NOS
Nitric oxide synthase (NOS) is an enzyme responsible for the production of nitric oxide (NO), a signaling molecule involved in vasodilation, neurotransmission, and immune responses. There are three isoforms of NOS: neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), each playing distinct roles in physiological and pathological processes. Dysregulation of NOS activity is implicated in cardiovascular diseases, neurodegeneration, and inflammatory conditions. At CymitQuimica, we offer a selection of NOS modulators to support your research in vascular biology, neurobiology, and immunology.
Products of "NOS"
Sort by
26-Deoxyactein
CAS:23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affectingFormula:C37H56O10Purity:98.06%Color and Shape:SolidMolecular weight:660.832-Iminobiotin
CAS:2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).Formula:C10H17N3O2SPurity:98%Color and Shape:SolidMolecular weight:243.33Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Formula:C24H30O11Purity:100% - ≥95%Color and Shape:White To Off-White PowderMolecular weight:494.49anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purity:99.06% - 99.81%Color and Shape:SolidMolecular weight:903.06Stylopine hydrochloride
CAS:Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.Formula:C19H18ClNO4Purity:99.04%Color and Shape:SolidMolecular weight:359.8L-NIO dihydrochloride
CAS:L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formula:C7H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:209.67Neotuberostemonine
CAS:Neotuberostemonine, an antitussive from Stemona tuberosa, mitigates BLM-induced lung fibrosis by inhibiting macrophages.Formula:C22H33NO4Purity:99.91%Color and Shape:SolidMolecular weight:375.5Ref: TM-T4953
1mg51.00€5mg210.00€10mg311.00€25mg525.00€50mg750.00€100mg1,017.00€1mL*10mM (DMSO)172.00€Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32Ref: TM-T5688
1mg47.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)131.00€Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Formula:C22H28O11Purity:98.57% - 99.92%Color and Shape:SolidMolecular weight:468.45ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21Epibetulinic acid
CAS:Epibetulinic acid reduces inflammation, suppressing NO and prostaglandin E2 in endotoxin-stimulated mouse macrophages.Formula:C30H48O3Purity:99.02%Color and Shape:SolidMolecular weight:456.7Ref: TM-T2S0765
1mg52.00€5mg116.00€10mg170.00€25mg283.00€50mg419.00€100mgTo inquire1mL*10mM (DMSO)138.00€AVE-9488
CAS:AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.Formula:C16H14FNOPurity:99.87%Color and Shape:SolidMolecular weight:255.29TRIM
CAS:TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.Formula:C10H7F3N2Purity:98.98%Color and Shape:White SolidMolecular weight:212.17FK-330
CAS:FK-330 (FR-260330) is a novel nitric oxide synthase inhibitor that prevents ischemia and reperfusion injury in rat liver transplantation.Formula:C29H28ClF3N6O4Purity:99.89%Color and Shape:SolidMolecular weight:617.02Dimaprit dihydrochloride
CAS:Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.Formula:C6H15N3S·2HClPurity:99.79%Color and Shape:SolidMolecular weight:234.19Isoquercetin
CAS:1.Formula:C21H20O12Purity:98.08% - 99.29%Color and Shape:SolidMolecular weight:464.38Ref: TM-T5S0754
5mg49.00€10mg65.00€25mg97.00€50mg153.00€100mg221.00€200mg329.00€1mL*10mM (DMSO)50.00€Piceatannol 3'-O-glucoside
CAS:Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lungFormula:C20H22O9Purity:100% - 99.68%Color and Shape:SolidMolecular weight:406.38Ref: TM-T3S0401
1mg71.00€2mg92.00€5mg150.00€10mg217.00€25mg369.00€50mg540.00€100mg772.00€200mg1,074.00€Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.177-Nitroindazole
CAS:7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.Formula:C7H5N3O2Purity:96.15%Color and Shape:Orange-Yellow SolidMolecular weight:163.13iNOS-IN-14
CAS:iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.Formula:C8H4BrN3Purity:99.68%Color and Shape:SolidMolecular weight:222.04PRE-084 hydrochloride
CAS:PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).Formula:C19H28ClNO3Purity:99.54%Color and Shape:SolidMolecular weight:353.88Ref: TM-T3198L
5mg44.00€10mg65.00€25mg120.00€50mg207.00€100mg369.00€200mg565.00€1mL*10mM (DMSO)72.00€2,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFormula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12Physalin L
CAS:Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.Formula:C28H32O10Purity:98%Color and Shape:SolidMolecular weight:528.55Continentalic acid
CAS:Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S.Formula:C20H30O2Purity:98.39%Color and Shape:SolidMolecular weight:302.453-O-Acetyl-16α-hydroxydehydrotrametenolic acid
CAS:3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NOFormula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72Carboxyebselen
CAS:Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.Formula:C14H9NO3SePurity:98%Color and Shape:SolidMolecular weight:318.19L-Arginine hydrochloride
CAS:L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.Formula:C6H15ClN4O2Purity:99.51%Color and Shape:White Solid CrystallineMolecular weight:210.66NOS1-IN-1
CAS:NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.Formula:C14H24F9N7O8Purity:99.7%Color and Shape:SolidMolecular weight:589.37Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.7Tirucallol
CAS:Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of actionFormula:C30H50OPurity:99.98%Color and Shape:SolidMolecular weight:426.72Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:100% - 99.47%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg51.00€5mg88.00€10mg126.00€25mg216.00€50mg328.00€100mg487.00€500mg1,093.00€1mL*10mM (DMSO)96.00€Neoandrographolide
CAS:Neoandrographolide has hypolipidemic, cardio-protective, anti-inflammatory effects, and enhances chemo-sensitivity without major liver harm.Formula:C26H40O8Purity:98.52% - 99.00%Color and Shape:Less Columnar Crystal Colorless Columnar CrystalMolecular weight:480.59Ref: TM-T3884
1mg74.00€5mg164.00€10mg254.00€25mg430.00€50mg620.00€100mg870.00€500mg1,738.00€1mL*10mM (DMSO)173.00€Myricetin 3-O-galactoside
CAS:Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation andFormula:C21H20O13Purity:99.38%Color and Shape:SolidMolecular weight:480.38Isosorbide dinitrate
CAS:Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.Formula:C6H8N2O8Purity:99.72%Color and Shape:Hard Colorless Crystals SolidMolecular weight:236.14Ref: TM-T1479
10mg44.00€25mg84.00€50mg124.00€100mg187.00€200mg283.00€500mg487.00€1mL*10mM (DMSO)35.00€2-Iminobiotin hydrobromide
CAS:2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOSFormula:C10H18BrN3O2SPurity:98.13%Color and Shape:SolidMolecular weight:324.24Crocin II
CAS:Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.Formula:C38H54O19Purity:98% - 99.19%Color and Shape:SolidMolecular weight:814.82S-(2-aminoethyl) Isothiourea (dihydrobromide)
CAS:S-(2-aminoethyl) isothiourea inhibits all NOS types: Ki for nNOS 1.8μM, eNOS 2.1μM, iNOS 0.59μM.Formula:C3H11Br2N3SPurity:99.77%Color and Shape:SolidMolecular weight:281.02Agmatine sulfate
CAS:Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid.Formula:C5H16N4O4SPurity:99.56% - 99.86%Color and Shape:White To Off-White PowderMolecular weight:228.27Methylene Blue trihydrate
CAS:Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.Formula:C16H24ClN3O3SPurity:95.42% - 98.91%Color and Shape:Dark Green SolidMolecular weight:373.9Aminoguanidine hydrochloride
CAS:Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.Formula:CH6N4·HClPurity:99.80%Color and Shape:White To Off-White SolidMolecular weight:110.557-Ethoxyresorufin
CAS:7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.Formula:C14H11NO3Purity:99.09% - 99.35%Color and Shape:Red SolidMolecular weight:241.24Banoxantrone dihydrochloride
CAS:Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.Formula:C22H30Cl2N4O6Purity:98.84% - 98.93%Color and Shape:SolidMolecular weight:517.4Ref: TM-T10459
5mg79.00€10mg97.00€25mg165.00€50mg235.00€100mg346.00€500mg832.00€1mL*10mM (DMSO)96.00€3-Bromo-7-nitroindazole
CAS:3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.Formula:C7H4BrN3O2Purity:97.44%Color and Shape:Yellowish SolidMolecular weight:242.03
