NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Products of "NF-κB"
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PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurity:99.89% - ≥98%Color and Shape:SolidMolecular weight:290.48Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35Suberosin
CAS:Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Formula:C15H16O3Purity:97.08% - 99.12%Color and Shape:SolidMolecular weight:244.298-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFormula:C23H24O5Purity:99.04% - 99.76%Color and Shape:SolidMolecular weight:380.43Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.7Anti-osteoporosis agent-4
Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.Formula:C26H26ClN3O7SPurity:98%Color and Shape:SolidMolecular weight:560.02QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:98.16% - 99.17%Color and Shape:White SolidMolecular weight:356.42Ref: TM-T6204
1mg43.00€2mg57.00€5mg93.00€10mg140.00€25mg226.00€50mg329.00€100mg490.00€1mL*10mM (DMSO)93.00€IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.Purity:99.15%Color and Shape:SolidMolecular weight:N/ARef: TM-TP1615L
1mg131.00€2mg173.00€5mg255.00€10mg374.00€25mg625.00€50mg890.00€100mg1,206.00€500mg2,422.00€IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Formula:C22H26ClN3O4Purity:98%Color and Shape:SolidMolecular weight:431.91Okanin
CAS:Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Formula:C15H12O6Purity:95.19% - 99.4%Color and Shape:SolidMolecular weight:288.25Ref: TM-TN2008
1mg88.00€5mg259.00€10mg311.00€25mg525.00€50mg750.00€100mg1,017.00€1mL*10mM (DMSO)217.00€RIP1 kinase inhibitor 7
CAS:RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM.Formula:C20H20FN3OPurity:98%Color and Shape:SolidMolecular weight:337.39Barlerin
CAS:Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFormula:C19H28O12Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:448.42Ref: TM-T5S1632
1mg40.00€2mg52.00€5mg85.00€10mg115.00€25mg245.00€50mg354.00€100mg533.00€1mL*10mM (DMSO)92.00€14-Deoxy-11,12-didehydroandrographolide
CAS:14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.Formula:C20H28O4Purity:98.55% - 99.93%Color and Shape:SolidMolecular weight:332.43Ref: TM-TQ0185
1mg69.00€5mg187.00€10mg274.00€25mg465.00€50mg677.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)145.00€SP-100030
CAS:SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Formula:C14H5ClF9N3OPurity:99.57%Color and Shape:SolidMolecular weight:437.65Ref: TM-T24816
1mg35.00€5mg73.00€10mg104.00€25mg243.00€50mg378.00€100mg542.00€500mgTo inquire1mL*10mM (DMSO)82.00€RIPK1-IN-25
RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.Color and Shape:Odour SolidGanoderic acid H
CAS:Ganoderic acid H inhibits AP-1/NF-κB, suppressing uPA to exert antitumor effects.Formula:C32H44O9Purity:95% - 97.14%Color and Shape:SolidMolecular weight:572.69Galloylpaeoniflorin
CAS:Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Formula:C30H32O15Purity:97.1%Color and Shape:SolidMolecular weight:632.57Necrostatin 2 racemate
CAS:Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.Formula:C13H12ClN3O2Purity:98% - 99.50%Color and Shape:SolidMolecular weight:277.71Ref: TM-T7504
1mg65.00€5mg107.00€10mg169.00€25mg305.00€50mg527.00€100mg743.00€500mg1,510.00€1mL*10mM (DMSO)140.00€Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:100% - 99.97%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg52.00€10mg64.00€25mg80.00€50mg96.00€100mg144.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)52.00€
