NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
Sort by
NP3-146
CAS:NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.Formula:C20H27ClN2O5SPurity:99.21%Color and Shape:SolidMolecular weight:442.96RIPK2-IN-5
CAS:RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the study of diseases caused by immune dysfunctions.Formula:C21H14N4SPurity:98.85%Color and Shape:SoildMolecular weight:354.43Sappanone A
CAS:Sappanone A is a high isoflavanone with anti-inflammatory properties.Sappanone A reduces allergic airway inflammation in ovalbumin-induced asthma.Formula:C16H12O5Purity:97.48% - 99.18%Color and Shape:SolidMolecular weight:284.26Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purity:100% - 99.61%Color and Shape:SolidMolecular weight:256.25NF-κB/MAPK-IN-1
CAS:NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).Formula:C27H27NO7Purity:97.03%Color and Shape:SolidMolecular weight:477.51Ref: TM-T63119
1mg47.00€2mg60.00€5mg87.00€10mg154.00€25mg329.00€50mg492.00€100mg710.00€1mL*10mM (DMSO)93.00€CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formula:C21H25ClN2O2Purity:98.59% - 99.35%Color and Shape:SolidMolecular weight:372.88Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Formula:C27H30O7Purity:95.84% - 99.4%Color and Shape:SolidMolecular weight:466.52Ref: TM-T16324
1mg88.00€5mg216.00€10mg376.00€25mg810.00€50mg1,074.00€100mg1,454.00€200mg1,882.00€1mL*10mM (DMSO)235.00€IRAK-1-4 Inhibitor I
CAS:IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.Formula:C20H21N5O4Purity:100% - 99.89%Color and Shape:SolidMolecular weight:395.41Ref: TM-T2457
1mg44.00€5mg79.00€10mg110.00€25mg224.00€50mg376.00€100mg540.00€500mg1,130.00€1mL*10mM (DMSO)79.00€Stipuleanoside R2
CAS:Stipuleanoside R2 is a triterpenoid saponin that inhibits NF-κB activation and has potential applications in inflammation, immunology, and cancer research.Formula:C53H84O23Purity:98%Color and Shape:SolidMolecular weight:1089.22Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1Sootepin D
CAS:Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.Formula:C31H48O4Purity:98%Color and Shape:SolidMolecular weight:484.71IMD-0560
CAS:IMD-0560 is a novel inhibitor of IκB kinase β.Formula:C15H8BrF6NO2Purity:99.51%Color and Shape:SolidMolecular weight:428.12Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formula:C20H17FO3SPurity:99.09% - 99.15%Color and Shape:Yellow SolidMolecular weight:356.41Goshonoside F5
CAS:Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.Formula:C32H54O13Purity:98%Color and Shape:SolidMolecular weight:646.771CID-2858522
CAS:CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Formula:C28H39N3O3Purity:96.11%Color and Shape:SolidMolecular weight:465.63Kuromanin chloride
CAS:Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators of gene regulation and signal transductionFormula:C21H21ClO11Purity:97.27% - 98.69%Color and Shape:SolidMolecular weight:484.84Ref: TM-T3406
1mg35.00€2mg50.00€5mg82.00€10mg110.00€25mg207.00€50mg306.00€100mg459.00€1mL*10mM (DMSO)88.00€IRAK4-IN-27
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 nM.Formula:C23H22N6O3Purity:98%Color and Shape:SolidMolecular weight:430.46Cantleyoside
CAS:Cantleyoside, a natural cyclic enol ether terpene glycoside from Pterocephalus hookeri, can activate of the AMPK/Sirt1/NF-κB signaling pathway.Formula:C33H46O19Purity:99.85%Color and Shape:SolidMolecular weight:746.71TNFα activity modulator 3
CAS:TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting TNFα-induced NF-κB activation, making it applicable for related research.Formula:C27H24F2N6O2Color and Shape:SolidMolecular weight:502.52BAL-0028
CAS:BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.Formula:C24H22FN3O2Purity:99.16%Color and Shape:SoildMolecular weight:403.45
