Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR
- Cell wall
- CXCR
- gp120/CD4
- IL Receptor
- IκB/IKK
- LTR
- MALT
- MRP
- NADPH-oxidase
- NF-κB
- NOD
- NOS
- Nrf2
- PGE Synthase
- ROS
- TGF-beta/Smad
- Thioredoxin
- TLR
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Products of "Immunology and Inflammation"
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Specnuezhenide
CAS:Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.Formula:C31H42O17Purity:98% - 99.12%Color and Shape:SolidMolecular weight:686.66Ref: TM-T3803
2mg38.00€5mg52.00€10mg88.00€25mg164.00€50mg233.00€100mg344.00€500mg830.00€1mL*10mM (DMSO)82.00€Damascenone
CAS:Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.Formula:C13H18OPurity:98.03%Color and Shape:Colorless LiquidMolecular weight:190.28Moroxydine hydrochloride
CAS:Moroxydine hydrochloride (ABOB hydrochloride) is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines.Formula:C6H13N5O·HClPurity:99.15%Color and Shape:White Crystalline PowderMolecular weight:207.66C-di-IMP disodium
C-di-IMP disodium, a STING agonist, is utilized in tumor research [1].Purity:98%Color and Shape:Odour Solidtaraxasteryl acetate
CAS:Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations.Formula:C32H52O2Purity:98% - 99.02%Color and Shape:SolidMolecular weight:468.75PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurity:98.04% - 99.91%Color and Shape:SolidMolecular weight:535.98Ref: TM-T4583
1mg40.00€2mg51.00€5mg85.00€10mg117.00€25mg212.00€50mg378.00€100mg552.00€500mg1,169.00€1mL*10mM (DMSO)128.00€Tenofovir exalidex
CAS:Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistantFormula:C28H52N5O5PPurity:99.54%Color and Shape:SolidMolecular weight:569.72Ginkgolide A
CAS:Formula:C20H24O9Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:408.40Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14diABZI-V/C-DBCO
Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.Formula:C78H89N19O13Color and Shape:SolidMolecular weight:1500.66Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purity:100% - 99.61%Color and Shape:SolidMolecular weight:256.25Kuwanon E
CAS:Kuwanon E blocks cholinesterase; K i 3.1-37.5 μM for AChE, 1.7-19.1 μM for BChE; stops MUC5AC production in NCI-H292 cells.Formula:C25H28O6Purity:95%Color and Shape:SolidMolecular weight:424.49NF-κB/MAPK-IN-1
CAS:NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).Formula:C27H27NO7Purity:97.03%Color and Shape:SolidMolecular weight:477.51Ref: TM-T63119
1mg47.00€2mg60.00€5mg87.00€10mg154.00€25mg329.00€50mg492.00€100mg710.00€1mL*10mM (DMSO)93.00€6,11-Dihydro-11-oxodibenzo[b,e]oxepin-2-acetic Acid
CAS:Formula:C16H12O4Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:268.27Sacituzumab tirumotecan
CAS:Sacituzumab tirumotecan (SKB264/MK-2870) is a TROP2ADC utilized in research studies targeting triple-negative breast cancer (TNBC).Color and Shape:LiquidPSMA-ALB-56
CAS:PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.Formula:C66H95N11O18Color and Shape:SolidMolecular weight:1330.52Histamine Diphosphate
CAS:Formula:C5H9N3·2H3PO4Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:307.14Anti-MRC2/CD280 Antibody
Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.Color and Shape:Odour LiquidR 61837
CAS:R 61837 is a novel rhinovirus inhibitor, a substituted phenylpyridazinamine, with antiviral activity.Formula:C16H20N4OPurity:99.56%Color and Shape:SolidMolecular weight:284.36IQP-0528
CAS:IQP-0528: Potent NNRTI, blocks HIV entry, microbicidal gel, EC50: 0.2 nM for HIV-1, 100 nM for HIV-2.Formula:C20H24N2O3Purity:100% - 98.40%Color and Shape:SolidMolecular weight:340.42Ref: TM-T27625
1mg74.00€5mg160.00€10mg226.00€25mg383.00€50mg530.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)164.00€NLRP3-IN-65
CAS:NLRP3-IN-65 (compound 41) is a potent inhibitor of NLRP3.Formula:C20H24F3N3OColor and Shape:SolidMolecular weight:379.42CPUY192018
CAS:CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions, and can be used to study mitochondrial autophagy.Formula:C28H26N2O10S2Purity:98.9%Color and Shape:SolidMolecular weight:614.64Curcumin (Natural)
CAS:Formula:C21H20O6Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39Cusatuzumab
CAS:Cusatuzumab (ARGX-110) is a human CD70 monoclonal antibody with enhanced antibody-dependent cytotoxic activity.Purity:95% - 95%Color and Shape:LiquidIRAK-1-4 Inhibitor I
CAS:IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.Formula:C20H21N5O4Purity:100% - 99.89%Color and Shape:SolidMolecular weight:395.41Ref: TM-T2457
1mg44.00€5mg79.00€10mg110.00€25mg224.00€50mg376.00€100mg540.00€500mg1,130.00€1mL*10mM (DMSO)79.00€(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
CAS:Formula:C44H69NO12Purity:98%Color and Shape:SolidMolecular weight:804.0182Ref: IN-DA0039L0
1g160.00€5g687.00€10gTo inquire25gTo inquire10mg45.00€50mg50.00€100mg73.00€250mg113.00€Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Formula:C14H14N2Purity:99.25%Color and Shape:White Crystalline Powder SolidMolecular weight:210.27Tiopronin
CAS:Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stoneFormula:C5H9NO3SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:163.19CpG ODN 10101
CAS:CpG ODN 10101 (CPG 10101) is an oligodeoxynucleotide agonist of TLR9 with antiviral activity for the treatment of chronic infections.Purity:94.06%Color and Shape:SolidStipuleanoside R2
CAS:Stipuleanoside R2 is a triterpenoid saponin that inhibits NF-κB activation and has potential applications in inflammation, immunology, and cancer research.Formula:C53H84O23Purity:98%Color and Shape:SolidMolecular weight:1089.22D228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Formula:C22H28O12Purity:99.91%Color and Shape:SolidMolecular weight:484.45Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1SDH-IN-23
SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.Formula:C19H11ClF6N2O2Color and Shape:SolidMolecular weight:448.75BMS-905
CAS:BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members.Formula:C23H29N3Purity:99.85%Color and Shape:SoildMolecular weight:347.5SM-324405
CAS:SM-324405 is an agonist of TLR7.Formula:C19H23N5O4Purity:97.83%Color and Shape:SolidMolecular weight:385.42Ref: TM-T7860
1mg37.00€5mg78.00€10mg113.00€25mg202.00€50mg324.00€100mg462.00€200mg645.00€1mL*10mM (DMSO)87.00€AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formula:C18H28Cl3N5Purity:99.74%Color and Shape:SolidMolecular weight:420.81Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-
CAS:Formula:C17H21NOPurity:95%Color and Shape:LiquidMolecular weight:255.3547Paederoside
CAS:Paederoside deters beetles, isolated from aphids, and inhibits tumor-promotion in Epstein-Barr virus.Formula:C18H22O11SPurity:97.81% - 99.90%Color and Shape:SolidMolecular weight:446.43Ref: TM-T3S0872
1mg48.00€5mg88.00€10mg128.00€25mg205.00€50mg303.00€100mg445.00€200mg655.00€1mL*10mM (DMSO)99.00€iNOS inhibitor-10
CAS:iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].Formula:C22H23N3O2SPurity:98%Color and Shape:SolidMolecular weight:393.5W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formula:C30H37ClN2O2Purity:95.62%Color and Shape:SolidMolecular weight:493.08Ref: TM-T17250
1mg85.00€5mg127.00€10mg187.00€25mg335.00€50mg518.00€100mg747.00€1mL*10mM (DMSO)165.00€Sootepin D
CAS:Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.Formula:C31H48O4Purity:98%Color and Shape:SolidMolecular weight:484.71IMD-0560
CAS:IMD-0560 is a novel inhibitor of IκB kinase β.Formula:C15H8BrF6NO2Purity:99.51%Color and Shape:SolidMolecular weight:428.12Betamethasone Valerate
CAS:Formula:C27H37FO6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:476.59Dapansutrile
CAS:Formula:C4H7NO2SPurity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:133.17Anti-inflammatory agent 46
CAS:Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energiesFormula:C24H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:434.48Corydine
CAS:Corydine: adrenolytic, weak cholinergic; antimicrobial, antineoplastic; irritant, respiratory/CNS effects; alters rabbit blood pressure IV.Formula:C20H23NO4Purity:98%Color and Shape:SolidMolecular weight:341.4BMS-986449
BMS-986449 is a CELMoD-type molecular gel that enhances anti-tumor by directing the E3 ubiquitin ligase, Cereblon, to degrade IKZF2 (Helios) and IKZF4 (Eos).Formula:C21H21FN4O3Color and Shape:SolidMolecular weight:396.42CD73-IN-4
CAS:CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitorFormula:C16H23ClN5O7PPurity:98.2%Color and Shape:SolidMolecular weight:463.81Ref: TM-T9210
1mg97.00€5mg243.00€10mg393.00€25mg702.00€50mg938.00€100mg1,320.00€1mL*10mM (DMSO)245.00€Biricodar dicitrate
CAS:Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.Formula:C46H57N3O21Purity:98.67% - 99.34%Color and Shape:SolidMolecular weight:987.95Goshonoside F5
CAS:Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.Formula:C32H54O13Purity:98%Color and Shape:SolidMolecular weight:646.771Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Formula:C16H12O5Purity:100% - 99.79%Color and Shape:SolidMolecular weight:284.26Ref: TM-T4S0969
1mg70.00€5mg187.00€10mg279.00€25mg472.00€50mg658.00€100mg933.00€1mL*10mM (DMSO)187.00€Dexamethasone Sodium Phosphate
CAS:Dexamethasone Sodium Phosphate (Dexadreson) is a powerful anti-inflammatory and immunosuppressant synthetic glucocorticoid.Formula:C22H30FO8P·2NaPurity:99.27%Color and Shape:SolidMolecular weight:516.4Ref: TM-T2S0843
1mg80.00€5mg180.00€10mg298.00€25mg502.00€50mg715.00€100mg938.00€200mg1,311.00€1mL*10mM (DMSO)170.00€Galectin-3/galectin-8-IN-1
Galectin-3/galectin-8-IN-1 (Compound 53) serves as a dual inhibitor of the Galectin-3 and galectin-8 C-terminal domains, exhibiting dissociation constants (Kd)Formula:C22H13Cl2N3O4S2Purity:98%Color and Shape:SolidMolecular weight:518.39Carbamimidothioic acid, N-[(4-chlorophenyl)methyl]-, 3-(1H-imidazol-5-yl)propyl ester
CAS:Formula:C14H17ClN4SPurity:95%Color and Shape:SolidMolecular weight:308.8296CID-2858522
CAS:CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Formula:C28H39N3O3Purity:96.11%Color and Shape:SolidMolecular weight:465.63Molsidomine
CAS:Molsidomine, an oral vasodilator, turns into linsidomine in the liver, releasing NO for prolonged effects.Formula:C9H14N4O4Purity:100% - 99.98%Color and Shape:Colorless Or White Crystalline PowderMolecular weight:242.23Questinol
CAS:Questinol fights obesity, reduces inflammation and pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), and inhibits NO and PGE2 in cells.Formula:C16H12O6Purity:98%Color and Shape:SolidMolecular weight:300.26Brincidofovir
CAS:Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir.Formula:C27H52N3O7PPurity:98% - 99.62%Color and Shape:SolidMolecular weight:561.69Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.23% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg145.00€2mg215.00€5mg314.00€10mg474.00€25mg808.00€50mg1,111.00€100mg1,501.00€1mL*10mM (DMSO)324.00€BMS-986235
CAS:BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.Formula:C18H17F2N3O3Purity:99.65%Color and Shape:SolidMolecular weight:361.34Ref: TM-T39789
1mg70.00€5mg154.00€10mg243.00€25mg435.00€50mg610.00€100mg800.00€1mL*10mM (DMSO)166.00€Diphenhydramine Hydrochloride
CAS:Formula:C17H21NO·HClPurity:>98.0%(T)(HPLC)Color and Shape:White powder to crystalMolecular weight:291.82C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.74Lusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Purity:95% - 95%Color and Shape:Liquid5-Fluorocytidine
CAS:5-Fluorocytidine with antiviral activityFormula:C9H12FN3O5Purity:99.23%Color and Shape:White PowderMolecular weight:261.21IRAK4-IN-27
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 nM.Formula:C23H22N6O3Purity:98%Color and Shape:SolidMolecular weight:430.466-Mercaptopurine Monohydrate
CAS:Formula:C5H4N4S·H2OPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Yellow powder to crystalMolecular weight:170.20Cantleyoside
CAS:Cantleyoside, a natural cyclic enol ether terpene glycoside from Pterocephalus hookeri, can activate of the AMPK/Sirt1/NF-κB signaling pathway.Formula:C33H46O19Purity:99.85%Color and Shape:SolidMolecular weight:746.71Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Formula:C30H34N4O6SPurity:≥98%Color and Shape:SolidMolecular weight:578.68Lintuzumab
CAS:Lintuzumab (HuM-195) is an uncoupled humanized mouse monoclonal antibody against CD33 with anti-leukemic activity.Purity:≥95% (SDS-PAGE/SEC-HPLC) - ≥95% (SDS-PAGE/SEC-HPLC)Color and Shape:LiquidBAL-0028
CAS:BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.Formula:C24H22FN3O2Purity:99.16%Color and Shape:SoildMolecular weight:403.45C5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formula:C54H70N16O11·xC2H4O2Color and Shape:SolidMolecular weight:1119.23 (free base)GPS491
CAS:GPS491 has antiviral activity and inhibits HIV-1, adenovirus, and coronavirus replication by altering RNA processing.Formula:C13H5F6N3OS2Purity:98.81%Color and Shape:SolidMolecular weight:397.32Ref: TM-T40293
1mg333.00€5mg922.00€10mg1,140.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg6,613.00€Deflazacort
CAS:Formula:C25H31NO6Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:441.524-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine
CAS:Formula:C16H20N2Purity:>98.0%(GC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:240.35Gardiquimod
CAS:Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.Formula:C17H23N5OPurity:98.02% - 99.47%Color and Shape:SolidMolecular weight:313.4Methanone, (2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]-
CAS:Formula:C23H24Cl2N2O3Purity:99%Color and Shape:SolidMolecular weight:447.3543Physalin O
CAS:Physalin O has anti-inflammatory properties, binds with GSH, and inhibits NO production.Formula:C28H32O10Purity:98%Color and Shape:SolidMolecular weight:528.5542H-1,2,4-Benzothiadiazine-7-sulfonamide,3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide
CAS:Formula:C14H16ClN3O4S2Purity:95%Color and Shape:SolidMolecular weight:389.87756-Hydroxyflavone
CAS:Formula:C15H10O3Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:238.24JTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.Formula:C17H13NaO4Purity:95.08%Color and Shape:SolidMolecular weight:304.27Bilastine
CAS:Formula:C28H37N3O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:463.62GSK547
CAS:GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.Formula:C20H18F2N6OPurity:99.17%Color and Shape:SolidMolecular weight:396.39Gliotoxin
CAS:Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.Formula:C13H14N2O4S2Purity:98%Color and Shape:SolidMolecular weight:326.393-O-Methylquercetin tetraacetate
CAS:Quercetin 3-O-methyl ether inhibits PDE3/4, may treat asthma and airway hyperresponsiveness.Formula:C24H20O11Purity:98%Color and Shape:SolidMolecular weight:484.41NLRP3-IN-51
NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.Color and Shape:Odour SolidClemizole Hydrochloride
CAS:Formula:C19H20ClN3·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:362.302'-β-C-Methyl inosine
CAS:2'-beta-C-Methyl inosine (2'-C-Methyl inosine) is an HCV RNA polymerase inhibitor with antiviral activity and may be used in studies to treat hcv infections.Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25HS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.Formula:C17H16N4O3Purity:97.34%Color and Shape:SolidMolecular weight:324.33RIP1 kinase inhibitor 4
CAS:RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formula:C67H127F3N10O14SPurity:99.90%Color and Shape:SoildMolecular weight:1385.84Montelukast Sodium
CAS:Formula:C35H35ClNNaO3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:608.17Oxamisole TFA
Oxamisole TFA is an orally available T-cell immune repair agent.Formula:C17H21F3N2O4Purity:100% - 96.95%Color and Shape:SoildMolecular weight:374.35Viroxime
CAS:Viroxime has anti-rhinoviral activity and may be used to study poliovirus infections.Formula:C17H18N4O3SPurity:100%Color and Shape:SoildMolecular weight:358.42WIN 54954
CAS:WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.Formula:C18H20Cl2N2O3Purity:98.58%Color and Shape:SolidMolecular weight:383.27Ref: TM-T61652
1mg57.00€2mg81.00€5mg120.00€10mg188.00€25mg354.00€50mg588.00€100mg1,035.00€500mg2,118.00€1mL*10mM (DMSO)133.00€Minocycline Hydrochloride
CAS:Formula:C23H27N3O7·HClPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:493.94CHPG sodium salt
CAS:CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways.Formula:C8H7ClNNaO3Purity:100%Color and Shape:SolidMolecular weight:223.59Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formula:C25H31ClN2O4Purity:98.32% - 99.87%Color and Shape:SolidMolecular weight:458.98Ref: TM-T9189
1mg59.00€5mg127.00€10mg205.00€25mg371.00€50mg620.00€100mg1,026.00€200mg1,388.00€1mL*10mM (DMSO)128.00€LDC7559
CAS:LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.Formula:C20H19N3O3Purity:99.47%Color and Shape:SoildMolecular weight:349.38Ref: TM-T11828
1mg79.00€5mg187.00€10mg311.00€25mg530.00€50mg748.00€100mg1,064.00€1mL*10mM (DMSO)215.00€
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