
Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR
- Cell wall
- CXCR
- gp120/CD4
- IL Receptor
- IκB/IKK
- LTR
- MALT
- MRP
- NADPH-oxidase
- NF-κB
- NOD
- NOS
- Nrf2
- PGE Synthase
- ROS
- TGF-beta/Smad
- Thioredoxin
- TLR
Show 11 more subcategories
Products of "Immunology and Inflammation"
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Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Formula:C34H44O19Purity:98% - 98.78%Color and Shape:SolidMolecular weight:756.7GSK-843
CAS:GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be used as an adjunctive treatment for inflammation.Formula:C19H15N5S2Purity:99.18%Color and Shape:SolidMolecular weight:377.492-Pyridinepropanamine, N,N-dimethyl-γ-phenyl-, (2Z)-2-butenedioate (1:1)
CAS:Formula:C20H24N2O4Purity:98%Color and Shape:SolidMolecular weight:356.4156Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurity:99.76% - 99.83%Color and Shape:White SolidMolecular weight:249.33Ref: TM-T1934
2mg35.00€5mg50.00€10mg66.00€25mg85.00€50mg124.00€100mg197.00€200mg255.00€1mL*10mM (DMSO)62.00€NLRP3-IN-21
CAS:NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.Formula:C20H13Cl2F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:529.32Tyramine
CAS:Formula:C8H11NOPurity:>98.0%(GC)(T)Color and Shape:White to Brown powder to crystalMolecular weight:137.18LAG-3 cyclic peptide inhibitor C25
LAG-3cyclic peptide inhibitor C25 is an inhibitor of LAG-3. It demonstrates a high affinity for human LAG-3 protein with a dissociation constant (Kd) of 0.66 μM. This compound can block the interaction between LAG-3 and HLA-DR (MHC-II), thereby activating CD8+ T cells. LAG-3cyclic peptide inhibitor C25 is applicable in tumor research.Formula:C43H68N12O12S3Color and Shape:SolidMolecular weight:1041.27Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Formula:C40H36O12Purity:97.76% - 98.54%Color and Shape:SolidMolecular weight:708.71IRAK4-IN-4
CAS:IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4)Formula:C22H16N2O2Purity:99.52%Color and Shape:SolidMolecular weight:340.37Ref: TM-T11673
1mg64.00€5mg145.00€10mg212.00€25mg378.00€50mg567.00€100mg815.00€200mg1,093.00€1mL*10mM (DMSO)160.00€BAY 11-7082
CAS:Formula:C10H9NO2SPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:207.25NLRP3-IN-45
NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.Formula:C27H30FNO6Color and Shape:SolidMolecular weight:483.53Factor B-IN-5
CAS:Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Formula:C27H32N2O4Purity:98.53%Color and Shape:SoildMolecular weight:448.55Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurity:98.35% - 99.95%Color and Shape:Needles From Benzene Or Alcohol SolidMolecular weight:234.34Oridonine
CAS:Formula:C20H28O6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:364.44IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63Ref: TM-T6176
1mg40.00€2mg52.00€5mg88.00€10mg139.00€25mg245.00€50mg406.00€100mg607.00€200mg845.00€1mL*10mM (DMSO)87.00€Flumetasone
CAS:Formula:C22H28F2O5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:410.46α-Gracinoic acid
CAS:α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.Formula:C29H42O4Color and Shape:SolidMolecular weight:454.64CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purity:99.62%Color and Shape:SolidMolecular weight:491.5Ref: TM-T9027
1mg35.00€2mg52.00€5mg77.00€10mg87.00€25mg170.00€50mg311.00€100mg535.00€1mL*10mM (DMSO)84.00€Edoxudine
CAS:Edoxudine, a thymidine analog, combats herpes simplex and modulates 5-fluorouracil, boosting its effectiveness and safety.Formula:C11H16N2O5Purity:99.94%Color and Shape:SolidMolecular weight:256.26Lobeglitazone Sulfate
CAS:Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.Formula:C24H26N4O9S2Purity:98.69%Color and Shape:SolidMolecular weight:578.61NLRP3-IN-44
CAS:NLRP3-IN-44 (compound P33), an orally active (approximately 62%) and potent inhibitor of NLRP3, exhibits a dissociation constant (K D) of 17.5 nM. This compound is crucial in the research of diseases mediated by the NLRP3 inflammasome.Formula:C25H30N4O3Color and Shape:SolidMolecular weight:434.53PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52Dexamethasone
CAS:Formula:C22H29FO5Purity:>99.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:392.47RI-962
CAS:RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Formula:C28H28N6O2Purity:99.39%Color and Shape:SoildMolecular weight:480.56Dihydromyricetin
CAS:Formula:C15H12O8Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:320.25Serotonin Hydrochloride
CAS:Formula:C10H12N2O·HClPurity:>97.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:212.68Chrysosplenol D
CAS:Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.Formula:C18H16O8Purity:97.87%Color and Shape:SolidMolecular weight:360.31Rapamycin
CAS:Formula:C51H79NO13Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:914.19MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA is the trifluoroacetate form of MC-Val-Cit-PAB-Amide-TLR7 agonist 4,a HER2-TLR7 and HER2- TLR8 immune agonist complexes.Formula:C54H73F3N12O13Purity:99.67%Color and Shape:SolidMolecular weight:1155.22Ref: TM-T74468L
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€Celecoxib
CAS:Formula:C17H14F3N3O2SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:381.37Hypoxystat
CAS:Hypoxystat increases the affinity of hemoglobin for oxygen, thereby reducing the release of oxygen to tissues and inducing tissue hypoxia. [Hypoxystat] can alleviate mitochondrial disorder Leigh syndrome in Ndufs4 gene knockout mouse models. Hypoxystat is orally active.Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.395CID1231538
CAS:CID1231538 is a potent GPR35 antagonist.Formula:C26H22ClN3O3S2Purity:98.79%Color and Shape:SolidMolecular weight:524.05Procyanidin A2
CAS:Procyanidin A2: precursor to a valerolactone, with antioxidant, anti-inflammatory, anti-diabetic properties; aids liver repair.Formula:C30H24O12Purity:98.51% - 98.78%Color and Shape:SolidMolecular weight:576.5Ref: TM-TN1132
1mg88.00€5mg235.00€10mg350.00€25mg585.00€50mg825.00€100mg1,111.00€1mL*10mM (DMSO)298.00€Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-,hydrochloride, hydrate (2:3)
CAS:Formula:C42H50Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:701.764Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formula:C2H4Cl3O2Te·H4NPurity:≥95%Color and Shape:SolidMolecular weight:312.05DUPA(OtBu)-OH
CAS:DUPA(OtBu)-OH, a DUPA precursor, targets PSMA with high affinity (Ki=8nM) to deliver Docetaxel for prostate cancer therapy.Formula:C23H40N2O9Purity:97.29%Color and Shape:SolidMolecular weight:488.57Ref: TM-T11122
1mg34.00€5mg74.00€10mg111.00€25mg178.00€50mg250.00€100mg353.00€200mg502.00€1mL*10mM (DMSO)81.00€Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurity:99.95%Color and Shape:SolidMolecular weight:288.824-Aminosalicylic Acid
CAS:Formula:C7H7NO3Purity:>98.0%(T)Color and Shape:White to Light gray to Light orange powder to crystalMolecular weight:153.14Fluticasone Propionate
CAS:Formula:C25H31F3O5SPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:500.57CDDO-EA
CAS:CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Formula:C33H46N2O3Purity:98.54%Color and Shape:SolidMolecular weight:518.73Ref: TM-T10733
1mg85.00€5mg169.00€10mg298.00€25mg512.00€50mg732.00€100mg944.00€200mg1,264.00€1mL*10mM (DMSO)187.00€BBIQ
CAS:BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1Formula:C21H22N4Purity:98.02%Color and Shape:SolidMolecular weight:330.43Betamethasone 21-Acetate
CAS:Formula:C24H31FO6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:434.50NecroX-7
CAS:NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Formula:C24H29N3O3SPurity:98.08%Color and Shape:SolidMolecular weight:439.57BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Formula:C18H15BrCl2N2O2Purity:100%Color and Shape:SolidMolecular weight:442.13Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurity:99.89% - ≥98%Color and Shape:SolidMolecular weight:290.48Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35Pemetrexed
CAS:Formula:C20H21N5O6Purity:>98.0%(T)(HPLC)Color and Shape:White to Blue powder to crystalMolecular weight:427.42YQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Formula:C27H29ClN2O4S2Purity:99.89%Color and Shape:SolidMolecular weight:545.11Ref: TM-T13375
1mg56.00€5mg119.00€10mg187.00€25mg305.00€50mg512.00€100mg738.00€1mL*10mM (DMSO)144.00€Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formula:C24H21F2NO3Purity:97.28% - 99.97%Color and Shape:SolidMolecular weight:409.43Ref: TM-T1593
1g283.00€10mg48.00€25mg62.00€50mg77.00€100mg87.00€200mg125.00€500mg197.00€1mL*10mM (DMSO)55.00€Aminoguanidine hydrochloride
CAS:Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.Formula:CH6N4·HClPurity:99.80%Color and Shape:White To Off-White SolidMolecular weight:110.55