CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Products of "CCR"
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Nifeviroc
CAS:Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.Formula:C33H42N4O6Purity:98.14%Color and Shape:SolidMolecular weight:590.71CCR2 antagonist 4
CAS:CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nMFormula:C21H21ClF3N3O2Purity:99.63%Color and Shape:SolidMolecular weight:439.86Ref: TM-T13114
1mg52.00€5mg120.00€10mg188.00€25mg329.00€50mg490.00€100mg697.00€1mL*10mM (DMSO)133.00€AZ084
CAS:AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.Formula:C26H34N4O2Purity:97.12%Color and Shape:SolidMolecular weight:434.57Ref: TM-T10425
1mg88.00€5mg170.00€10mg259.00€25mg429.00€50mg605.00€100mg815.00€200mg1,093.00€1mL*10mM (DMSO)182.00€RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.49% - 98.64%Color and Shape:SolidMolecular weight:417.5CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Formula:C17H25FN2O2Purity:100%Color and Shape:SolidMolecular weight:308.39Ref: TM-T10712
1mg70.00€5mg156.00€10mg239.00€25mg419.00€50mg562.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)170.00€CMPD167
CAS:CMPD167 (MRK-1) is a potent, orally active inhibitor of CCR5 with significant in vitro antiviral efficacy [1].Formula:C35H47FN4O2Purity:98%Color and Shape:SolidMolecular weight:574.77Cenicriviroc Mesylate
CAS:Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory and antiinfective activity.Formula:C42H56N4O7S2Purity:98%Color and Shape:SolidMolecular weight:793.05PF-04634817
CAS:PF-0463481: safe, well-tolerated, dual CCR2/CCR5 antagonist for diabetic nephropathy; similar human/rodent CCR2 potency, less rodent CCR5 effect.Formula:C25H36F3N5O3Purity:98%Color and Shape:SolidMolecular weight:511.58AZD2423
CAS:AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM forFormula:C20H29ClFN5O2Purity:98%Color and Shape:SolidMolecular weight:425.93C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purity:100.00% - 99.74%Color and Shape:SolidMolecular weight:467.65Ref: TM-T21870
1mg51.00€2mg71.00€5mg96.00€10mg153.00€25mg303.00€50mg469.00€100mg655.00€1mL*10mM (DMSO)96.00€Azirkitug
Azirkitug is a humanized IgG1κ antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidRS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purity:97.64%Color and Shape:SolidMolecular weight:390.4CCR2-RA-[R]
CAS:CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).Formula:C18H19ClFNO3Purity:99.70%Color and Shape:SolidMolecular weight:351.8CCR6 antagonist 1
CAS:CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.Formula:C17H12F3NO2Purity:99.89%Color and Shape:SoildMolecular weight:319.28Ref: TM-T60145
1mg37.00€2mg52.00€5mg79.00€10mg111.00€25mg227.00€50mg329.00€100mg510.00€200mg722.00€1mL*10mM (DMSO)87.00€SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purity:99.11%Color and Shape:SolidMolecular weight:378.38BMS-817399
CAS:BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.Formula:C23H36ClN3O4Purity:99.05%Color and Shape:SolidMolecular weight:454Ref: TM-T26861
1mg160.00€5mg338.00€10mg512.00€25mg812.00€50mg1,093.00€100mg1,473.00€1mL*10mM (DMSO)376.00€CCR1 antagonist 9
CAS:CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).Formula:C20H16FN5O3SColor and Shape:SolidMolecular weight:425.44GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Color and Shape:SolidMolecular weight:451.35Cafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidDenrakibart
Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.Color and Shape:Odour LiquidINCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purity:99.55% - 99.82%Color and Shape:SolidMolecular weight:520.54
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