Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR
- Cell wall
- CXCR
- gp120/CD4
- IL Receptor
- IκB/IKK
- LTR
- MALT
- MRP
- NADPH-oxidase
- NF-κB
- NOD
- NOS
- Nrf2
- PGE Synthase
- ROS
- TGF-beta/Smad
- Thioredoxin
- TLR
Show 11 more subcategories
Products of "Immunology and Inflammation"
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Promethazine Hydrochloride
CAS:Formula:C17H20N2S·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:320.88SP4206
CAS:SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)Formula:C30H37Cl2N7O6Purity:98%Color and Shape:SolidMolecular weight:662.56Mirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Purity:95% - 95%Color and Shape:LiquidhPGDS-IN-1
CAS:hPGDS-IN-1 is a hPGDS inhibitor.Formula:C22H20N6O3Purity:100% - 99.74%Color and Shape:SolidMolecular weight:416.43Olopatadine Hydrochloride
CAS:Formula:C21H23NO3·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:373.88FPL 55712
CAS:FPL 55712 is a leukotriene receptor and SRS-A antagonist that inhibits bronchoconstriction and can be used in studies of asthma and coronary artery thrombosis.Formula:C27H30O9Purity:100.00% - 98.87%Color and Shape:SolidMolecular weight:498.52Anti-inflammatory agent 60
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-cateninPurity:98%Color and Shape:Odour Solid11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Formula:C21H28O5Purity:98%Color and Shape:SolidMolecular weight:360.4440Adenosine N1-oxide
CAS:Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reducedFormula:C10H13N5O5Purity:99.24%Color and Shape:SolidMolecular weight:283.24Ref: TM-T23636
1mg66.00€2mg95.00€5mg120.00€10mg168.00€25mg304.00€50mg432.00€100mg635.00€1mL*10mM (DMSO)124.00€Indacaterol
CAS:Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.Formula:C24H28N2O3Purity:100.00% - 99.63%Color and Shape:SolidMolecular weight:392.49Mitraphylline
CAS:Mitraphylline inhibits growth in human glioma/neuroblastoma cells and reduces inflammation in neutrophils.Formula:C21H24N2O4Purity:99.89% - 99.89%Color and Shape:SolidMolecular weight:368.43Ref: TM-TN1933
1mg48.00€5mg127.00€10mg216.00€25mg369.00€50mg543.00€100mg772.00€1mL*10mM (DMSO)137.00€GSK872 HCl(1346546-69-7 free base)
CAS:GSK872 HCl(1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.Formula:C19H18ClN3O2S2Purity:99%Color and Shape:SolidMolecular weight:419.94Pristimerin
CAS:Pristimerin has anticancer properties, counters hypoxia-induced cancer spread, and reduces inflammation by inhibiting ROS/IKK/NF-κB pathways.Formula:C30H40O4Purity:99.43% - 99.59%Color and Shape:SolidMolecular weight:464.64Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Formula:C27H24BrN7O3Purity:99.51%Color and Shape:SolidMolecular weight:574.43Ref: TM-T38332
1mg111.00€5mg255.00€10mg380.00€25mg672.00€50mg950.00€100mg1,235.00€200mg1,673.00€1mL*10mM (DMSO)316.00€AR-9281
CAS:AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetesFormula:C18H29N3O2Purity:99.79%Color and Shape:SolidMolecular weight:319.44Ref: TM-T14315
2mg34.00€5mg52.00€10mg85.00€25mg156.00€50mg239.00€100mg378.00€200mg550.00€1mL*10mM (DMSO)58.00€Benzydamine Hydrochloride
CAS:Formula:C19H23N3O·HClPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:345.87Enokizumab
CAS:Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.Purity:SDS-PAGE:95% SEC-HPLC:99.23%Color and Shape:LiquidMolecular weight:145.98 kDaPomalidomide
CAS:Formula:C13H11N3O4Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalineMolecular weight:273.25IL-17A inhibitor 1
CAS:IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.Formula:C24H27F5N8O4Purity:99.37% - 99.37%Color and Shape:SolidMolecular weight:586.51Triamcinolone Acetonide
CAS:Formula:C24H31FO6Purity:>98.0%(E)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:434.50RIP1 kinase inhibitor 6
CAS:RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1Formula:C19H18F2N2O3Purity:98%Color and Shape:SolidMolecular weight:360.35Lornoxicam
CAS:Formula:C13H10ClN3O4S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Yellow powder to crystalMolecular weight:371.81GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Formula:C17H17BrF3N7O2SPurity:99.46% - ≥98%Color and Shape:SolidMolecular weight:520.33Ref: TM-T5540
1mg47.00€2mg59.00€5mg92.00€10mg131.00€25mg215.00€50mg378.00€100mg567.00€1mL*10mM (DMSO)96.00€APX-115
CAS:APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).Formula:C17H18ClN3OPurity:99.68%Color and Shape:SolidMolecular weight:315.8Ref: TM-T10354
1mg35.00€5mg80.00€10mg116.00€25mg235.00€50mg351.00€100mg500.00€500mg1,017.00€1mL*10mM (DMSO)97.00€TBK1/IKKε-IN-2
CAS:TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.Formula:C26H27N5O3Purity:98.89%Color and Shape:SolidMolecular weight:457.52Ref: TM-T15559
1mg92.00€5mg188.00€10mg305.00€25mg487.00€50mg660.00€100mg847.00€1mL*10mM (DMSO)188.00€Mycophenolic Acid
CAS:Formula:C17H20O6Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:320.34GSK2256294A
CAS:GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.Formula:C21H24F3N7OPurity:98.65% - 99.27%Color and Shape:SolidMolecular weight:447.46NLRP3-IN-49
NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.Color and Shape:Odour SolidChloranil
CAS:Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.Formula:C6Cl4O2Purity:99.38%Color and Shape:SolidMolecular weight:245.88NLRP3-IN-20
CAS:NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1βFormula:C22H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:413.531H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-
CAS:Formula:C13H11N3O4Purity:98%Color and Shape:SolidMolecular weight:273.2441Lupeol acetate
CAS:Lupeol acetate is anti-cancer, anti-inflammatory, anti-diabetic, anti-fertility and inhibits rheumatoid arthritis by down-regulating inflammatory cytokines.Formula:C32H52O2Purity:99.84%Color and Shape:SolidMolecular weight:468.75C12-rrw-NH2
C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.Formula:C35H58N10O5Color and Shape:SolidMolecular weight:698.9TRIMETHYLVINYLAMMONIUM BROMIDE
CAS:Formula:C5H12BrNPurity:97%Color and Shape:SolidMolecular weight:166.05959,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-,(3b,6a,16b,20R,24S)-
CAS:Formula:C30H50O5Purity:98%Color and Shape:SolidMolecular weight:490.715Banoxantrone dihydrochloride
CAS:Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.Formula:C22H30Cl2N4O6Purity:98.84% - 98.93%Color and Shape:SolidMolecular weight:517.4Ref: TM-T10459
5mg79.00€10mg97.00€25mg165.00€50mg235.00€100mg346.00€500mg832.00€1mL*10mM (DMSO)96.00€Oleclumab
CAS:Oleclumab (MEDI9447) is a human anti-CD73 monoclonal antibody with anticancer activity for the study of metastatic desmoplastic resistant prostate cancer.Purity:95%Color and Shape:LiquidMolecular weight:143.14 kDaSBI-0640726
CAS:SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation complex by inhibiting the AKT and NF-kB signaling pathways. Additionally, SBI-0640726 inhibits the growth of melanoma with NRAS and BRAF mutations in vitro.Formula:C23H15ClN2O2Color and Shape:SolidMolecular weight:386.83PTIO
CAS:PTIO is a specific scavenger of NO.Formula:C13H17N2O2Purity:98%Color and Shape:SolidMolecular weight:233.29CU-CPT22
CAS:CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).Formula:C19H22O7Purity:98.66%Color and Shape:SolidMolecular weight:362.37Ref: TM-T15020
1mg52.00€2mg70.00€5mg99.00€10mg168.00€25mg313.00€50mg469.00€100mg682.00€200mg938.00€1mL*10mM (DMSO)114.00€Flavokawain C
CAS:Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM.Formula:C17H16O5Purity:98%Color and Shape:SolidMolecular weight:300.31Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purity:98%Color and Shape:SolidMolecular weight:1322HPN-01
CAS:HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.Formula:C19H16ClN3O3SPurity:98.07%Color and Shape:SolidMolecular weight:401.873-Bromo-7-nitroindazole
CAS:3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.Formula:C7H4BrN3O2Purity:97.44%Color and Shape:Yellowish SolidMolecular weight:242.03NLRP3-IN-46
NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.Color and Shape:Odour SolidDelmitide acetate
CAS:Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties.Formula:C61H109N17O13Purity:98%Color and Shape:SolidMolecular weight:1288.62Hydrocortisone 21-Hemisuccinate
CAS:Formula:C25H34O8Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:462.54Allopurinol Sodium
CAS:Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.Formula:C5H4N4NaOPurity:99.92%Color and Shape:SolidMolecular weight:159.1(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS:(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.Formula:C18H21NO4Purity:98%Color and Shape:SoildMolecular weight:315.36
