CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Products of "CCR"
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Lanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidINCB3344
CAS:INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8Formula:C29H34F3N3O6Purity:98.00% - 98.2%Color and Shape:SolidMolecular weight:577.59Ref: TM-TQ0103
1mg70.00€5mg153.00€10mg243.00€25mg411.00€50mg610.00€100mg868.00€1mL*10mM (DMSO)188.00€PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purity:98.85% - 99.47%Color and Shape:SolidMolecular weight:568.59BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Formula:C23H27N5O3SPurity:99.83%Color and Shape:SolidMolecular weight:453.56CCX140
CAS:CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.Formula:C20H13ClF3N5O3SPurity:97.58% - 99.95%Color and Shape:SolidMolecular weight:495.86Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Formula:C22H21ClN2O4SPurity:99.23%Color and Shape:SolidMolecular weight:444.93Ref: TM-T17225
1mg105.00€5mg259.00€10mg406.00€25mg680.00€50mg938.00€100mg1,301.00€500mg2,593.00€1mL*10mM (DMSO)363.00€CCR8 antagonist 1
CAS:CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.Formula:C26H29N3O5SPurity:97.33%Color and Shape:SolidMolecular weight:495.59Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.Formula:C32H42F3N5O6Purity:97.51% - 98.16%Color and Shape:SolidMolecular weight:649.7RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purity:99.60% - 99.87%Color and Shape:SolidMolecular weight:383.27MLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.Formula:C32H32ClF3N2O6Purity:98.62%Color and Shape:SolidMolecular weight:633.05SB-649701
CAS:SB-649701 is a potent antagonist of the human CCR8 receptor, exhibiting a pIC50 value of 7.7, and is utilized in asthma research [1].Formula:C27H28N4O3Purity:98%Color and Shape:SolidMolecular weight:456.54SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purity:99.59%Color and Shape:SolidMolecular weight:342.35AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurity:99.80% - 99.92%Color and Shape:SolidMolecular weight:334.18Ref: TM-T4300
1mg35.00€5mg70.00€10mg111.00€25mg230.00€50mg354.00€100mg530.00€500mg1,121.00€1mL*10mM (DMSO)78.00€CCR6 inhibitor 1
CAS:CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.Formula:C24H23F3N4O3SPurity:98.91%Color and Shape:SolidMolecular weight:504.52Ref: TM-T10715
1mg116.00€5mg283.00€10mg424.00€25mg682.00€50mg934.00€100mg1,301.00€500mg2,612.00€1mL*10mM (DMSO)311.00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13CCR2 antagonist 1
CAS:CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Formula:C28H32BrF3N2OColor and Shape:SolidMolecular weight:549.47BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Formula:C21H24ClFN4O3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:434.89Ref: TM-T2375
1mg38.00€5mg90.00€10mg124.00€25mg212.00€50mg329.00€100mg515.00€200mg782.00€1mL*10mM (DMSO)90.00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Formula:C35H56N10O15Purity:100%Color and Shape:SolidMolecular weight:856.88Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purity:98.35% - 98.71%Color and Shape:SolidMolecular weight:324.37Ref: TM-T6413
1mg57.00€5mg123.00€10mg187.00€25mg315.00€50mg472.00€100mg677.00€500mg1,388.00€1mL*10mM (DMSO)137.00€CCR3 antagonist 1
CAS:CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases.Formula:C19H21Cl2N3O4S2Purity:99.85%Color and Shape:SolidMolecular weight:490.42Ref: TM-T10156
1mg92.00€5mg188.00€10mg305.00€25mg489.00€50mg655.00€100mg883.00€1mL*10mM (DMSO)224.00€
