatin is used extensively in scientific research and clinical settings to study digestive processes and enzyme deficiencies. It is also utilized in various pharmaceutical formulations aimed at treating conditions like pancreatitis and cystic fibrosis, where there is an insufficiency of natural digestive enzymes. Its broad application in both therapeutic and experimental contexts underlines its significance as a versatile biotechnological product.

Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus.

ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli.

HIBADH Protein, Human, Recombinant (His & Myc) is expressed in E.

Catalyzes the phosphorylation of dihydroxyacetone.

Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.

GSTA1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.

Key enzyme for ketone body catabolism.

OGDC-E1 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family.

CHST5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Thrombin-like snake venom serine protease that cleaves beta chain of fibrinogen (FGB), releasing fibrinopeptide B.

Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.

β-Glucosidase (β-D-glucosidase, systematic name β-D-glucoside glucohydrolase; EC 3.2.1.21) is an enzyme that catalyzes the release the terminal glucose monomers from cellulose and the other oligo- and poly saccharides with β-1,4-linked glucosyl residues. One Unit of β-Glucosidase will release 1.0 µmole of p-nitrophenol from the chromogenic substrate mimic p-nitrophenyl β-glucoside per minute under optimum conditions.

This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA.

Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues,

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The Lipase kit contains 25 lipases with different pH and temperature optima and substrate specificity properties.

PRSS56 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.

WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,

Converts monoacylglycerides to free fatty acids and glycerol.

Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The immobilized Lipase 070 has a temperature optimum at 45 °C and pH optimum between pH 5 and 8, and is covalently immobilized on a polymer resin. Immobilized lipases can be utilized in various reaction types, and are optimal for all reactions in organic solvents or solvent-free systems.

N/A.

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside

PKM2 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway.

Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the

PLAU/uPA Protein, Human, Recombinant (His) is expressed in HEK293 Cells with C-10xHis. The accession number is P00749.

CDK4 is a member of the Ser/Thr protein kinase family.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

May have a specific function in the mechanism or regulation of T-cell cytolytic activity.

UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of

RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family.

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.

Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit.

Probable methyltransferase.

1.

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

SGMS2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.

Lipase CR 02 is a high-purity enzyme preparation, which is derived from the microbial fermentation of selected fungal strains. With a mechanism involving the hydrolysis of ester bonds in lipids, Lipase CR 02 facilitates the conversion of triglycerides into glycerol and free fatty acids. This catalytic activity positions it as an essential tool in various biochemical and industrial applications. In research settings, Lipase CR 02 is employed for studying lipid metabolism and its regulation. Industrially, it is leveraged in the food, detergent, and pharmaceutical sectors, particularly in the synthesis of enantiomerically pure compounds and the modification of fats and oils. Its high specificity and stability under a range of conditions make it a versatile choice for diverse processes, including biotransformations and the production of biodiesel.

The secreted phospholipase A2-IIA (sPLA2-IIA, PLA2, systematic name phosphatidylcholine 2-acylhydrolase; EC 3.1.1.4) is an enzyme that catalyses the hydrolysis of glycerophospholipids at the sn2 position, yielding 1-acylglycerophosphocholine and a fatty acid. One unit of secreted phospholipase A2-IIA will hydrolyze 1.0 μmole of substrate per min under optimal conditions.

Pyruvate dehydrogenase kinase, isozyme 1, also known as [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial and PDK1, is a member of the PDK /

Catalyzes the ferrous insertion into protoporphyrin IX.

PR10A Protein, Coptis japonica, Recombinant (His & SUMO) is expressed in E. coli.

hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.

Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans.

Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-

Glutathione Synthetase belongs to the eukaryotic GSH synthase family.

Bisdemethoxycurcumin activates the AMPKα pathway;inhibits tyrosinas; targets pathways oxidative stress and apoptosis;anticancer.

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

ALDH1A2 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q62148.

Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli.

Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).

PTPRS Protein, Mus musculus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

MMP-24 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli.

SIRT5 Protein, Mouse, Recombinant (E.

Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily.

ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene.

GFER Protein, Rat, Recombinant (His & SUMO) is expressed in E.

Malic dehydrogenase is a mitochondrial isozyme and an important catalyst in the tricarboxylic acid cycle. The enzyme catalyzes the following reaction: Oxaloacetate + β-NADH → L-Malate + β-NADOne unit will convert 1.0 μmole of oxalacetate and β-NADH to L-malate and β-NAD per min at pH 7.5 at 25 °C.

Beta-lactamase enzyme targeting beta-lactam antibiotics

UBASH3B contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of

hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.

PARN Protein, Human, Recombinant (His) is expressed in E.

KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

HER3/ERBB3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Kallikrein 15/KLK15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

One unit of alkaline phosphatase (EC 3.1.3.1) will hydrolyze 1.0 µmol of 4-nitrophenyl phosphate per min at 25°C and pH 9.6.

This is a non-secretory ribonuclease.