NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
Sort by
SZM-1209
CAS:SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.Formula:C31H29F5N4O5S2Purity:98%Color and Shape:SolidMolecular weight:696.71Penehyclidine hydrochloride
CAS:Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.Formula:C20H30ClNO2Purity:99.7%Color and Shape:SolidMolecular weight:351.91Isophysalin A
CAS:Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) productionFormula:C28H30O10Purity:98%Color and Shape:SolidMolecular weight:526.53NT-0796
CAS:NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.Formula:C23H27N3O4Purity:99.67%Color and Shape:SolidMolecular weight:409.48DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6IMD-vanillin
CAS:IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purity:100% - 99.15%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Zharp1-211
CAS:Zharp1-211 is a RIPK3 inhibitor,reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.Formula:C24H25N5O4Purity:99.71%Color and Shape:SolidMolecular weight:447.494-Hydroxychalcone
CAS:4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.Formula:C15H12O2Purity:99.75%Color and Shape:Yellow PowderMolecular weight:224.25Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Formula:C34H44O19Purity:98% - 98.78%Color and Shape:SolidMolecular weight:756.7GSK-843
CAS:GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be used as an adjunctive treatment for inflammation.Formula:C19H15N5S2Purity:99.18%Color and Shape:SolidMolecular weight:377.49Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Formula:C40H36O12Purity:97.76% - 98.54%Color and Shape:SolidMolecular weight:708.71Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurity:98.35% - 99.95%Color and Shape:Needles From Benzene Or Alcohol SolidMolecular weight:234.344-O-Methyl honokiol
CAS:4-O-Methyl honokiol (4-O-Methylhonokiol), derived from Magnolia officinalis and Magnolia officinalis, is a PPARγ agonist with antiangiogenic properties.Formula:C19H20O2Purity:99.31%Color and Shape:SolidMolecular weight:280.36Ref: TM-T10153
1mg57.00€5mg120.00€10mg187.00€25mg354.00€50mg528.00€100mg758.00€500mg1,568.00€1mL*10mM (DMSO)131.00€IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63Ref: TM-T6176
1mg40.00€2mg52.00€5mg88.00€10mg139.00€25mg245.00€50mg406.00€100mg607.00€200mg845.00€1mL*10mM (DMSO)87.00€CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purity:99.62%Color and Shape:SolidMolecular weight:491.5Ref: TM-T9027
1mg35.00€2mg52.00€5mg77.00€10mg87.00€25mg170.00€50mg311.00€100mg535.00€1mL*10mM (DMSO)84.00€Lobeglitazone Sulfate
CAS:Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.Formula:C24H26N4O9S2Purity:98.69%Color and Shape:SolidMolecular weight:578.61Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oralFormula:C19H17ClN2O3Purity:98.16% - 98.84%Color and Shape:SolidMolecular weight:356.8RI-962
CAS:RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Formula:C28H28N6O2Purity:99.39%Color and Shape:SoildMolecular weight:480.56Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purity:98.92% - 99.64%Color and Shape:White Crystal PowderMolecular weight:608.72
